Erkan Güler

ORCID: 0000-0003-0881-1003
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About
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Research Areas
  • Genetic factors in colorectal cancer
  • Glutathione Transferases and Polymorphisms
  • Gastric Cancer Management and Outcomes
  • Cancer Genomics and Diagnostics
  • Bone Tumor Diagnosis and Treatments
  • Hernia repair and management
  • Pelvic and Acetabular Injuries
  • Aortic aneurysm repair treatments
  • Salivary Gland Tumors Diagnosis and Treatment
  • Brain Metastases and Treatment
  • COVID-19 and healthcare impacts
  • Toxin Mechanisms and Immunotoxins
  • Anorectal Disease Treatments and Outcomes
  • Abdominal Trauma and Injuries
  • Gastrointestinal Tumor Research and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Global Cancer Incidence and Screening
  • Dermatological diseases and infestations
  • Thyroid Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Body Image and Dysmorphia Studies
  • Cancer-related Molecular Pathways
  • Economic and Financial Impacts of Cancer
  • Nutrition and Health in Aging
  • Eicosanoids and Hypertension Pharmacology

Mersin Üniversitesi
2021-2025

Massachusetts Eye Research and Surgery Institute
2024

Uni Research (Norway)
2024

Ege University
2024

Abstract Aim This study aimed to compare laser application with sinus curettage against only in the treatment of pilonidal disease (PSD) terms postoperative complications, wound healing, and recurrence. Additionally, we investigate factors associated healing recurrence after PSD surgery. Patients methods included patients diagnosed between February 2019, September 2022. The were randomly assigned either + (L/C; n = 40) group or curettage-only (C; group. following data collected: demographic...

10.1007/s10103-025-04409-8 article EN cc-by Lasers in Medical Science 2025-03-18

Background: Total extraperitoneal (TEP) hernia repair is a minimally invasive method for the treatment of inguinal hernia. In this study, one group with balloon dissection and mesh fixation was compared another that underwent telescopic without fixation. This study aims to compare both methods in terms effectiveness, complications, pain scores, clinical outcomes. Material methods: retrospective evaluation prospectively acquired data from patients single-center setting. Patients were divided...

10.1089/lap.2025.0044 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2025-04-16

CDNK2 p16 plays a pivotal role in G1/S transition by regulating the p53 pathway, which was regulated nuclear oncoprotein, mouse double minute 2 (MDM2). Overexpression of MDM2 gene has been shown number tumor types, its amplification is found to associate with accelerated development and failure treatment both hereditary sporadic cancers. Although genetic association studies have revealed relationship between certain polymorphisms genes that play important roles progression colorectal cancer...

10.1089/dna.2012.1933 article EN DNA and Cell Biology 2013-06-18

Metabolism of chemical carcinogens, including their activation and detoxification, plays a key role in carcinogenesis. Microsomal epoxide hydrolase (EPHX1) has an important the metabolism polycyclic aromatic hydrocarbons detoxification procarcinogens. The aim this study was to investigate association between colorectal cancer (CRC) development EPHX1 gene polymorphisms. We investigated polymorphisms exon 3 (T>C, Tyr113His) 4 (A>G, His139Arg) 68 CRC patients 116 controls by polymerase chain...

10.1089/gtmb.2011.0223 article EN Genetic Testing and Molecular Biomarkers 2012-02-21

10.1007/s12262-024-04030-z article EN Indian Journal of Surgery 2024-01-17

Objective: Peritoneal cytology is used to detect the peritoneal spread of gastric cancer and assess survival rate. The aim this study was compare risk factors, recurrence, patients with positive negative before after resection. Materials methods: Patients who underwent elective surgery were retrospectively analysed. covered a period between September 2018 2020. After applying exclusion criteria, 57 included in study. For purpose study, taken from same three intra-abdominal regions resection...

10.7759/cureus.65832 article EN Cureus 2024-07-31

Introduction The coronavirus disease 2019 (COVID-19) outbreak, first reported in Wuhan, China, December 2019, quickly hit the world just one month, causing a global public health emergency. We aimed to investigate whether COVID-19 pandemic caused delay hospital admissions of breast cancer patients and diagnosis cancer, thus increasing tumor size stage disease. Materials methods Included study were who underwent surgery between 01/03/2019 01/03/2020 (pre-COVID-19, period) 01/03/2021...

10.7759/cureus.66501 article EN Cureus 2024-08-09

Amaç: Safra kesesi perforasyonu akut kolesistitin(AK) morbidite ve mortalite oranlarını artıran en ciddi komplikasyonudur. Akut perfore kolesistit (APK) yönetiminde net bir algoritma olmamakla birlikte erken dönemde operasyona uygun olmayan hastalar konservatif takip edilebilmektedir.Çalışmamızda APK nedeniyle edilen hastaların sonuçlarını değerlendirerek klinik deneyimimizi sunmayı amaçladık. Gereç yöntem Çalışmaya Aralık 2018- 2023 yılları arasında AK kliniğimizde 532 hasta dahil edildi....

10.19161/etd.1524037 article TR Ege Tıp Dergisi 2024-12-09

Background and Aim: Since the survival time is still low in end-stage gastric cancers, additional treatment prognostic factors are being investigated. This study aimed to evaluate significance of preoperatively measured C-reactive protein (CRP)/ Albumin ratio adenocarcinomas effect on postoperative survival. Patients Methods: A total 258 patients underwent elective adenocarcinoma surgery were investigated retrospectively. Disease-free, overall evaluated according last CT, MRI PET/CT scans...

10.19161/etd.1522823 article EN Ege Tıp Dergisi 2024-12-09

This study aims to investigate incisional hernia incidence and risk factors after abdominal aortic aneurysm occlusive disease surgery via a midline laparotomy.A total of 110 patients (66 males, 44 females; mean age: 69.3±8.8 years; range, 36 88 years) who underwent open elective for aortoiliac diseases or between January 2005 December 2016 were retrospectively analyzed. Both patient groups compared in terms surgical procedures, sex, age, American Society o f A nesthesiologists s core ( 1-3),...

10.5606/tgkdc.dergisi.2021.22340 article EN Turkish Journal of Thoracic and Cardiovascular Surgery 2021-10-20

Aim: The aim of this study is to determine whether a novel prognostic score can be obtained by including low muscle mass in the international (IPS) system. Materials & Methods: Psoas areas were determined PET/CT scans patients taken for staging at time diagnosis and after two cycles ABVD. After evaluating effect on overall survival, receiver operating characteristic (ROC) analyzes performed it IPS systems. Results: Overall survival was significantly lower with mass. Adding scores increased...

10.2217/bmm-2021-0696 article EN Biomarkers in Medicine 2021-11-10

Introduction: The single-port laparoscopic splenectomy procedure is a brand new technique. Although it reported that perioperative complications are less with conventional laparoscopy and open procedure, the number of studies comparing outcomes all three techniques not high. This study compares these in non-traumatic splenic diseases. Materials Methods: Total 82 patients (aged 18-72 years ) who underwent due to reasons between June 2011 December 2016 Ege University General Surgery...

10.5455/umj.20210702102448 article EN The Ulutaş medical journal/The ulutas medical journal 2021-01-01
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