A5029683540- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- COVID-19 Clinical Research Studies
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Animal Virus Infections Studies
- Multiple Sclerosis Research Studies
- Genital Health and Disease
- Influenza Virus Research Studies
- vaccines and immunoinformatics approaches
- Animal Disease Management and Epidemiology
- SARS-CoV-2 detection and testing
- Plant Virus Research Studies
- interferon and immune responses
- Immune Cell Function and Interaction
- Hepatitis B Virus Studies
- Cervical Cancer and HPV Research
- Systemic Lupus Erythematosus Research
- Polyomavirus and related diseases
- Bacillus and Francisella bacterial research
- Immune Response and Inflammation
Cyprus Institute of Neurology and Genetics
2006-2022
In order to improve clinical management and prevention of viral infections in hospitalised children improved etiological insight is needed. The aim the present study was assess spectrum respiratory pathogens admitted hospital with acute tract Cyprus. For this purpose nasopharyngeal swab samples from 424 less than 12 years age were collected over three epidemic seasons analysed for presence most common 15 viruses. A pathogen identified 86% samples, multiple being observed almost 20% samples....
Human enteroviruses are responsible for a wide spectrum of clinical diseases affecting many different organ systems. Although infection is usually asymptomatic, infections the central nervous system manifested as meningitis or encephalitis can pose serious public health problem, especially during outbreaks. In this study, samples from 218 patients diagnosed with enteroviral between January 2000 and December 2002 were analysed in order to assess epidemiology human cause viral Cyprus. A new...
Human papillomavirus (HPV) is the most common sexually transmitted agent, and it can cause cervical lesions cancer in females. Currently, information regarding prevalence of HPV Cyprus lacking. The aim this study was to evaluate type-specific 596 women, aged 19–65 years, with cytological abnormalities. Additionally, a subset 348 women for whom cytology results Pap test were available, association between infection disease investigated. detection typing carried out using PCR restriction...
Multiple Sclerosis (MS) is a chronic, demyelinating, inflammatory disease of the central nervous system (CNS) with strong autoimmune component. Several genetic and environmental factors have been suggested to contribute in MS. The Epstein-Barr virus (EBV) one pathogenic candidate proposed be involved onset MS and/or induction subsequent exacerbations. possible involvement EBV highlighted by number national epidemiological studies showing higher percentage seropositivity. This study aims...
Human enteroviruses (HEVs) are responsible for a wide spectrum of clinical diseases. Even though usually associated with non-specific febrile illness, they the most common cause viral meningitis and pose serious public-health problem, especially during outbreaks. Rapid detection identification HEV serotypes in specimens important appropriate patient management epidemiological investigation. A 5 year study (2003-2007) from patients and/or symptoms enteroviral infection was carried out Cyprus...
Whole genome sequencing of viral specimens following molecular diagnosis is a powerful analytical tool epidemiology that can critically assist in resolving chains transmission, identifying new variants or assessing pathogen evolution and allows real-time view into the dynamics pandemic. In Cyprus, first two cases COVID-19 were identified on March 9, 2020 since then 33,567 confirmed 230 deaths documented. this study, whole was performed 133 SARS-CoV-2 positive samples collected between...
An analysis was carried out to determine the presence of enteroviruses and adenoviruses in public swimming pools Cyprus. The effectiveness commonly implemented disinfection procedure chlorination confirmed by determination bacteriological markers. Analysis viral sampling random from five major cities Cyprus during a period 21 months spanning April 2007 December 2008. A 10 l sample taken each pool be tested subsequently concentrated via membrane filtration using new methodological approach...
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) where both environmental and genetic risk factors play role. Among factors, EBV HSV infections have been suggested as strong candidates contributing to MS pathology/progression. Viral recognition control largely tasked NK cells via TLR various cytotoxic immunoregulatory functions. The present work aimed characterize isolated from patients for polymorphisms in gene encoding TLR3, TLR3 important...
The last case of polio in Cyprus caused by a wild-type poliovirus occurred 1995. Since then belongs to the countries considered poliovirus-free WHO. aim this study was confirm absence any circulating polioviruses and monitor vaccine-derived analysis sewages. During course no were identified, although identification viable oral vaccine isolates confirmed presence circulation strains sewage Cyprus.
Abstract Whole genome sequencing of viral specimens following molecular diagnosis is a powerful analytical tool epidemiology that can critically assist in resolving chains transmission, identifying new variants or assessing pathogen evolution and allows real-time view into the dynamics pandemic. In Cyprus, first two cases COVID-19 were identified on March 9, 2020 since then 33,567 confirmed 230 deaths documented. this study, whole was performed 133 SARS-CoV-2 positive samples collected...
The aim of this study was to investigate the epidemiology influenza A virus infection in Cyprus from 2009 pandemic until 2013. Pandemic A(H1N1)2009 infections outnumbered with other respiratory viruses end 2009. also prevalent strain during season 2010-2011; however, it completely replaced by H3N2 subtype next season. During most recent season, 2012-2013, once again only circulating Cyprus. Full-length neuraminidase gene sequencing revealed mutations that had previously been identified as...
The aim of this study was to investigate and obtain insights into the appearance, spread impact Omicron variants their sub-lineages in Cyprus by analyzing 611 high-coverage full-genome sequences for period from November 2021 until April 2022. All viruses sequenced were identified belong either Delta (B.1.617.2) or (lineage BA.1 BA.2, respectively), with a variety different sub-lineages. A detailed analysis mutational profile is presented discussed. variant shortly followed BA.2; despite...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has hit its second year and continues to damage lives livelihoods across the globe. There be a global effort present serological data on SARS-CoV-2 antibodies in different individuals. As such, this study aimed characterize seroprevalence of Cypriot population for first time since started. Our results show that majority people infected with developed IgG against virus, whether anti-NP, anti-S1RBD, or both, at least 20...
There is an ongoing effort to report data on SARS-CoV-2 antibodies in different individuals. Ninety-seven healthcare workers were enrolled this study (Pfizer's BNT162b2, n = 52; and AstraZeneca's ChAdOx1-S, 45) S1RBD-specific IgG analyzed over time. Both vaccines induced after the second dose. A significant increase median levels 3 weeks following dose was detected (BNT162b2, 118.0 BAU/mL 2018.0 BAU/mL; 38.1 182.1 BAU/mL). At months post dose, a decrease also evident 415.6 BAU/mL, 84.7 The...