- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Transplantation: Methods and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Foot and Ankle Surgery
- Cardiac Valve Diseases and Treatments
- Tendon Structure and Treatment
- Renal Transplantation Outcomes and Treatments
- Cardiac Fibrosis and Remodeling
- Organ Transplantation Techniques and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Mechanical Circulatory Support Devices
- Winter Sports Injuries and Performance
- Intensive Care Unit Cognitive Disorders
- Heart Failure Treatment and Management
- Anesthesia and Neurotoxicity Research
- Congenital heart defects research
- Pain Management and Treatment
- Sports injuries and prevention
Medical University of Vienna
2012-2023
Vienna General Hospital
1999-2021
Hospital Clínico Universitario de Caracas
2012-2020
University of Vienna
1999-2006
Arbeitsgemeinschaft für Klinische Ernährung
2005
Milpark Hospital
2005
Columbia University
2001
Abstract Background Transcatheter tricuspid valve intervention became an option for pacemaker lead-associated regurgitation. This study investigated the progression of regurgitation (TR) in patients with or without pre-existing right ventricular dilatation (RVD) undergoing implantation. Methods Patients were included if they had implantation transtricuspid lead and completed echocardiography before after The cohort was divided RVD (cut-off basal RV diameter ≥ 42 mm). TR graded none/mild,...
Purpose: Reduced lead diameter and reliability can be designed into transvenous permanent pacing leads through use of redundant insulation removal the stylet lumen. The model 3830 (Medtronic Inc., Minneapolis, MN, USA) is a bipolar, fixed‐screw, steroid‐eluting, lumenless, 4.1‐Fr lead. Implantation performed in variety right heart sites using deflectable catheter (Model 10600, Medtronic). Lead performance safety were studied. Methods: Two prospective trials 338 implanted subjects from 56...
To evaluate the influence of two different ablation devices (microwave AFx and radiofrequency Medtronic), designed to create linear lesion lines, with respect efficacy restoration sinus rhythm (SR).Between February 2001 December 2002, 42 patients chronic, persistent atrial fibrillation (AF) >6 months were submitted combinations valve surgery (mitral+/-tricuspid, n = 30; mitral aortic+/-tricuspid reconstruction, 6 aortic+/-tricuspid, 8) concomitant Maze procedure. The biatrial followed...
Device implantation in chronic heart failure (CHF) for cardiac resynchronization therapy (CRT) with or without implantable cardioverter/defibrillator (ICD) is an established treatment option symptomatic patients under medical baseline therapy. Although recommended, the need optimization of was never proven. As 'the real world', not always up-titrated to desirable dosages; this provides opportunity evaluate impact optimizing who had received a device proven effectiveness.This observational...
Cardiac resynchronization therapy (CRT) is an established treatment option for symptomatic chronic heart failure (CHF) patients with pharmacological baseline therapy, but not all benefit from device therapy. One reason this may be inadequate settings. In real-world practice, echocardiographic evaluation of atrioventricular (AV) delay performed in a high proportion patients, as the effect electrical optimization CRT issue open investigation.We retrospective observational study analysing...
We report a rare but severe pacemaker complication of lead perforating the papillary muscle. This induced tricuspid regurgitation and right heart failure. Patients suffering from failure have an increased operative risk open-heart surgery therefore represent clinical challenge due to lack clear guidelines.A 70-year-old male patient presented with history decompensated One was described as 'whipping'. Four years earlier he had received VVIR passive lead. failed after three new ventricular...
To determine the degree of neurocognitive dysfunction after placement internal cardioverter defibrillators (ICD) and its relationship to extent neuronal injury, we studied 42 patients undergoing ICD (n = 21) or pacemaker (PM) insertion (control patients, n 21). The Mini Mental State Examination, Trailmaking A test forward backward Digit Span tests were used P300 latencies determined preoperatively postoperatively. Serum neuron-specific enolase (NSE) was before at end of, as well 2, 6, 24 h...
Abstract Aims Cardiac repair has steered clinical attention and remains an unmet need, because available regenerative therapies lack robust mechanistic evidence. Pressure‐controlled intermittent coronary sinus occlusion (PICSO), known to induce angiogenetic vasoactive molecules as well reduce regional ischemia, may activate endogenous processes in failing myocardium. We aimed investigate the effects of PICSO patients with advanced heart failure undergoing cardiac resynchronization therapy....
To study the cause of myocardial injury after elective transvenous insertion a cardioverter/defibrillator, we measured troponin T (TnT) release in 27 patients. Five patients needing only replacement generator with threshold testing served as controls. Compared to control group, significant increase TnT occurred undergoing insertion, which was greatest group receiving screw-in electrodes. There no correlation between and number energy shocks time fibrillation. Duration surgery were positively...
Introduction Evidence of sex-related differences in patients with pacemakers regarding comorbidities is insufficiently investigated. The aim this study was to determine the relationship cardiovascular and sex category properties pacemaker implantation, follow-up, long-term survival. Methods This retrospective, single-center cohort consisted 6362 pacemaker-patients (39.7% female) enrolled between May 2000 April 2015. Functional parameters were registered at regular controls. Survival status...
Abstract Background Electromagnetic interference between left ventricular assist devices (LVAD) and the telemetry wand of implantable cardioverter‐defibrillators (ICD) with impairment ICD interrogation has previously been described in HVAD HeartMate II devices. This is first study showing potential influence LVAD model 3 (with unique feature fully magnetically levitated rotor consistent wide blood‐flow gaps) on functional different models. Methods Results Among 51 patients treated a LVAD, 34...
The purpose of this prospective, randomized, open-label, phase II, multicenter study was to optimize the initial oral dose tacrolimus.A total 113 patients were randomly assigned low-dose (0.075 mg/kg/day, n=55) or high-dose (0.15 n=58) tacrolimus and followed for 3 months. Target whole-blood trough levels 10 20 ng/mL. Prophylactic use corticosteroids azathioprine identical in both groups, antibody induction mandatory. primary endpoint time incidence adjustment because toxicity rejection,...
Background: The aim of the study was to evaluate subcutaneous implantable cardioverter-defibrillator (S-ICD) patients with regard underlying etiology, peri-procedural outcome, appropriate/inappropriate shocks, and complications during follow-up. Methods: All who underwent S-ICD implantation from February 2013 March 2017 at an academic hospital in Vienna were included. Medical records examined follow-up interrogations devices conducted. Results: A total 79 (58.2% males) a mean age 44.5 ± 17.2...
SIMULTANEOUS cardiac transplantation and surgical repair of an aortic aneurysm (AA) has not been reported previously. Aortic aneurysms are rare in patients with end-stage heart failure who candidates for (HTX). To date, dilatation the thoracic aorta have only referred whose underlying disease was Mafar’s syndrome. However, presence AA regarded as contraindication this population. This article reviews first two cases whom cardiomyopathy developed were accepted eventually underwent successful...
To evaluate the incidence of reoperation due to complications or battery depletion in patients who underwent endocardial permanent pacemaker implantation during an 8-year period.All and related procedures from January 1996 June 2003 were retrospectively collected entered into a database. During this time period total number 3856 operations with 2242 primary implantations 1614 redo performed at our department. As 809 referred another hospital, where operation was done, these excluded further...
Background: We have previously reported that Pressure controlled Intermittent Sinus Coronary Occlusion (PICSO) – a coronary sinus intervention, applied primarily to reduce myocardial injury by redistributing flow into underperfused zones and inducing washout clearing the ischemic/reperfused microcirculation, is able enhance proliferation of human fibroblasts in culture. To test whether PICSO also clinically feasible treat patients with advanced heart failure we studied potential...