Paolo Brusini

ORCID: 0000-0003-0855-5775
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About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Corneal surgery and disorders
  • Retinal Imaging and Analysis
  • Retinal Diseases and Treatments
  • Ophthalmology and Eye Disorders
  • Corneal Surgery and Treatments
  • Intraocular Surgery and Lenses
  • Ocular Surface and Contact Lens
  • Ophthalmology and Visual Impairment Studies
  • Retinal Development and Disorders
  • Retinal and Optic Conditions
  • Cerebral Venous Sinus Thrombosis
  • Ocular Infections and Treatments
  • Neurological Disorders and Treatments
  • Retinal and Macular Surgery
  • Ocular Oncology and Treatments
  • Cerebrospinal fluid and hydrocephalus
  • Optical Coherence Tomography Applications
  • Sympathectomy and Hyperhidrosis Treatments
  • Proteoglycans and glycosaminoglycans research
  • Nasolacrimal Duct Obstruction Treatments
  • Infrared Thermography in Medicine
  • Ocular and Laser Science Research
  • Optical Imaging and Spectroscopy Techniques
  • Gaze Tracking and Assistive Technology

University of Udine
2008-2023

Universidad de Londres
2021

Dalhousie University
2021

City, University of London
2021

University of Milan
2021

Hôpital d'Instruction des Armées Bégin
2021

Fondazione G.B. Bietti
2021

Nova Scotia Health Authority
2021

Ospedale Santa Maria della Misericordia di Udine
2007-2017

Ophthalmology Associates (United States)
2007-2012

To introduce a new method, derived from the Glaucoma Staging System (GSS), for classifying glaucomatous visual field defects.Four sample groups composed respectively of 471 (sample #1), 128 #2), 185 #3), and 131 #4) patients with either ocular hypertension or chronic glaucoma were considered. The GSS 2 uses both MD CPSD/CLV PSD/LV perimetric indices to classify defect in 6 stages 3 types (generalized, localized, mixed). formulas determined using #1. A borderline stage was created, on basis...

10.1097/01.ijg.0000195932.48288.97 article EN Journal of Glaucoma 2005-12-23

Purpose To compare the intraocular pressure (IOP) readings taken with new ICare tonometer and Goldmann applanation (GAT) to evaluate influence of central corneal thickness (CCT) on IOP measurements. Patients Methods One eye 178 consecutive patients primary open-angle glaucoma underwent ultrasonic CCT measurement, followed by evaluation GAT tonometer. The deviation from values, corrected according Doughty Zaman formula, was calculated correlated a linear regression model. agreement between 2...

10.1097/01.ijg.0000212208.87523.66 article EN Journal of Glaucoma 2006-06-01

To investigate short-term effect on intraocular pressure (IOP) after intravitreal injection of ranibizumab (Lucentis) (IVIL).This prospective study included 1 eye 54 patients (64+/-12 y) with wet age-related macular degeneration treated IVIL. IOP measurements TonoPen were taken: immediately before and 5 seconds, 5, 10, 15, 30, 60 minutes, day Axial length (with ultrasound biometry) was assessed in 24 eyes. The analysis difference at various time points between phakic pseudophakic eyes the...

10.1097/ijg.0b013e31819c4893 article EN Journal of Glaucoma 2009-12-01

To evaluate precision and accuracy of Corvis-ST, a new noncontact tonometer equipped with high-speed Scheimpflug technology, which measures intraocular pressure (IOP), central corneal thickness (CCT), deformation parameters (CDPs). Relationships among IOP, CCT, CDPs were also assessed.This prospective, randomized study included 1 eye 164 subjects (79 controls 85 glaucoma patients), underwent IOP measurements taken 3 times Goldmann applanation tonometry (GAT) Corvis-ST in random order....

10.1097/ijg.0000000000000133 article EN Journal of Glaucoma 2014-10-15

Canaloplasty is a new nonperforating surgical technique for open-angle glaucoma, in which microcatheter inserted within Schlemm’s canal the entire 360 degrees. A 10-0 prolene suture, tied to distal tip of microcatheter, then positioned and left tensioned canal, thus facilitating aqueous outflow through natural pathways. small amount viscoelastic agent delivered while catheter withdrawn. The mid-term results are very promising. Based on our cohort 214 patients, percentages eyes that obtained...

10.1155/2014/469609 article EN cc-by The Scientific World JOURNAL 2014-01-01

This new method, based on the use of MD and CPSD (or CLV) visual field indices, can instantly classify not only stage glaucomatous damage, but also type defect (localized, generalized or mixed). system was used to study defects in 500 automated tests, performed with either Humphrey 30-2 Octopus G1 threshold tests. The most common found were mixed, purely local very unusual, especially advanced glaucoma.

10.1177/112067219600600411 article EN European Journal of Ophthalmology 1996-10-01

Abstract. Purpose: To compare intraocular pressure (IOP) measurements taken with Pascal dynamic contour tonometry (DCT), the TonoPen and Goldmann applanation (GAT). The influence of central corneal thickness (CCT) on IOP DCT was evaluated. Methods: One eye in each 101 consecutive patients primary open‐angle glaucoma (POAG) underwent ultrasonic CCT measurement evaluation GAT, random order. agreement between results from those GAT assessed using Bland−Altman method. deviation readings values,...

