A5021351666- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Mycobacterium research and diagnosis
- Diphtheria, Corynebacterium, and Tetanus
- Bacteriophages and microbial interactions
- Bone Tissue Engineering Materials
- Streptococcal Infections and Treatments
- Plant Pathogenic Bacteria Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Gut microbiota and health
- Microbial Metabolism and Applications
- Radioactive element chemistry and processing
- Malaria Research and Control
- Ocular Infections and Treatments
- Evolution and Genetic Dynamics
- Bacterial Infections and Vaccines
- Pharmacological Effects of Natural Compounds
- Microbial infections and disease research
- Infective Endocarditis Diagnosis and Management
Pondicherry University
2015-2025
Sri Balaji Vidyapeeth University
2024
MNR Dental College and Hospital
2024
University of Malaya
2024
Straumann (Switzerland)
2017
Pondicherry Institute of Medical Sciences
2008-2010
L V Prasad Eye Institute
2010
Centre for DNA Fingerprinting and Diagnostics
2004-2006
Jawaharlal Institute of Post Graduate Medical Education and Research
2000-2006
Although not previously known to cause human infections, Kocuria species have now emerged as pathogens, mostly in compromised hosts with severe underlying disease. Recently, there has been an increasing incidence of different types infections reported, most likely due the adoption better identification methods. Here, we report a case peritonitis caused by rosea diabetic nephropathy patient who was on continuous ambulatory peritoneal dialysis. Sepsis and K. our yielded two identical isolates...
Nosocomial infections caused by Acinetobacter baumannii often prove difficult to treat owing their multiple drug resistance. Carbapenems play a pivotal role in the management of severe infections. However, reports carbapenem resistance have been increasing alarmingly due production variety carbapenemases including metallo-beta-lactamases (MBLs). This study investigated both phenotypic and genotypic assays prevalence MBLs total 55 A. strains isolated from South Indian tertiary care hospital....
Bombyx mori, an insect, is of great economic value, widely known for the production silk. Nosema bombycis, intracellular parasite, often infects it and causes a fatal disease - Pebrine which affects development worm. The infected larvae silkworms are coated with brown spot. It also loss appetite, makes them sluggish opaque, ultimately resulting in death. proteins studied here SWP12 SWP30, both exosporal protein found N.bombycis. chitin-binding protein, involved spore walls. acts as important...
Purpose: To study the qualitative and quantitative methods for investigation of biofilm formation to examine correlation between antibiotic resistance among clinical isolates Acinetobacter baumannii. We also verified association presence extended spectrum β-lactamases, particularly, blaPER-1. Methods: A total 55 were subjected susceptibility testing by disc diffusion method 13 clinically relevant antibiotics. Screening production was done both through tube microtitre plate assay...
ABSTRACT The molecular epidemiology and carbapenem resistance mechanisms of clinical isolates Acinetobacter baumannii obtained from a south Indian tertiary care hospital were investigated by repetitive extragenic palindromic sequence PCR (REP‐PCR) multi‐locus typing (MLST). Analysis resistant determinants was achieved screening for the presence genes encoding OXA‐carbapenemases, metallo‐β‐lactamases (MBLs) efflux pumps. REP‐PCR generated around eight clusters high heterogeneity; these, two...
Inhibition of MurA in open conformation by orientin and closed quercetin-3-<italic>O</italic>-<sc>d</sc>-glucuronide with efficient inhibitory constant values.
Acinetobacter baumannii is an important human pathogen and considered as a major threat due to its extreme drug resistance. In this study, the genome of hyper-virulent MDR strain PKAB07 A. isolated from Indian patient was sequenced analyzed understand mechanisms virulence, resistance evolution. Comparative analysis revealed virulence related genes scattered throughout genome, instead being organized island, indicating highly mosaic nature genome. Many intermittent horizontal gene transfer...
Secretory N-acyl homoserine lactones (AHLs) mediate quorum sensing (QS) in bacteria. AHLs are shown to be inhibitory for an unrelated group of bacteria and might mimic host signalling elements, thereby subverting the regulatory events cells. This study investigated AHL produced by Acinetobacter baumannii analysed its effect on other bacterial species mammalian Chemically characterized had m/z value 325 with a molecular formula C18H31NO4 showed potential against Staphylococcus aureus....
Abstract This study has investigated a total of 51 Acinetobacter baumannii isolates for the prevalence resistant determinants in tigecycline susceptible and non-susceptible clinical A. baumannii. Antimicrobial susceptibility testing revealed 74% were resistant. Mutations RND-efflux pump regulatory genes expression efflux measured isolates. There was strong co-relation between blaNDM-1 armA wherein majority that are positive have also harbored armA. Compared with TSAB (tigecycline baumannii),...
Purpose.: The clinical significance of many species belonging to coagulase-negative staphylococci (CoNS) other than Staphylococcus epidermidis has been increasingly recognized. present study attempted the characterization non–S. CoNS isolates ocular origin. Methods.: were characterized phenotypically by analytical profile index (API) and genotypically fluorescent amplified fragment length polymorphism (FAFLP). In addition, presence genes that are likely enhance virulence such as biofilm...
Staphylococcus aureus is a major human pathogen that also causes important infections in cattle and sheep. The present study aimed to test genetic diversity among strains of S. isolated from (n=34) humans (n=22) by DNA typing.Fluorescent amplified fragment length polymorphism (FAFLP) the genotyping tool used study. presence mecA Panton-Valentine leukocidin (PVL) genes these strain groups was checked.A dendrogram deduced FAFLP showed all clustered into 10 (A-J) with relative divergence less...
Acinetobacter spp. have been found to be responsible for an increasing number of nosocomial infections. During a 16-month period, 22 patients hospitalised mainly in the respiratory intensive care unit (RICU), paediatric and other medical wards were investigated either infection or colonisation by Of 45 isolates detected among total 425 non-fermenters encountered, 24 representative selected extended phenotypic identification. Four environmental also included study. These 28 typed biotyping...
Purpose: Nosocomial infections caused by Acinetobacter species is of increasing concern in critically ill patients, and the risk factors for this infection are not well established. The present investigation was done to determine incidence nosocomial infections. Our study retrospectively attempts find prognostic acquisition infection. Methods: medical records 43 patients with during two-year period (Oct1998-Oct2000) were reviewed involved Acinetobacter. isolates that obtained from these...
Purpose: To detect the presence of autolysin and pneumolysin genes among Streptococcus pneumoniae strains isolated from different disease entities Indian patients. The study also attempted to determine antimicrobial susceptibility isolates. Materials Methods: A total 24 S. isolates were checked for lytA gene coding ply using polymerase chain reaction (PCR). All subjected testing by disc diffusion method 10 therapeutically relevant antibiotics. Minimum inhibition concentration (MIC) was...