A5101543047- Diabetes Management and Research
- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
- Retinal Diseases and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Retinal Development and Disorders
- Pancreatic function and diabetes
- Retinal Imaging and Analysis
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Aldose Reductase and Taurine
- Diabetes Management and Education
- Vagus Nerve Stimulation Research
- Heart Rate Variability and Autonomic Control
- Erythropoietin and Anemia Treatment
- Diet and metabolism studies
- Glaucoma and retinal disorders
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Prenatal Substance Exposure Effects
- COVID-19 Clinical Research Studies
- Biochemical Acid Research Studies
Agostino Gemelli University Polyclinic
2011-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2022
IRCCS Ospedale San Raffaele
2019
Università Cattolica del Sacro Cuore
2002-2018
University of Padua
2017
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2014
Ospedale Sant Antonio
2014
Ospedale Antonio Cardarelli
2014
Ospedale Santa Maria
2014
Institut Català de Traumatologia i Medicina de l'Esport
2014
Inhibitors of HMG‐CoA reductase are new safe and effective cholesterol‐lowering agents. Elevation alanine‐amino transferase (ALT) aspartate‐amino (AST) has been described in a few cases myopathy with elevation creatinine kinase (CK) reported rarely. The inhibition affects also the biosynthesis ubiquinone (CoQ10). We studied two groups five healthy volunteers treated 20 mg/day pravastatin (Squibb, Italy) or simvastatin (MSD) for month. Then we 30 hypercholesterolemic patients double‐blind...
OBJECTIVE—Diabetes increases the risk of coronary heart disease (CHD) to a greater extent in women than men. We investigated whether type 1 diabetic patients with short duration and without complications have an altered oxidative status there are differences between men women. RESEARCH DESIGN AND METHODS—We 29 control subjects 37 uncomplicated diabetes 6 ± 3 years. RESULTS—Compared subjects, had lower total plasma antioxidant capacity (TRAP) (720.3 111.2 vs. 972.5 97.7 μmol/l men, P <...
Charcot neuroarthropathy is defined by painful or relatively painless bone and joint deformity in limbs that have lost sensory innervation (1). The incidence ∼0.1–5% diabetic patients with peripheral neuropathy (2,3). pathogenesis of unknown (1,4). In acute neuroarthropathy, osteoclast activity increases (5). Alendronate a bisphosphonate induces the apoptosis osteoclasts (6). utilization alendronate could improve clinical signs stop reabsorption. A total 20 consecutive new diagnosis were...
Diabet. Med. 27, 477–479 (2010) Abstract Aims The effect of a balanced, carbohydrate‐counting diet on glycaemic control in Type 1diabetic subjects is unclear. Our aim was to determine its small, pilot trial. Methods We randomized 256 1 diabetic Nutritional Education Programme (group A) or not B). Weight, body mass index, glycated haemogobin (HbA 1c ), lipid profile, urate, creatinine, microalbuminuria and daily insulin requirements were measured at baseline the end study (9 months). During...
Objective Psychophysical methods in patients with diabetes mellitus reveal deficits of central or foveal vision. Our aim was to evaluate the contrast-sensitivity thresholds 24 insulin-dependent (type I) diabetic a short disease duration and without retinopathy, taking into account metabolic control. Research Design Methods The control group consisted age-matched nondiabetic subjects. None had visual systemic symptoms. Contrast sensitivity measured at eight different spatial frequencies...
Charcot neuroarthropathy is a disabling complication of diabetes. Although its pathogenesis remains unknown, we suppose that genetics may play relevant role.We performed case-control study with 59 subjects diabetic (Ch group), 41 neuropathy without (ND and 103 healthy control (H group) to evaluate the impact two single nucleotide polymorphisms (SNPs) osteoprotegerin gene (G1181C T245G) on risk neuroarthropathy.Regarding SNPs G1181C, found significant linkage between G allele vs. ND, odds...
Abstract Aims Evaluate the safety and efficacy of once‐daily insulin detemir initiated in routine clinical practice patients with type 2 diabetes mellitus inadequately controlled oral hypoglycaemic agents ( OHAs ). Methods This large observational study was conducted 10 countries. Adverse event data (including hypoglycaemia) glycaemic control were recorded before 24 weeks following initiation while continued management. Results In this study, 17 374 (53% male) included. Mean pre‐insulin...
Background. La simulazione in ambito sanitario è una tecnica formativa che consente agli studenti e ai professionisti di sperimentare, un contesto protetto, situazioni cliniche tipiche del lavoro sanitario. Tale formazione può essere erogata attraverso diverse modalità, implicano la pratica riflessiva deliberata delle abilità acquisite forma teorica. Ad oggi, per quanto nostra conoscenza, numero limitato studi ha esplorato le differenze tra online presenza. Per questo, il presente contributo...
The electroretinogram (ERG) elicited by alternating gratings at constant mean luminance (pattern ERG) is a focal response reflecting the activity of directly stimulated retinal area. In addition, pattern ERG related, unlike flash ERG, to ganglion cell activity. Therefore, this technique may be used evaluate integrity inner layers in macular region. study, steady-state (1.7 cycles/deg spatial frequency; 9 degrees field size) temporally modulated 8 Hz, was recorded 42 type I...
The effects of diabetes on the neural retina before onset clinically detectable retinopathy can be investigated with electrophysiological methods. Our aim was to detect early retinal dysfunctions in 60 patients insulin-dependent mellitus (IDDM) and a short duration disease. We used steady-state focal (9° field size) electroretinogram (ERG) macula response luminance modulation uniform (flicker ERG) or counterphase-modulated sinusoidal gratings (pattern ERG). harmonic analysis flicker ERG...
In 1591 Italian subjects affected by SARS-COV-2, there was a prevalence of 17% type 2 diabetes [1Grasselli Giacomo Zangrillo Alberto Zanella Antonelli Massimo Cabrini Luca Castelli Antonio Cereda Danilo Coluccello Foti Giuseppe Fumagalli Roberto Iotti Giorgio Latronico Nicola Lorini Merler Stefano Natalini Piatti Alessandra Ranieri Marco Vito Scandroglio Anna Mara Storti Enrico Cecconi Maurizio Pesenti Baseline characteristics and outcomes patients infected With SARS-CoV-2 admitted to ICUs...