A5005428468- Head and Neck Surgical Oncology
- Vascular Malformations Diagnosis and Treatment
- Meningioma and schwannoma management
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Lung Cancer Treatments and Mutations
- Urinary Tract Infections Management
- Cerebrospinal fluid and hydrocephalus
- Pituitary Gland Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Urinary Bladder and Prostate Research
- Hydrogen Storage and Materials
- Astronomy and Astrophysical Research
- Colorectal Cancer Treatments and Studies
- Nephrotoxicity and Medicinal Plants
- Photocathodes and Microchannel Plates
- Growth Hormone and Insulin-like Growth Factors
- Pericarditis and Cardiac Tamponade
- Vascular Malformations and Hemangiomas
- Acute Ischemic Stroke Management
- Hybrid Renewable Energy Systems
- Peptidase Inhibition and Analysis
- Renal cell carcinoma treatment
- Neurofibromatosis and Schwannoma Cases
- Venous Thromboembolism Diagnosis and Management
Institute of Brain and Blood Vessels
2021-2025
Keio University
1999-2024
Waseda University
2011-2024
Yokohama City University
2015-2024
Nippon Medical School
2024
Kochi Medical School Hospital
2024
St. Marianna University School of Medicine
2024
Tokyo Denki University
2017-2021
Keio University Hospital
2021
Shizuoka City Shimizu Hospital
2017-2020
Objective To clarify the role of Rho small GTP‐binding protein (Rho) in progression testicular germ cell tumour (GCT), by examining expression levels mRNAs genes GCT. Patients and methods The mRNA RhoA, RhoB RhoC were analysed surgical specimens GCT tissues from 45 consecutive Japanese patients, corresponding unaffected tissue originating same patient, using reverse transcription‐polymerase chain reaction. compared with those relationship between their tumours stage evaluated. also evaluated...
Abstract Since the venous system is affected by gravity, upright computed tomography (CT) in addition to conventional supine CT has great potential for evaluating postural changes system. We evaluated morphological differences head and neck vessels performing a contrast study both sitting positions. In this study, 20 included participants (10 men 10 women) were healthy adults aged 30 55 years. The cross-sectional area of cervical vessels, craniocervical junction veins, intracranial obtained...
<title>Abstract</title> <bold>Purpose </bold>The transradial approach is increasingly used in neurointervention due to its minimally invasive nature and lower risk of severe access-related complications. However, radial artery steno-occlusion, though generally asymptomatic, may restrict future vascular access. This study evaluates the incidence, predictors, recanalization puncture steno-occlusion following trans-wrist neurointervention. <bold>Methods </bold>A retrospective institutional...
Abstract Background PET/CT imaging with Zirconium-89 labeled [89Zr]Zr-DFO-girentuximab, which targets tumor antigen CAIX, may aid in the differentiation and characterization of clear cell renal carcinomas (RCC) other extrarenal lesions, has been studied European American cohorts. We report results from a phase I study that evaluated safety profile, biodistribution, dosimetry [89Zr]Zr-DFO-girentuximab Japanese patients suspected RCC. Methods Eligible adult received 37 MBq (± 10%; 10 mg mass...
The histopathology of the liver in idiopathic portal hypertension (IPH) associated with autoimmune disease (15 cases), was examined and compared that IPH without (31 cases). It found hepatic heterogeneous cases disease. That is, 7 similar to classic disease, remaining 8 disclosed unusual lesions such as focal non-suppurative cholangitis, nodular parenchymal hyperplasia, moderate inflammation, intrahepatic ductopenia. These lesions, which frequently coexisted same case, were not typical ones...
Background: Osimertinib is a standard treatment for patients with EGFR-mutant non-small cell lung cancer (NSCLC).Although some osimertinib resistance mechanisms have been identified, nearly 50% of the remain to be elucidated.This study was aimed at identifying non-genetic underlying resistance. Methods:We established two osimertinib-resistant lines from EGFR mutation-positive PC-9 and HCC827 NSCLC (PC-9OR HCC827OR, respectively) using stepwise method.We compared phosphoproteomic profiles...
