- Spinal Fractures and Fixation Techniques
- Pelvic and Acetabular Injuries
- Spine and Intervertebral Disc Pathology
- Hip and Femur Fractures
- Medical Imaging and Analysis
- Poisoning and overdose treatments
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Pain Management and Treatment
- Bone health and osteoporosis research
- Musculoskeletal pain and rehabilitation
- Infectious Diseases and Tuberculosis
- Orthopedic Infections and Treatments
- Craniofacial Disorders and Treatments
- Radiology practices and education
- Healthcare Systems and Public Health
- Cerebrospinal fluid and hydrocephalus
- Medical and Health Sciences Research
- Musculoskeletal Disorders and Rehabilitation
- Intracerebral and Subarachnoid Hemorrhage Research
- Spinal Hematomas and Complications
- Myofascial pain diagnosis and treatment
- Management of metastatic bone disease
- Hedgehog Signaling Pathway Studies
- Genetic Neurodegenerative Diseases
Jena University Hospital
2015-2024
Friedrich Schiller University Jena
1999-2024
The Tavistock and Portman NHS Foundation Trust
1999
The complication rate for cranioplasty after decompressive craniectomy is higher than that other neurosurgical procedures; aseptic bone resorption the major long-term problem. Patients frequently need additional operations to remove necrotic and replace it with an artificial substitute. Initial implantation of a substitute may be option selected patients who are at risk resorption, but this cohort has not yet been clearly defined. authors' goals were identify factors flap necrosis define...
Abstract Introduction The assessment of bone density has gained significance in recent years due to the aging population. Accurate is crucial when deciding on appropriate treatment plan for spinal stabilization surgery. objective this work was determine trabecular values subaxial cervical, thoracic and lumbar spine using Hounsfield units. Material methods Data from 200 patients who underwent contrast-enhanced polytrauma computed tomography at a maximum care hospital over two-year period were...
Intracerebral hemorrhage (ICH) is a life threatening entity, and an early outcome assessment mandatory for optimizing therapeutic efforts.We retrospectively analyzed data from 342 patients with spontaneous primary ICH to evaluate possible predictors of 30-day mortality considering clinical, radiological, therapeutical parameters. We also applied three widely accepted grading scoring systems [(ICH score, FUNC score intracerebral scale (ICH-GS)] on our population the correlation these scores...
The assessment of bone density is great importance nowadays due to the increasing age patients. Especially in regard surgical stabilization spine, important for therapeutic decision making. aim this work was record trabecular values using Hounsfield units second cervical vertebra.The study a monocentric retrospective data analysis 198 patients who received contrast-enhanced polytrauma computed tomography period two years at maximum care hospital. were measured three different regions within...
The incidence of pyogenic spondylodiscitis is increasing, and the disease associated with considerable morbidity, mortality, long-term healthcare utilization societal costs. Disease-specific treatment guidelines are lacking there little consensus regarding optimal conservative surgical management. This cross-sectional survey German specialist spinal surgeons sought to determine practice patterns degree management lumbar (LPS). An electronic covering provider information, diagnostic...
Abstract Aim Osteoporotic thoracolumbar fractures are of increasing importance. To identify the optimal treatment strategy this multicentre prospective cohort study was performed. Purpose Patients suffering from osteoporotic were included. Excluded tumour diseases, infections and limb fractures. Age, sex, trauma mechanism, OF classification, OF-score, strategy, pain condition mobilization analysed. Methods A total 518 patients’ aged 75 ± 10 (41–97) years included in 17 centre. 174 patients...
Multicenter prospective cohort study.The study aims to validate the recently developed OF score for treatment decisions in patients with osteoporotic vertebral compression fractures (OVCF).This is a multicenter (EOFTT) 17 spine centers. All consecutive OVCF were included. The decision conservative or surgical therapy was made by treating physician independent of recommendation. Final compared recommendations given score. Outcome parameters complications, Visual Analogue Scale, Oswestry...
Abstract Introduction Vertebral fractures in patients with bone density reduction are often a major challenge for the surgeon, as reduced can lead to screw loosening. Several options available determine preoperatively. In our study, we investigated correlation of Hounsfield units (HU) contrast medium computed tomography (CT) values quantitative (QCT) and formula estimate using HU. Materials methods retrospective data analysis, examine 98 vertebral bodies from 35 who received CT spine QCT,...
Multicenter prospective cohort study.To analyse therapeutical strategies applied to osteoporotic thoracolumbar OF 4 injuries, assess related complications and clinical outcome.A multicenter study (EOFTT) including 518 consecutive patients who were treated for an Osteoporotic vertebral compression fracture (OVCF). For the present study, only with fractures analysed. Outcome parameters complications, Visual Analogue Scale, Oswestry Disability Questionnaire, Timed Up & Go test, EQ-5D 5L,...
Subgroup analysis of a multicenter prospective cohort study.To analyse surgical strategies applied to osteoporotic thoracolumbar fracture (OF) 5 injuries with anterior or posterior tension band failure and assess related complications clinical outcome.A study (EOFTT) was conducted at 17 spine centers including 518 consecutive patients who were treated for an vertebral (OVF). For the present study, only OF fractures analysed. Outcome parameters complications, Visual Analogue Scale (VAS),...
This study examined the efficacy of computed tomography (CT)-based Hounsfield units (HU) as early predictors aseptic bone necrosis, a serious post-cranioplasty complication after autologous cranioplasty. In total, 100 patients who underwent decompressive craniectomy and subsequent cranioplasty were included. The radiodensity flap was evaluated in HU from CT scans at five follow-up timepoints. thresholds established to predict development necrosis. demonstrated declining trend throughout...
The incidence of spondylodiscitis has witnessed a significant increase in recent decades. Surgical intervention becomes necessary case bone destruction to remove infected tissue and restore spinal stability, often involving the implantation cage. Despite appropriate treatment, relapses occur up 20 percent cases, resulting substantial economic social burdens. formation biofilm been identified as major contributor relapse development. Currently, there is no consensus among German-speaking...
The aim of our study was to identify factors that influence the occurrence adjacent fractures in patients with cement-augmented pedicle screw instrumentation.Data were retrospectively collected from medical charts and operative reports for every surgery which instrumentation used hospital 4 consecutive years. A total 93 operations included examined gender, age, T-score, number fused segments, implanted screws, broken loosening leakage distribution pattern cement, pre- postoperative kyphosis...
Study Design Multicenter prospective cohort study. Objectives Anxiety in combination with osteoporotic vertebral compression fractures (OVCFs) of the spine remains understudied. The purpose this study was to analyze whether anxiety has an impact on short-term functional outcome patients OVCF. Furthermore, a direct fracture patient’s during hospitalization should be recognized. Methods All inpatients OVCF thoracolumbar from 2017 2020 were included. Trauma mechanism, analgetic medication,...
Osteoporotic vertebral fractures are a major healthcare problem. Vertebral cement augmentation (VCA) is frequently used as minimally invasive surgical approach to manage symptomatic fractures. However, there potential risk of adjacent segment fracture (ASF), which may require second surgery. The addition transcutaneous screw-fixation with superior and inferior the [Hybrid screw fixation (HTSF)] might represent an alternative treatment option reduce incidence ASF.We retrospectively compared...
Despite the proven effectiveness of simulation-based learning in medical education, realm neurosurgery lacks dedicated instructional platforms, particularly those engaging learner critical decisionmaking scenarios.This shortfall creates a challenging environment for students transitioning to clinical environment, where they may encounter acute neurosurgical presentations or complex ward management dilemmas, with limited prior experience.