A5006140664- Tendon Structure and Treatment
- Shoulder Injury and Treatment
- Tribology and Lubrication Engineering
- Innovative Microfluidic and Catalytic Techniques Innovation
- Hydrogels: synthesis, properties, applications
- Sports injuries and prevention
- Plant and fungal interactions
- 3D Printing in Biomedical Research
- Bee Products Chemical Analysis
Virginia Tech
2019-2021
University of California, Davis
2016
University of California System
2016
Lentivectors are widely used for gene delivery and have been increasingly tested in clinical trials. However, achieving safe, localized, sufficient expression remain key challenges effective lentivectoral therapy. Localized efficient can be promoted by developing material systems to deliver lentivectors. Here, we address the utility of microgel encapsulation as a strategy controlled release Three distinct routes ionotropic gelation alginate were incorporated into microfluidic templating...
ABSTRACT The deposition of aggrecan/hyaluronan (HA)‐rich matrix within the tendon body and surrounding peritenon impede healing result in compromised biomechanical properties. Hence, development novel strategies to achieve targeted removal aggrecan‐HA pericellular may be effective treating tendinopathy. current study examined therapeutic potential a recombinant human hyaluronidase, rHuPH20 (FDA approved for reducing HA accumulation tumors) murine Achilles 12‐week‐old C57Bl/6 male mice were...
Achilles tendinopathy is a debilitating condition affecting the entire spectrum of society and that increases risk tendon rupture. Effective therapies remain elusive, as anti-inflammatory drugs surgical interventions show poor long-term outcomes. Eccentric loading muscle-tendon unit an effective physical therapy for treatment symptomatic human tendinopathy. Here, we introduce novel mouse model hindlimb muscle designed to achieve tissue-targeted therapeutic exercise. This includes application...