A5035616672- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Birth, Development, and Health
- Memory and Neural Mechanisms
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Health, Environment, Cognitive Aging
- Cognitive Abilities and Testing
- Pregnancy and preeclampsia studies
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Attention Deficit Hyperactivity Disorder
- Neural dynamics and brain function
- Child and Adolescent Psychosocial and Emotional Development
- Cognitive Functions and Memory
- Stress Responses and Cortisol
- Neuroscience, Education and Cognitive Function
- Evolutionary Psychology and Human Behavior
- Child and Animal Learning Development
- Advanced Neuroimaging Techniques and Applications
- Aging and Gerontology Research
- Mental Health Research Topics
- Bioinformatics and Genomic Networks
- Paranormal Experiences and Beliefs
University of Oslo
2018-2024
Oslo University Hospital
2024
Norwegian University of Science and Technology
2024
Diakonhjemmet Hospital
2020
Birkbeck, University of London
2018
University College London
2018
Jacobs (United States)
2018
Jacobs Foundation
2018
Royal Society
2018
Lifespan
2014
Human cortical thickness and surface area are genetically independent, emerge through different neurobiological events during development, sensitive to clinical conditions. However, the relationship between changes in two over time is unknown. Additionally, longitudinal studies have almost invariably been restricted older adults, precluding delineation of adult life span trajectories change structure. In this study, we investigated thickness, area, volume after an average interval 3.6 years...
Human fetal development has been associated with brain health at later stages. It is unknown whether growth in utero, as indexed by birth weight (BW), relates consistently to lifespan characteristics and changes, what extent these influences are of a genetic or environmental nature. Here we show remarkably stable lifelong positive associations between BW cortical surface area volume across within developmental, aging longitudinal samples (N = 5794, 4–82 y age, w/386 monozygotic twins,...
Basic perspective taking and mentalizing abilities develop in childhood, but recent studies indicate that the use of social to guide decisions actions has a prolonged development continues throughout adolescence. Here, we aimed replicate this research investigate hypotheses individual differences adolescence are associated with real-life prosocial antisocial behavior brain structure. We used an experimental approach large cross-sectional sample (n = 293) participants aged 7–26 years old...
Human fetal development has been associated with brain health at later stages. It is unknown whether growth in utero, as indexed by birth weight (BW), relates consistently to lifespan characteristics and changes, what extent these influences are of a genetic or environmental nature. Here we show remarkably stable life-long positive associations between BW cortical surface area volume across within developmental, aging longitudinal samples (N = 5794, 4-82 years age, w/ 386 monozygotic twins,...
Human cortical morphology is genetically programmed but also influenced by environment both in development and adulthood. Determining the timing of these influences across lifespan a key challenge. Here we test what makes identical brains differ converge. Mono- (MZ) dizygotic (DZ) twins (n = 206, age 16-79 yrs) with known extent birth weight (BW) discordance, had MRIs pre- post- 10 weeks immersive virtual reality navigation training train-rest-rest/rest-train-rest-design, or as passive...
Detecting errors and adjusting behaviour appropriately are fundamental cognitive abilities that known to improve through adolescence. The neural processes underlying this development, however, still poorly understood. To address knowledge gap, we performed a thorough investigation of error processing in Flanker task cross-sectional sample participants 8 19 years age (n = 98). We examined age-related differences event-related potentials be associated with processing, namely the error-related...
Human cognitive development is manifold, with different functions developing at speeds ages. Attention an important domain of this development, and involves distinct developmental trajectories for separate functions, including conflict processing, selection sensory input alertness. In children, several studies using the Network Test (ANT) have investigated three attentional networks that carry out executive control, orienting alerting. There is, however, a lack on these components across...
Emotional disorders commonly emerge in adolescence, a period characterized by changes emotion-related processes. Thus, the ability to regulate emotions is crucial for well-being and adaptive social functioning during this period. Concurrently, brain undergoes large structural functional changes. We investigated relations between tendencies use two emotion regulation strategies, cognitive reappraisal expressive suppression, development of cerebral cortex subcortical structures (specifically...
Throughout adulthood and ageing our brains undergo structural loss in an average pattern resembling faster atrophy Alzheimer's disease (AD). Using a longitudinal adult lifespan sample (aged 30-89; 2–7 timepoints) four polygenic scores for AD, we show that change AD-sensitive brain features correlates with genetic AD-risk memory decline healthy adults. We first risk links more than expected age early Braak regions, find this extends beyond APOE genotype. Next, run machine learning on...