10.1111/j.1600-0420.2006.00834.x article EN Acta Ophthalmologica Scandinavica 2006-11-27

Adipose-derived stem cells (ADSC) are multipotent, safe, non-immunogenic and can differentiate into functional keratocytes in situ. The topical use of ADSC derived from human processed lipoaspirate was investigated for treating injured rat cornea.A total 19 rats were used. Six animals initially underwent corneal lesion experiments with 0.5 N NaOH (right eye) 0.2 (left). protocol then used 13 rats. All 26 eyes received azythromycin bid 3 d divided five treatment groups (n = 5 eyes/group),...

10.3109/02713683.2012.763100 article EN Current Eye Research 2013-02-01

The aim of our study was to assess the clinical effectiveness topical adipose derived stem cell (ADSC) treatment in laser induced corneal wounds mice by comparing epithelial repair, inflammation, and histological analysis between arms. Corneal lesions were performed on both eyes 40 photorefractive keratectomy. All treated with azythromycin bid for three days. Mice divided groups (n = 20), which included: control, cells basic serum; received times daily five consecutive Biomicroscope...

10.3390/jcm6120115 article EN Journal of Clinical Medicine 2017-12-05

Purpose To assess the Humphrey Matrix 30-2 test in detecting functional glaucomatous damage. Patients and Methods One eye each of 60 healthy individuals, 108 patients with ocular hypertension (OHT), 150 preperimetric (48) or perimetric (102) high-tension primary open-angle glaucoma (POAG) were considered. Visual fields assessed by standard automated perimetry (SAP) Field Analyzer 30-2, frequency doubling technology (FDT) N-30, tests. Significantly abnormal points pattern deviation...

10.1097/00061198-200604000-00001 article EN Journal of Glaucoma 2006-04-01

To compare central corneal thickness (CCT) and endothelial cell density (ECD) with laser scanning confocal microscope Heidelberg Retina Tomograph (HRT) II Rostock Corneal Module noncontact specular Tomey EM-3000 to assess intra- interobserver agreement in normal corneas.This prospective study included 48 normals (69.6 ± 7.2 years, range: 55-80 years) who underwent CCT ECD both HRT 3 times by 2 independent observers. Measurement differences between instruments, devices, test-retest...

10.1097/ico.0b013e3182000c5d article EN Cornea 2010-12-10

Tight control of intraocular pressure (IOP) is still the only therapeutic approach available for treatment primary open angle glaucoma (POAG). However, some patients do not respond adequately to hypotonising drugs, and despite multiple drug combinations they cannot reach their target IOP. Forskolin a natural compound that has already shown efficacy in IOP reduction following topical application.The aim this study was evaluate effects on food supplement containing forskolin rutin when...

10.1089/jop.2012.0021 article EN Journal of Ocular Pharmacology and Therapeutics 2012-06-27

To evaluate the effectiveness of ab-interno microcatheterization and 360° viscodilation Schlemm's canal (SC) performed with OMNI viscosurgical system in open angle glaucoma (OAG) together or not phacoemulsification.Two surgical sites.Retrospective, observational.Eighty eyes from 73 patients mild to moderate OAG underwent ab- interno SC system. Fifty (Group 1) only viscodilation, while 30 2) surgery + cataract extraction. Primary success endpoint at 12 months was an intraocular pressure (IOP)...

10.3390/jcm11010259 article EN Journal of Clinical Medicine 2022-01-04

Frequency-doubling perimetry (FDP) is a new, out-of-the-ordinary, visual field testing method. Its sensitivity and reliability was tested in 16 patients (32 eyes) with ocular hypertension 21 (37 early chronic glaucoma. Significant defects were found almost 10% of hypertensive eyes 67.7% glaucomatous eyes. FDP an effective sensitive technique for glaucoma functional loss assessment.

10.1111/j.1600-0420.1998.tb00869.x article EN Acta Ophthalmologica Scandinavica 1998-12-01

Abstract. Purpose: To compare the abilities of scanning laser polarimetry with variable corneal compensator (GDx VCC) those optical coherence tomography (Stratus OCT) in discriminating between healthy and early‐to‐moderate perimetric glaucomatous eyes. Methods: A total 95 patients (mean deviation − 3.7 ± 3.0 dB, pattern standard 4.5 2.7 dB) 62 control subjects underwent imaging by GDx VCC Stratus OCT using both optic nerve head (ONH) retinal fibre layer (RNFL) scan protocols. One eye per...

10.1111/j.1600-0420.2006.00747.x article EN Acta Ophthalmologica Scandinavica 2006-08-03

<h3>Aim</h3> To assess the epithelial features of bulbar conjunctiva using in vivo confocal microscopy patients with glaucoma undergoing canaloplasty. <h3>Methods</h3> Thirty consecutive were enrolled. Canaloplasty was considered successful if preoperative intraocular pressure (IOP) reduced by one-third. The examined laser-scanning 1 week before (baseline) and 12 weeks after surgery. mean density (MMD, cysts/mm<sup>2</sup>) area (MMA, μm<sup>2</sup>) conjunctival microcysts IOP measured....

10.1136/bjophthalmol-2011-301058 article EN British Journal of Ophthalmology 2012-01-31

Objective To assess the accuracy of probabilistic deep learning models to discriminate normal eyes and with glaucoma from fundus photographs visual fields. Design Algorithm development for discriminating using data multicenter, cross-sectional, case-control study. Subjects participants Fundus photograph field 1,655 929 subjects develop test an independent group 196 98 patients validate models. Main outcome measures Accuracy area under receiver-operating characteristic curve (AUC). Methods...

10.3389/fmed.2022.923096 article EN cc-by Frontiers in Medicine 2022-09-29
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