<title>Abstract</title> Cerebrospinal fluid (CSF) leakage is a common complication associated with endoscopic endonasal skull-base surgery (EESBS). Postoperative mobilization-associated postural changes are considered to cause CSF leakage. However, no study has demonstrated robust relationship between and We used upright computed tomography (CT) clarify the effects of on reconstructed skull base (RSB) after EESBS. Thirty patients who underwent EESBS at our institution were prospectively...
We experimentally studied hydrogen desorption from MgH2 by supplying heat via a hot gas flow. Porous sheets of held in sponge-like carbon nanotube (CNT) matrix were developed and placed coaxial double-tube reactor. Ar was heated using cylindrical heater then flowed alongside the MgH2-CNT sheets, thereby increasing temperature enabling into The total energy efficiency approximately 6.2% when 64% desorbed. A numerical simulation conducted for transfer desorption, obtained results consistent...
We propose using hydrogen as a heat transfer medium to supply waste from hydrogen-driven devices storage tanks. In our model, MgH2 is used in the form of porous sheets, set parallel tank, and supplied via hot flowed through interspaces between sheets. Feasibility desorption reaction this process was verified numerically. Hydrogen efficiently carried stack sheets convective then into conductive pores owing its high thermal conductivity. found that also fast enough allow be drive endothermic...
Molecular genetic analyses of archival formalin-fixed, paraffin-embedded (FFPE) pathological specimens taken at biopsy or autopsy, are occasionally compromised because the DNA molecules therein inevitably degraded. Furthermore, since these tissue samples comprise various cell types, based on mixtures such heterogeneous populations often fail to reflect nature affected cells. In present study, elucidate contribution β-catenin gene mutation fundic gland polyp and heterotopic gastric mucosa in...
Arteriovenous fistulas at the craniocervical junction are rare vascular malformations with frequent hemorrhagic presentations, which may have a concurrent pial feeder aneurysm. A 65-year-old man presented subarachnoid hemorrhage and angiography showed an epidural arteriovenous fistula C-2 level anterior spinal aneurysm without perimedullary venous drainage. Transarterial coil embolization of ruptured partial Onyx shunt led to thrombosis However, three years later increased flow recurrence...
AIM:To present a case series describing an endoscopic technique with small craniotomy for recurrent chronic subdural hematoma (rCSDH) treatment. MATERIAL and METHODS:A total of 17 patients rCSDH underwent neuroendoscopic removal under local or general anesthesia.The skin incision the initial surgery on convexity skull was extended, burr hole created craniotomy.After outer membrane through craniotomy, evacuated suction tube using rigid endoscope.The entire cavity circumference irrigated,...
Pial arteriovenous fistula (AVF) is a vascular fistulous disease in which the cerebral pial artery and vein are directly connected without intervening nidus within sub-pial space. Multi-hole AVFs, wherein multiple feeders flow into one drainer, usually formed with complex angioarchitecture difficult to treat.A rare case of an adult patient hereditary hemorrhagic telangiectasia multi-hole AVF was described. A 23-year-old woman referred our hospital. She previously diagnosed left cerebellar...
The authors describe a 21-year-old man in whom large arteriovenous malformation of the scalp was eliminated using combined interventional, neuroradiological and neurosurgical approach. Embolization utilized to reduce arterial blood supply malformation. Eudragit-E, as liquid embolic material from cationic polymer, methyl butyl methacrylate, dimethylaminoethyl methacrylate copolymer, injected through transarterial route then by direct percutaneous puncture nidus. One week after embolization,...
Abstract Only few studies have assessed brain shift caused by positional change. This study aimed to identify factors correlated with a large postneurosurgical (PBS). Sixty-seven patients who underwent neurosurgical procedures had upright computed tomography (CT) scan using settings similar those of conventional supine CT. The presence clinically significant PBS, defined as ≥ 5 mm change, was evaluated. clinical and radiological findings were investigated associated larger PBS. As result,...