Abstract Flood is one of the most common natural disasters, which also triggers other disasters such as erosion and landslides. damage can be minimised by ensuring optimum design drainage infrastructure flood management tasks, depends largely on reliable estimation quantiles. This study investigates quantile in ungauged catchments using a kriging-based regional frequency analysis (RFFA) technique. Three main research objectives are addressed this study. Firstly, RFFA models developed 558...

Ventricular assist devices (VADs) are a life-saving form of mechanical circulatory support in heart failure patients. However, VADs have not yet reached their full potential due to the associated side effects (thrombosis, bleeding, infection) related activation and damage blood cells proteins caused by stress foreign materials. Studies on leukocytes limited, leukocyte including microparticle generation can influence both thrombosis infection rates. Therefore, aim was develop multicolor flow...

The American Society for Testing and Materials (ASTM) F1841 standard the assessment of hemolysis in blood pumps recommends using phosphate-buffered saline (PBS) hemodilution to standardize hematocrit (HCT). However, PBS increases red cell mechanical fragility hemolysis. Herein, we investigated diluents dilutions during vitro testing reduce bias when assessing Bovine was diluted with either or + 4/6 g% bovine serum albumin (BSA) a 70/90% dilution, an HCT 30% ± 2%, pumped CentriMag RotaFlow...

There is growing evidence by the literature that unbalance between androgens and estrogens a relevant condition associated with common canine reproductive disorder known as cryptorchidism. The role of in regulating testicular cell function events supposedly due to wide expression two nuclear estrogen receptors (ERs), ER-alpha ER-beta trans-membrane G protein-coupled receptor (GPER) testis. In this study, immunohistochemistry, Western blotting qRT-PCR were used assess distribution GPER...

Heart failure, a common clinical syndrome caused by functional and structural abnormalities of the heart, affects 64 million people worldwide. Long-term mechanical circulatory support can offer lifesaving treatment for end-stage systolic heart failure patients. However, this is not without complications. This review covers major complications associated with implantable devices, including strokes, pump thrombosis gastrointestinal bleeding. These were assessed in patients implanted following...

Peptic ulcer disease (PUD) is a major global health concern that often results in hospitalization due to insufficient protective factors the mucosa. Helicobacter pylori contributes PUD development, causing symptoms such as epigastric pain, bloating, fullness, and nausea. An extensive literature search was conducted using electronic databases PubMed Google Scholar identify articles published between 2013 2024. Relevant cross-sectional studies, systematic reviews, meta-analyses, case reports...

Urocortin (UCN), a 40 amino acid peptide, is corticotrophin-releasing hormone (CRH)-related peptide. The biological actions of CRH family peptides are mediated via two types G-protein-coupled receptors, type 1 (CRHR1) and 2 (CRHR2). aim this study was to investigate the expression UCN, CRHR1 CRHR2 by immunoprecipitation, Western blot, immunohistochemistry RT-PCR in bovine thyroid gland. Immunoprecipitation blot analysis showed that tissue extracts reacted with anti-UCN, anti-CRHR1 anti-CRHR2...

Alpacas (Vicugna pacos) are domesticated camelids indigenous to south America and recently also bred in Europe Italy for their high quality wool. There is little data available regarding the innervation of male reproductive tract this species. In present study, distribution protein gene product 9.5 (PGP 9.5), neuropeptide Y (NPY), tyrosine hydroxilase (TH), calcitonin related peptide (CGRP) substance P (SP) was analyzed epididymis by using immunohistochemical methods. Specimens caput, corpus...

Based on the improvement of Crohn's disease (CD) with elemental diets, we treated a patient recurrent stenosing using prednisolone and drastic reduction oral lipid intake. Complete symptomatic good radiological took place. A newly proposed hypothesis for CD suggests that enteral lipids together certain luminal bacterial fragments become strongly antigenic to produce an inflammatory reaction analogous adjuvant response. Because apparent success dietary exclusion in this patient, suggest it be...

Abstract Cryptorchidism is associated with changes in the gonads and spermatic duct system, which may cause infertility problems. Urocortin (UCN) a corticotrophin‐releasing hormone (CRH)‐related peptide, affects several functions of male genital organs. The aim present study was to investigate expression UCN its receptors CRHR1 CRHR2 using immunohistochemistry, western blotting real‐time reverse transcription polymerase chain reaction tissues collected from epididymis normal cryptorchid...

Background: Mechanical circulatory support (MCS) causes high levels of shear stress, which could lead to complications such as platelet activation and thrombosis. Aspirin is an anti-platelet drug that functions through COX-1 inhibition, however, this may not be sufficient reduce via mechanical stimuli. As such, study evaluated the efficiency downstream effects functioning impact have on stress-induced Methods: Human blood was treated with without (4.5 μg/mL) subjected VAD-like stress for 4...