A5103195955- Cleft Lip and Palate Research
- Obstructive Sleep Apnea Research
- Reconstructive Surgery and Microvascular Techniques
- Craniofacial Disorders and Treatments
- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Tracheal and airway disorders
- Wound Healing and Treatments
- Mesenchymal stem cell research
- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Neuroscience of respiration and sleep
- Facial Nerve Paralysis Treatment and Research
- Oral and Maxillofacial Pathology
- Facial Trauma and Fracture Management
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Spinal Fractures and Fixation Techniques
- Bone fractures and treatments
- Tumors and Oncological Cases
- Airway Management and Intubation Techniques
- Urological Disorders and Treatments
- Traumatic Ocular and Foreign Body Injuries
- Trauma Management and Diagnosis
- Surgical Sutures and Adhesives
Ganesh Shankar Vidyarthi Memorial Medical College
2024-2025
Creative Commons
2016-2023
University of Kansas Medical Center
2020-2023
Children's Hospital of Los Angeles
2019-2022
Apollo Hospitals
2022
University of Kansas
2020
University of Southern California
2020
University of Wisconsin–Madison
2015-2018
Post Graduate Institute of Medical Education and Research
2013-2018
Center For Reconstructive Urethral Surgery
2015-2018
Effective skin regeneration therapies require a successful interface between progenitor cells and biocompatible delivery systems. We previously demonstrated the efficiency of biomimetic pullulan-collagen hydrogel scaffold for improving bone marrow-derived mesenchymal stem cell survival within ischemic wounds by creating "stem niche" that enhances regenerative cytokine secretion. Adipose-derived (ASCs) represent an even more appealing source because their abundance accessibility, in this...
Benign lytic bone lesions, though non-malignant, can cause signicant morbidity if left untreated .These lesions represent approximately 79.3% of musculoskeletal tumors, with a slight female predominance. Surgical intervention is often required to prevent pathological fractures and manage persistent pain or functional impairment .This study investigates the effectiveness hydroxyapatite (G-Bone) mixed grafts (auto graft + GBone) in managing these lesions. Conventional treatment includes...
To investigate how epithelial mechanotransduction pathways impact wound repair.Mechanical forces are increasingly recognized to influence tissue repair, but their role in chronic pathophysiology remains unknown. Studies have shown that wounds exhibit high levels of matrix metalloproteinase 9 (MMP9), a key proteolytic enzyme regulates remodeling. We hypothesized mechanosensory regulated by keratinocyte-specific focal adhesion kinase (FAK) control dermal remodeling via MMP9.A standard model...
Abstract Introduction Unplanned readmissions are associated with decreased healthcare quality and increased costs. This nationwide study examines causes for unplanned readmission among head neck cancer patients undergoing immediate microsurgical reconstruction. Methods Patients tumor resection reconstruction were identified in the 2011–2014 National Surgical Quality Improvement Program database. Clinical characteristics complications compared who did not undergo readmission. Univariate...
Introduction. PriMatrix (TEI Biosciences Inc., Boston, MA, USA) is a novel acellular collagen matrix derived from fetal bovine dermis that designed for use in partial- and full-thickness wounds. This study analyzes the cellular response to vivo, as well ability of this facilitate normal tissue regeneration. Methods. Five by five mm squares rehydrated were implanted subcutaneous fashion on dorsum wild-type mice. Implant site was harvested histology, immunohistochemistry (IHC), flow cytometric...
Radial forearm free flaps are a versatile option for head and neck reconstruction, but often complicated by donor-site problems including skin-graft loss wound breakdown. We introduce the radial "snake" flap as technique enabling primary donor site closure compare healing outcomes to sites requiring split thickness skin graft (STSG) closure.A review of all harvested over 5-year period was performed. identified 18 snake whose were closed primarily. These designed long, narrow ellipse parallel...
