About
Contact & Profiles
A5033736221
Research Areas
- Hedgehog Signaling Pathway Studies
- Virus-based gene therapy research
- Liver physiology and pathology
- Epigenetics and DNA Methylation
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
East China Normal University
2020
Shanghai Medical College of Fudan University
2017
10.1038/labinvest.2017.34
article
EN
publisher-specific-oa
Laboratory Investigation
2017-04-17
High interleukin 17A (IL-17A) expression in hepatocellular carcinoma (HCC) tissue promotes HCC development. This study explores a method to inhibit growth by neutralizing IL-17A the microenvironment. A novel type 5 adenoviral vector (Ad5) that carries DNA sequences encoding specific recombinant antibody fragments was developed this research. After locally injecting into tumor tissues, Ad5 transduced cells. leads of anti-IL-17A and consequently an inhibition IL-17A. The stability optimized...
10.1089/hum.2019.169
article
EN
Human Gene Therapy
2020-05-11
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