Abstract Transcranial magnetic stimulation (TMS) was applied to motor areas in the left language‐dominant hemisphere while right‐handed human subjects made lexical decisions on words related actions. Response times referring leg actions (e.g. kick ) were compared with those movements involving arms and hands pick ). TMS of hand influenced processing arm differentially, as documented by a significant interaction factors Stimulation site Word category. Arm area led faster than word responses...

The processing of spoken language has been attributed to areas in the superior temporal lobe, where speech stimuli elicit greatest activation. However, neurobiological and psycholinguistic models have long postulated that knowledge about articulatory features individual phonemes an important role their perception comprehension. To probe possible involvement specific motor circuits speech-perception process, we used event-related functional MRI presented experimental subjects with syllables,...

Hemodynamic and electrophysiological studies indicate differential brain response to emotionally arousing, compared neutral, pictures. The time course source distribution of electrocortical potentials in emotional stimuli, using a high‐density electrode (129‐sensor) array were examined here. Event‐related (ERPs) recorded while participants viewed pleasant, unpleasant ERP voltages six intervals, roughly corresponding P1, N1, early P3, late P3 slow wave window. Differential activity was found...

Single words and sentences referring to bodily actions activate the motor cortex. However, this semantic grounding of concrete language does not address critical question whether sensory–motor system contributes processing abstract meaning thought. We examined functional magnetic resonance imaging activation idioms literal including arm- leg-related action words. A common left fronto-temporal network was engaged in sentence reading, with yielding relatively stronger activity (pre)frontal...

The human visual system is an intricate network of brain regions that enables us to recognize the world around us. Despite its abundant lateral and feedback connections, object processing commonly viewed studied as a feedforward process. Here, we measure model rapid representational dynamics across multiple stages ventral stream using time-resolved imaging deep learning. We observe substantial transformations during first 300 ms within ventral-stream regions. Categorical divisions emerge in...

Abstract It has been suggested that the processing of action words referring to leg, arm, and face movements (e.g., kick, pick, lick) leads distinct patterns neurophysiological activity. We addressed this issue using multi‐channel EEG beam‐former estimates distributed current sources within head. The categories leg‐, arm‐, face‐related were carefully matched for important psycholinguistic factors, including word frequency, imageability, valence, arousal, evaluated in a behavioral study their...

Noise-normalization has been shown to partly compensate for the localization bias towards superficial sources in minimum norm estimation. However, it argued that order make inferences case of multiple sources, properties alone are insufficient. Instead, measures resolution should be applied both point-spread and cross-talk functions (PSFs CTFs). Here, we demonstrate noise-normalization affects shapes PSFs, but not CTFs. We evaluated PSFs CTFs MNE, dSPM sLORETA inverse operators, on metrics...

Abstract Mismatch negativity (MMN), an index of experience‐dependent memory traces, was used to investigate the processing action‐related words in human brain. Responses auditorily presented movement‐related English were recorded a non‐attend odd‐ball protocol using high‐density electroencephalographic (EEG) set‐up. MMN calculated responses same as standard and deviant stimuli different sessions avoid contamination from phonetic–acoustic differences. The topography mismatch action revealed...

Sensorimotor areas activate to action- and object-related words, but their role in abstract meaning processing is still debated. Abstract emotion words denoting body internal states are a critical test case because they lack referential links objects. If actions expressing crucial for learning correspondences between word forms emotions, word–evoked activity should emerge motor brain systems controlling the face arms, which typically express emotions. To this hypothesis, we recruited 18...

The embodied cognition framework suggests that neural systems for perception and action are engaged during higher cognitive processes. In an event-related fMRI study, we tested this claim the abstract domain of numerical symbol processing: is human cortical motor system part representation numbers, organization knowledge influenced by individual finger counting habits? Developmental studies suggest a link between numerals habits due to acquisition skills through in childhood. present digits...

Abstract Concepts are composed of features related to different sensory and motor modalities such as vision, sound, action. It is a matter controversy whether conceptual represented in sensory-motor areas reflecting the specific learning experience during acquisition. In order address this issue, we assessed plasticity representations by training human participants with novel objects under conditions. These were assigned categories that for one class categories, overall shape was diagnostic...

We usually feel that we understand a familiar word "immediately". However, even basic aspects of the time-line recognition are still controversial. Different domains research have not converged on coherent account. An integration multiple sources information would lead to more strongly constrained theoretical models, and help finding optimal measures when monitoring specific impairments in patient groups. In our multimodal approach--combining fast behavioral measures, ERPs EEG/MEG source...

The time course of brain activation during word production has become an area increasingly intense investigation in cognitive neuroscience. predominant view been that semantic and phonological processes are activated sequentially, at about 150 200–400 ms after picture onset. Although evidence from prior studies interpreted as supporting this view, these were arguably not ideally suited to detect early processes. We here used a multiple linear regression approach magnetoencephalography (MEG)...

Semantic knowledge is based on the way we perceive and interact with world. However, jury still out question: to what degree are neuronal systems that subserve acquisition of semantic knowledge, such as sensory-motor networks, involved in its representation processing? We will begin a critical evaluation main behavioral neuroimaging methods respect their capability define functional roles specific brain areas. Any or neuroscientific measure conflation representations processes. Hence,...

There is growing interest in the rich temporal and spectral properties of functional connectome brain that are provided by Electro- Magnetoencephalography (EEG/MEG). However, problem leakage between sources arises when reconstructing activity from EEG/MEG recordings outside head makes it difficult to distinguish true connections spurious connections, even based on measures ignore zero-lag dependencies. In particular, standard anatomical parcellations for potential cortical tend over- or...

The spatial resolution of EEG/MEG source estimates, often described in terms leakage the context inverse problem, poses constraints on inferences that can be drawn from estimation results. Software packages for data analysis offer a large choice methods but few tools to experimental researchers evaluation and comparison. Here, we describe framework objective intuitive based linear systems analysis, apply those most widely used distributed such as L2-minimum-norm (L2-MNE) linearly constrained...

Using a speeded lexical decision task, event-related potentials (ERPs), and minimum norm current source estimates, we investigated early spatiotemporal aspects of cortical activation elicited by words pseudo-words that varied in their orthographic typicality, is, the frequency component letter pairs (bi-grams) triplets (tri-grams). At around 100 msec after stimulus onset, ERP pattern revealed significant typicality effect, where with atypical orthography (e.g., yacht, cacht) stronger brain...

To investigate the cortical basis of color and form concepts, we examined event-related functional magnetic resonance imaging (fMRI) responses to matched words related abstract information. Silent word reading elicited activity in left temporal frontal cortex, where category-specific differences were also observed. Whereas preferentially activated anterior parahippocampal gyrus, evoked fusiform middle gyrus as well premotor dorsolateral prefrontal areas inferior gyri. These results...