Human fetal development has been associated with brain health at later stages. It is unknown whether growth in utero, as indexed by birth weight (BW), relates consistently to lifespan characteristics and changes, what extent these influences are of a genetic or environmental nature. Here we show remarkably stable life-long positive associations between BW cortical surface area volume across within developmental, aging longitudinal samples (N = 5794, 4-82 years age, w/ 386 monozygotic twins,...
Prosocial behavior, or voluntary actions that intentionally benefit others, relate to desirable developmental outcomes such as peer acceptance, while lack of prosocial behavior has been associated with several neurodevelopmental disorders. Mapping the biological foundations prosociality may thus aid our understanding both normal and abnormal development, yet how relates cortical development is largely unknown. Here, relations between prosociality, measured by Strengths Difficulties...
Cognitive control enables goal-oriented adaptation to a fast-changing environment and has protracted development spanning into young adulthood. The neurocognitive processes underlying this are poorly understood. In cross-sectional sample of participants 8-19 years old (n = 108), we used blind source separation EEG data recorded in Flanker task derive electrophysiological measures attention conflict processing, including N2-like frontal negative component P3-like parietal positive component....
Human fetal development has been associated with brain health at later stages. It is unknown whether growth in utero, as indexed by birth weight (BW), relates consistently to lifespan characteristics and changes, what extent these influences are of a genetic or environmental nature. Here we show remarkably stable lifelong positive associations between BW cortical surface area volume across within developmental, aging longitudinal samples (N = 5794, 4-82 y age, w/386 monozygotic twins,...
Prosocial behavior, or voluntary actions that intentionally benefit others, relate to desirable developmental outcomes such as peer acceptance, while lack of prosocial behavior has been associated with several neurodevelopmental disorders. Mapping the biological foundations prosociality may thus aid our understanding both normal and abnormal development, yet how relates cortical development is largely unknown. Here, relations between prosociality, measured by Strengths Difficulties...
Abstract Background Neurodevelopmental origins of functional variation through the lifespan are acknowledged, but pathways need to be identified. The objectives project Set‐to‐change is test whether and how early life environmental factors genetic makeup regulate brain cognition its change, as well neurocognitive plasticity in response training lifespan. Method Preliminary analyses for first months presented. We investigate differences their adult mono‐ (MZ) dizygotic (DZ) twins (total n...
Abstract Detecting errors and adjusting behaviour appropriately are fundamental cognitive abilities that known to improve through adolescence. The neural processes underlying this development, however, still poorly understood. To address knowledge gap, we performed a thorough investigation of error processing in Flanker task cross-sectional sample participants 8 19 years age (n = 98). We examined age-related differences event-related potentials be associated with processing, namely the...
Basic perspective taking and mentalising abilities develop in childhood, but recent studies indicate that the use of social to guide decisions actions has a prolonged development continues throughout adolescence. Here, we aimed replicate this research investigate hypotheses individual differences adolescence are associated with real-life prosocial antisocial behavior brain structure. We employed an experimental approach large cross-sectional sample (n=293) participants aged 7-26 years old...
Abstract Across healthy adult life our brains undergo gradual structural change in a pattern of atrophy that resembles accelerated brain changes Alzheimer’s disease (AD). Here, using four polygenic risk scores for AD (PRS-AD) longitudinal lifespan sample aged 30 to 89 years (2-7 timepoints), we show individuals who lose volume faster than expected their age, have higher genetic risk. We first demonstrate PRS-AD associations with early Braak regions, namely hippocampus, entorhinal cortex, and...
Abstract Human fetal development has been associated with brain health at later stages. It is unknown whether growth in utero, as indexed by birth weight (BW), relates consistently to lifespan characteristics and changes, what extent these influences are of a genetic or environmental nature. Here we show remarkably stable life-long positive associations between BW cortical surface area volume across within developmental, aging longitudinal samples (N = 5794, 4-82 years age, w/ 386...
We all make mistakes—and when we do, it is a great opportunity for the brain to adjust what doing and learn. To study how detects deals with errors, researchers have used caps equipped sensors that can measure activity. One thing found using this method creates specific kind of activity person makes mistake. This activity, called error-related negativity or ERN, happens almost at same time error made. It as if already knows are making mistake within fractions second, before even aware it....