K. Ashokkumar

ORCID: 0000-0003-0799-1540
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About
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Research Areas
  • Supercapacitor Materials and Fabrication
  • Gas Sensing Nanomaterials and Sensors
  • Synthesis and Biological Evaluation
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Advancements in Battery Materials
  • Copper-based nanomaterials and applications
  • Antibiotic Resistance in Bacteria
  • Electrochemical sensors and biosensors
  • Transition Metal Oxide Nanomaterials
  • Analytical Chemistry and Sensors
  • Bioactive Compounds and Antitumor Agents
  • Synthesis and biological activity
  • Crystallization and Solubility Studies
  • Catalytic C–H Functionalization Methods
  • Crystal structures of chemical compounds
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Nanomaterials for catalytic reactions
  • Advanced Photocatalysis Techniques
  • Electrochemical Analysis and Applications
  • Synthesis and Catalytic Reactions
  • Synthesis of Indole Derivatives
  • ZnO doping and properties
  • X-ray Diffraction in Crystallography
  • Drug Transport and Resistance Mechanisms
  • Synthesis and Reactions of Organic Compounds

Vellore Institute of Technology University
2021-2025

Annamalai University
2021-2024

R.V. College of Engineering
2023

University of Madras
2011

Seven-membered nitrogen heterocycles have a strong influence in drug discovery due to their inherent 3D character, which allows the ability explore vast conformational space with biological target. Notably, privileged 1,4-benzodiazepine scaffold is dominant treating central nervous system its binding affinity GABAA receptor. Herein, we report protocol for transformation of azidoquinones p-quinone fused 5-substituted-1,4-benzodiazepines (p-QBZDs) from InCl3-catalyzed intermolecular tandem...

10.1021/acs.joc.3c01810 article EN The Journal of Organic Chemistry 2023-11-15

Abstract Copper oxide nanoparticles (CuO-NPs) were synthesized by a hydrothermal method with different morphologies including nanorod, spherical, rock like and plate. Their structural properties, functional groups, surface morphology, pore size distribution electrochemical properties studied techniques X-ray diffraction, vibrational spectroscopy, Scanning Electron Microscopy cyclic voltammetry. XRD analysis confirmed the formation of orthorhombic structure reduced crystallite 13.23 nm. The...

10.21203/rs.3.rs-3979204/v1 preprint EN cc-by Research Square (Research Square) 2024-02-29

Abstract As an alternate for the conventional glass-based pH sensor which is associated with problems like fragile nature, alkaline error, and potential drift, development of a new redox-sensitive probe-modified electrode that could show potential, current-drift surface-fouling free voltammetric sensing demanding research interest, recently. Herein, we report substituted carbazole-quinone (Car-HQ) based redox-active pH-sensitive probe contains benzyl bromo-substituents, immobilized...

10.1038/s41598-021-93368-5 article EN cc-by Scientific Reports 2021-07-06

Nickel-doped manganese dioxide nanoparticles (Ni = 0.025, 0.05, 0.075, 0.1 and 0.125 M) were prepared via a facile hydrothermal method. Their structural properties, surface morphology, functional groups magnetic properties studied by different techniques like X-ray diffraction, Scanning Electron Microscopy vibrational spectroscopy. The XRD results revealed that the position of diffraction peaks agreed well with reflection tetragonal structure. crystallite size ranged from 9.2 to 27.61 nm....

10.1080/10667857.2022.2083483 article EN Materials Technology 2022-06-05

We designed a robust protocol to access p -quinone fused 5-substituted-1,4-benzodiazepine scaffolds, new molecular hybrid, through InCl 3 mediated Pictet–Spengler type cycloannulation of 2-amino-3-arylamino- and aldehydes.

10.1039/d4nj00993b article EN New Journal of Chemistry 2024-01-01

Antimicrobial resistance (AMR) is fast becoming a medical crisis affecting the entire global population. World Health Organization (WHO) statistics show that globally 0.7 million people are dying yearly due to emergence of AMR. By 2050, expected number lives lost will be 10 per year. Acinetobacter baumannii dreadful nosocomial pathogen has developed multidrug (MDR) several currently prescribed antibiotics worldwide. Overexpression drug efflux transporters (DETs) one mechanisms in baumannii....

10.1080/07391102.2023.2279287 article EN Journal of Biomolecular Structure and Dynamics 2023-11-08

In the title compound, C(20)H(22)O(5)S, dihedral angle between mean planes through thio-phene and benzene rings is 75.2 (1)°. The meth-oxy group essentially coplanar with ring, largest deviation from plane being 0.019 (2) Å for O atom. malonate assumes an extended conformation.

10.1107/s1600536811022525 article EN cc-by Acta Crystallographica Section E Structure Reports Online 2011-06-18
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