Fractures of the bony nasolacrimal system (NLS), including lacrimal sac fossa and canal, have not been comprehensively described in patients with facial trauma. Characterization these injuries may help trauma surgeons better predict which will develop outflow obstruction symptoms epiphora dacryocystitis who eventually need surgery.CT images for all seen at University Wisconsin Hospital Clinics craniofacial were reviewed from January 2001 to December 2005. Patients included if they had a NLS...
Obtaining tissue confirmation of the underlying pathology is gold standard for establishing etiology nontraumatic vertebral compression fractures. However, newer investigative modalities such as magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT) combined potentially offer ability to distinguish between benign malignant lesions, thereby circumventing need invasive diagnostic/biopsy procedures.Twenty-four patients with nontraumatic, spontaneous...
Background Selection of recipient vessels for head and neck microvascular surgery may be limited in the previously dissected or irradiated neck. When distal branches external carotid artery (ECA) are unavailable, additional options arterial inflow needed. Here we propose high ligation ECA transposition toward lower as an alternative. Methods After obtaining institutional approval, patients who underwent tumor resection simultaneous free flap reconstruction were identified over a 5‐year...
Midface hypoplasia dramatically affects the normative facial cascade. Simultaneous Le Fort III and I procedures (Le III/I) provide a powerful tool for achieving significant midface advancement. This study presents authors' approach addressing in setting of class malocclusion using III/I advancement.This was an institutional review board-approved retrospective patients who underwent advancement at institution from 2009 to 2019. Demographic, surgical, postoperative data were recorded. The...
Abstract In late 2019, a novel coronavirus strain, SARS-CoV-2 (severe acute respiratory syndrome 2), also known as disease 2019 (COVID-19), triggered global pandemic the virus spread from Wuhan Province, China, across all continents. Although infrequent, severe infection and death caused by is disproportionately high amongst healthcare providers such craniofacial surgeons who work in head neck region. Factors this impact transmission include: (1) viral loads mucosa of oral nasopharynx, (2)...
Blunt trauma of pancreas in children is uncommon and its management varies from observational to early operative intervention. We analysed the feasibility outcome non-operative all grades paediatric pancreatic injuries.A total 15 patients seen a Paediatric Surgery Unit were retrospectively analyzed.Age ranged 3-11 years (mean, 7.7 years). The mode injury was local 9 children. Only 3 had associated injuries haemodynamically stable. Serum amylase levels raised 12 at admission which 400-1,000...
Elective free flap revision among head and neck cancer patients remains poorly characterized. This study evaluates who underwent their surgical outcomes. Patients tumor extirpation with reconstruction were identified over a 5‐year period. was defined as debulking or redraping of the original for functional cosmetic reasons. Patient demographics, indications, outcomes reviewed. One hundred eighty‐six identified, 19 (10.2%) revision. Revision oral cavity flaps ( n = 9, 47.4%) performed to...
Pterygoid plate fractures are often described in the setting of Le Fort fractures. The goal this study was to define other craniofacial fracture patterns causing injury pterygoid plates. A retrospective review computed tomography (CT) scans obtained on trauma patients over a 5-year period revealed 209 with 78 (37.3%) were unrelated Common causes included sphenotemporal buttress 26 (33.3%), temporal bone 18 (23.1%), zygomaticomaxillary complex 17 (21.8%), and displaced mandible 14 (17.9%)....
Diagnostic tools for evaluating the supraorbital rim in preparation nerve decompression surgery patients with chronic headaches are currently limited. We evaluated use of sonography to diagnose presence a notch or foramen 11 cadaver orbits. Sonographic findings were assessed by dissecting orbits determine whether was present. Sonography correctly diagnosed 7 cases and 4 cases. found that had 100% sensitivity diagnosing foramen. This tool may therefore be helpful characterizing preoperatively...
The Watch Tower Society, the main governing organization of Jehovah's Witness (JW) faith, introduced doctrine to refuse blood in 1945 and has been enforcing it since 1961. A member can be expelled for accepting prohibited components. Many reconstructive surgeries place patients at an increased risk loss. There have attempts reducing rate transfusions craniofacial surgery, even not opposed it.A 15-year-old female patient, who refused transfusion due her presented with a class III...