A5017509513- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Surgical Treatments
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Gastroesophageal reflux and treatments
- Gastrointestinal disorders and treatments
- Diverticular Disease and Complications
- Dysphagia Assessment and Management
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Treatments and Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Inflammatory Bowel Disease
- Radiomics and Machine Learning in Medical Imaging
- Eosinophilic Esophagitis
- Pancreatic and Hepatic Oncology Research
- Cardiac, Anesthesia and Surgical Outcomes
- Appendicitis Diagnosis and Management
- AI in cancer detection
- Helicobacter pylori-related gastroenterology studies
- Biliary and Gastrointestinal Fistulas
- Hemostasis and retained surgical items
King's College Hospital
2016-2025
King's College Hospital NHS Foundation Trust
2015-2025
The Japanese Society of Gastroenterological Surgery
2023-2024
Iwate Medical University
2023-2024
Onomichi General Hospital
2023-2024
Hiroshima University
2023-2024
King's College London
2017-2023
Hiroshima University Hospital
2023
Hudson Institute
2023
The King's College
2018-2021
The safety of peroral endoscopic myotomy (POEM) is still debated since comprehensive analysis adverse events (AEs) associated with the procedure in large multicenter cohort studies has not been performed. To study (1) prevalence AEs and (2) factors occurrence patients undergoing POEM.Patients who underwent POEM at 12 tertiary-care centers between 2009 2015 were included this case-control study. Cases defined by any AE related to procedure. Control selected for each case matching age, gender,...
Abstract Background and study aims The variables associated with gastroesophageal reflux (GER) after peroral endoscopic myotomy (POEM) are largely unknown. This aimed to: 1) identify the prevalence of esophagitis asymptomatic GER in patients who underwent POEM, 2) evaluate patient intraprocedural post-POEM GER. Patients methods All POEM subsequent objective testing for (pH or without upper gastrointestinal [GI] endoscopy) at seven tertiary academic centers (one Asian, two US, four European)...
Abstract Background and study aims Decisions concerning additional surgery after endoscopic resection of T1 colorectal cancer (CRC) are difficult because preoperative prediction lymph node metastasis (LNM) is problematic. We investigated whether artificial intelligence can predict LNM presence, thus minimizing the need for surgery. Patients methods Data on 690 consecutive patients with CRCs that were surgically resected in 2001 – 2016 retrospectively analyzed. divided into two groups...
The efficacy of per oral endoscopic myotomy (POEM) in non-achalasia esophageal motility disorders such as esophagogastric junction outflow obstruction (EGJOO), diffuse spasm (DES), and jackhammer esophagus (JE) has not been well demonstrated. aim this international multicenter study was to assess clinical outcomes POEM patients with disorders, namely DES, JE, EGJOO, a large cohort patients.This retrospective at 11 centers. Consecutive who underwent for or JE between 1/2014 9/2016 were...
BACKGROUND: Artificial intelligence using computer-aided diagnosis (CADx) in real time with images acquired during colonoscopy may help colonoscopists distinguish between neoplastic polyps requiring removal and nonneoplastic not removal. In this study, we tested whether CADx analyzed helped decision-making process. METHODS: We performed a multicenter clinical study comparing novel CADx-system that uses real-time ultra-magnifying polyp visualization standard visual inspection of small (≤5 mm...
Aim Reduced hospital stay confers clinical and economic benefits for patients healthcare providers. This article examines the length of consequent bed resource usage undergoing elective excisional colorectal surgery in English NHS trusts. Method All resections malignancy between 1996 2006 trusts were included from Hospital Episode Statistics data set. Unifactorial multifactorial analyses performed to identify independent predictors prolonged 28-day readmission. Results Over 10-year period,...
Objective Endoscopic submucosal dissection (ESD) in a curative intent for submucosa-invasive early (T1) colorectal cancers (T1-CRCs) often leads to subsequent surgical resection case of histologic parameters indicating higher risk nodal involvement. In some cases, however, the expected benefit may be offset by risks, suggesting more conservative approach. Design Retrospective analysis consecutive patients with T1-CRC who underwent ESD at 13 centres ending inclusion 2019 (n=3373). Cases high...
A retrospective analysis was conducted comparing open and percutaneous repair of ruptured Achilles tendon, over a 14-year period. One hundred eight patients were identified; 70 underwent traditional 38 had modified Ma & Griffith repair. The mean operating time with 28.5 minutes compared to 45.9 in the group ( p = < .0001). Comparable results obtained subjective range movement, stiffness, power both groups at discharge from clinic. In there four cases rerupture (5.7%), deep infections...
This study was primarily aimed to quantify perioperative mortality risk in elderly patients undergoing elective colonic resectional surgery. In addition, the safety of minimally invasive surgery this patient group evaluated.All aged > 75 resection for colorectal malignancy between 1996 and 2007 English NHS hospitals were included from Hospital Episode Statistics (HES) dataset.Between dates, 28,746 years underwent resection. The national annual number excisions carried out amongst increased...
We report an unusual case of strangulated diaphragmatic (Morgagni) hernia resulting in ischaemia the small and large bowel, which was initially diagnosed as a pneumonia. This highlights importance being aware this rare, but potentially fatal condition when assessing patients with respiratory symptoms abdominal pain.
Background and study aims Per-oral endoscopic myotomy (POEM) is associated with a short-term clinical response of 82 % to 100 in treatment patients achalasia. Data are limited on the long-term durability these patients. The aim this was determine outcomes undergoing POEM for management Methods This retrospective multicenter cohort consecutive who underwent Patients had minimum 4 years follow-up. Clinical defined by an Eckardt score ≤ 3. Results A total 146 were included from 11 academic...
Abstract Aims Diverticular disease (DD) is highly prevalent. Management largely targets complications with surgical intervention frequently used in recurrent, complicated disease. DD poses a significant burden on healthcare systems, warranting thorough cost-analysis for informed resource allocation and policy decisions. Current UK data the cost of lacking. We aim to establish at tertiary referral centre. Methods Data were collected retrospectively from our centre between 2012 2021....
Background Computer-aided diagnosis (CADx) enables the distinction between neoplastic and non-neoplastic polyps during colonoscopy. We aimed to estimate patient-level benefit harm of CADx. Methods conducted a comparative analysis on data from EndoBRAIN international clinical trial, evaluating effect optical colonoscopy with without Three hypothetical scenarios were compared: “endoscopist-alone” “CADx-assisted” leave-in-situ strategies (leaving rectosigmoid ≤ 5 mm), “total removal” (removing...
Magnification endoscopy enables in vivo evaluation of gastrointestinal mucosa. Furthermore, endocytoscopy (ECS) with ultra-high magnification observation cellular atypia during routine endoscopic examination. The purpose this study is to clarify the efficacy ECS and endocytoscopic (ECA) classification various types benign malignant pathology esophagus. Consecutive 110 patients, who underwent our institution from March 2003 December 2009, were included study. One hundred forty-six esophageal...