A5056118467- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Adolescent and Pediatric Healthcare
- Child and Adolescent Psychosocial and Emotional Development
- Electroconvulsive Therapy Studies
- Neurological disorders and treatments
- Obsessive-Compulsive Spectrum Disorders
- Advanced Neuroimaging Techniques and Applications
- Psychosomatic Disorders and Their Treatments
- Attention Deficit Hyperactivity Disorder
- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Epilepsy research and treatment
- Genetics and Neurodevelopmental Disorders
- Traumatic Brain Injury Research
- Eating Disorders and Behaviors
- Pain Management and Treatment
- Treatment of Major Depression
- Mental Health Treatment and Access
- Transcranial Magnetic Stimulation Studies
- Electrolyte and hormonal disorders
- Youth Substance Use and School Attendance
- Radiomics and Machine Learning in Medical Imaging
- Neural and Behavioral Psychology Studies
University of Cincinnati Medical Center
2014-2024
University of Cincinnati
2009-2024
West China Hospital of Sichuan University
2023
Chongqing Medical University
2023
First Affiliated Hospital of Zhengzhou University
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Sichuan University
2023
RWTH Aachen University
2022
Phoenix (United States)
2017
Texas Tech University
2015
Objective: Although adolescent-onset bipolar disorder is associated with significant morbidity, there have been few prospective outcome studies of this population. The aim study was to examine the 12-month adolescents following an initial hospitalization for a manic or mixed episode. Method: Bipolar (N=71) were recruited during their first episode and evaluated using diagnostic, symptomatic, functional assessments. Patients also at 1, 4, 8, 12 months after assess syndromic, outcomes....
Polyphenol compounds found in berry fruits, particular flavonoids, have been associated with health benefits including improvement cognition and neuronal function aging. Concord grape juice contains polyphenols, anthocyanins flavanols, previous research has shown a number of human conditions supplementation. In the current study, older adult subjects mild cognitive impairment consumed or placebo for 16 weeks were administered assessments memory brain activation pre- postintervention....
Strakowski SM, Fleck DE, DelBello MP, Adler CM, Shear PK, Kotwal R, Arndt S. Impulsivity across the course of bipolar disorder. Bipolar Disord 2010: 12: 285–297. © 2010 The Authors. Journal compilation John Wiley & Sons A/S. Objective: To determine whether abnormalities impulse control persist disorder, thereby representing potential state markers and endophenotypes. Methods: Impulse 108 I manic or mixed patients was measured on three tasks designed to study response inhibition, ability...
<h3>Context</h3> Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied. <h3>Objective</h3> To identify how sequence onsets a disorder and is associated with subsequent course each condition. <h3>Design</h3> Inception cohort. <h3>Setting</h3> Academic medical center. <h3>Patients</h3> Patients (N = 144) were studied who met criteria for I (manic or mixed), 12 to 45 years old, had no previous hospitalizations...
Bipolar I disorder is characterized by affective symptoms varying between depression and mania. The specific neurophysiology responsible for in bipolar unknown but previous neuroimaging studies suggest impairments corticolimbic regions that are regulating emotion. amygdala seems to play a central role this network appraisal of emotional stimuli. To further understand the generation mood symptoms, we used functional magnetic resonance imaging (fMRI) examine group patients with longitudinally.
Rates of clinical diagnoses schizophrenia in African American individuals appear to be elevated compared with other ethnic groups the United States, contradicting population rates derived from epidemiologic surveys.To determine whether would continue exhibit significantly higher schizophrenia, even after controlling for age, sex, income, site, and education, as well presence or absence serious affective disorder, determined by experts blinded race ethnicity. A secondary objective was if a...
<h3>Context</h3> Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome. <h3>Objective</h3> The primary goal of study was to identify how the relative onsets alcohol-use affect subsequent courses illness in patients both conditions. <h3>Design Setting</h3> Inception cohort at an academic medical center. <h3>Patients</h3> Patients meeting criteria for type I disorder, manic or mixed, ages 12 45 years,...
Objectives: Although previous research has shown that attentional dysfunction is common during acute mood episodes in individuals with bipolar disorder (BPD), few studies have examined whether deficits are evident periods of symptom stability. The goal this study was to determine clinically stable BPD would disturbances relative healthy subjects. Methods: Fourteen patients and 12 comparison subjects participated the study, were administered Degraded Stimulus Continuous Performance Test...
Clinically, African American psychiatric patients are disproportionately diagnosed with schizophrenia compared white patients. Why this occurs is unknown. Extending prior work, the authors hypothesized that first-rank symptoms distract clinicians so they fail to identify affective disorders in Americans.195 and at least 1 psychotic symptom (delusions, hallucinations, or prominent thought disorder) admission were recruited from January 1, 1998, through May 31, 2001. Each patient received 3...
Several lines of evidence suggest that bipolar disorder is associated with progressive changes in gray matter volume (GMV), particularly brain structures involved emotional regulation and expression. The majority these studies however, have been cross-sectional nature. In this study we compared baseline follow-up scans groups healthy subjects. We hypothesized subjects would demonstrate significant GMV over time.A total 58 48 participated structural magnetic resonance imaging (MRI). Subjects...
Objective: To determine whether specific aspects of impulsivity (response disinhibition, inability to delay gratification, inattention) differ between healthy and bipolar manic subjects, these were associated with each other severity affective symptoms. Methods: Performance 70 I or mixed patients was compared that 34 subjects on three tasks specifically designed study response inhibition, ability attention; namely, a stop signal task, delayed reward continuous performance respectively....
Despite different treatments and courses of illness, depressive symptoms appear similar in major disorder (MDD) bipolar I (BP-I). This similarity suggests significant overlap brain pathways underlying neurovegetative, mood, cognitive depression. These shared regions might be expected to exhibit activation individuals with MDD BP-I during functional magnetic resonance imaging (fMRI).fMRI was used compare regional participants (n = 25) a episode as well 25 healthy comparison (HC) participants....
Individualized treatment for bipolar disorder based on neuroimaging targets remains elusive. To address this shortcoming, we developed a linguistic machine learning system cascading genetic fuzzy tree (GFT) design called the LITHium Intelligent Agent (LITHIA). Using multiple objectively defined functional magnetic resonance imaging (fMRI) and proton spectroscopy (1 H-MRS) inputs, tested whether LITHIA could accurately predict lithium response in participants with first-episode mania.We...
The aim of this retrospective chart review was to evaluate the effectiveness and tolerability aripiprazole for treatment children adolescents with bipolar disorders.The medical charts all a DSM-IV diagnosis disorder, type I, II, not otherwise specified (NOS), or schizoaffective type, who were treated reviewed by two child adolescent psychiatrists independently confirmed their diagnoses, severity, improvement illness using Clinical Global Impression (CGI) Severity Improvement scores disorder...
Article AbstractBackground: African American patients may be less likely than white to adhere maintenance pharmacotherapy for bipolar disorder. The purpose of this study was examine rates medication nonadherence, self-perceived reasons and attitudes associated with nonadherence in these ethnic groups. Method: 20 30 subjects DSM-IV I disorder participated study. At a single follow-up visit at least 4 months after their first hospitalization acute mania, we assessed demographics, symptom...