A5066114829- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
- Urinary Bladder and Prostate Research
- Esophageal Cancer Research and Treatment
- Pelvic floor disorders treatments
- Patient-Provider Communication in Healthcare
- Urinary Tract Infections Management
- Bacterial Identification and Susceptibility Testing
- Urological Disorders and Treatments
- Metabolomics and Mass Spectrometry Studies
- Advanced Chemical Sensor Technologies
- Identification and Quantification in Food
- Kidney Stones and Urolithiasis Treatments
- Hormonal and reproductive studies
- Genital Health and Disease
- Intraperitoneal and Appendiceal Malignancies
- Global Cancer Incidence and Screening
- Cerebrospinal fluid and hydrocephalus
- Ureteral procedures and complications
- Olfactory and Sensory Function Studies
- Pediatric Urology and Nephrology Studies
- Organ Donation and Transplantation
- Therapeutic Uses of Natural Elements
- Palliative Care and End-of-Life Issues
Aintree University Hospitals NHS Foundation Trust
2021-2024
University of Liverpool
2021-2024
Royal Liverpool University Hospital
2022-2023
Royal Liverpool and Broadgreen University Hospital NHS Trust
2019-2022
Broadgreen Hospital
2022
Calderdale and Huddersfield NHS Foundation Trust
2007
Abstract Objective To test and compare the efficacy of methenamine hippurate for prevention recurrent urinary tract infections with current standard prophylaxis daily low dose antibiotics. Design Multicentre, open label, randomised, non-inferiority trial. Setting Eight centres in UK, recruiting from June 2016 to 2018. Participants Women aged ≥18 years infections, requiring prophylactic treatment. Interventions Random assignment (1:1, using permuted blocks variable length via a web based...
Adjuvant intravesical chemotherapy following tumour resection is recommended for intermediate-risk non-muscle-invasive bladder cancer (NMIBC).To assess the efficacy and safety of adjuvant chemohyperthermia (CHT) NMIBC.HIVEC-II an open-label, phase 2 randomised controlled trial CHT versus alone in patients with NMIBC recruited at 15 centres between May 2014 December 2017 (ISRCTN 23639415). Randomisation was stratified by treating hospital.Patients were randomly assigned (1:1) to mitomycin C...
BACKGROUND: Recurrence of non–muscle-invasive bladder cancer (NMIBC) is common after transurethral resection tumor (TURBT). Photodynamic diagnosis (PDD) provides better diagnostic accuracy and more complete may reduce recurrence. However, there limited evidence on the longer-term clinical effectiveness cost-effectiveness PDD-guided resection. METHODS: In this pragmatic, open-label, parallel-group randomized trial conducted in 22 U.K. National Health Service hospitals, we recruited...
Abstract Background The diagnosis and surveillance of urothelial bladder cancer (UBC) require cystoscopy. There is a need for biomarkers to reduce the frequency cystoscopy in surveillance; urinary volatile organic compound (VOC) analysis could fulfil this role. This cross-sectional study compared VOC profiles patients with without UBC, investigate metabolomic signatures as biomarkers. Methods Urine samples were collected from haematuria clinic undergoing diagnostic UBC surveillance. Urinary...
Daily, low-dose antibiotic prophylaxis is the current standard care for women with recurrent urinary tract infection. Emerging antimicrobial resistance a global health concern, prompting research interest in non-antibiotic agents such as methenamine hippurate, but comparative data on their efficacy and safety are lacking.
Introduction Bladder cancer is the most frequently occurring tumour of urinary system. Ta, T1 tumours and carcinoma in situ (CIS) are grouped as non-muscle invasive bladder (NMIBC), which can be effectively treated by transurethral resection (TURBT). There limitations to visualisation with conventional TURBT using white light illumination within bladder. Incomplete resections occur from failure identify satellite lesions or full extent leading recurrence potential risk disease progression....
Background Around 7500 people are diagnosed with non-muscle-invasive bladder cancer in the UK annually. Recurrence following transurethral resection of tumour is common, and intensive monitoring schedule required after initial treatment has associated costs for patients NHS. In photodynamic diagnosis, before tumour, a photosensitiser that preferentially absorbed by cells instilled intravesically. Transurethral then conducted under blue light, causing to fluoresce. Photodynamic...
Objective In view of changing landscape surgical treatment for LUTS secondary to BPE, this audit was undertaken assess key aspects the processes and outcomes current interventional treatments across different units in UK. Materials method A multi-institutional snapshot conducted patients undergoing interventions LUTS/BPE over 8-week period. Using Delphi process two-part proforma designed capture data. Results 529 were included 20 NHS trusts England Wales. Median age 73 years. Indications...
Objectives: To compare patient-reported outcome measures (PROMs) for patients with symptomatic renal stone disease treated by flexible ureterorenoscopy (fURS) and shockwave lithotripsy (SWL) Introduction: Historically, surgical outcomes are measured surgeon-specific such as ‘stone-free rates’. More recently, there is increasing emphasis on PROMs to ascertain a patient’s perspective of their own outcome. Despite this, the literature in reference stone-specific following treatment remains...
You have accessJournal of UrologyCME1 Apr 2023PD13-02 CAN EXPERIENCE OF BLUE LIGHT CYSTOSCOPY IMPROVE A SURGEON'S WHITE RESECTION? DATA FROM THE PHOTO TRIAL Paul Gravestock, Thenmalar Vadiveloo, Rebecca Lewis, Anne Duncan, Steven Penegar, Emma Clark, Ge Yu, Paramananthan Mariappan, Joanne Cresswell, John Mcgrath, James N’dow, Ghulam Nabi, Hugh Mostafid, Kelly, Craig Ramsay, Henry Lazarowicz, Angela Allan, Matthew Breckons, Karen Campbell, Louise Andy Feber, Alison Mcdonald, Norrie, Giovany...
Introduction and Objectives: Bulking agents have been used for decades as an alternative treatment patients with stress urinary incontinence who are not appropriate surgery. Despite this their long-term complications poorly documented can be misdiagnosed. This paper presents a literature review the results of national survey members Section Female, Neurological Urodynamic Urology (FNUU) British Association Urological Surgeons (BAUS) identifying common widely bulking in clinical practice....
ABSTRACT Introduction Predict Prostate is a freely-available online personalised risk communication tool for men newly diagnosed with non-metastatic prostate cancer. Its accuracy has been assessed in multiple validation studies but the clinical impact of on patient decision-making had not previously evaluated. Methods A multi-centre randomised controlled trial was performed across 8 UK centres, wherein considering either active surveillance or radical treatment, were to standard care (SOC)...