Marwan Alhalabi

ORCID: 0000-0003-0914-6367
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About
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Research Areas
  • Ovarian function and disorders
  • Reproductive Biology and Fertility
  • Assisted Reproductive Technology and Twin Pregnancy
  • Sperm and Testicular Function
  • Endometriosis Research and Treatment
  • Sexual Differentiation and Disorders
  • Reproductive System and Pregnancy
  • COVID-19 and healthcare impacts
  • COVID-19 and Mental Health
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Gynecological conditions and treatments
  • Blood Coagulation and Thrombosis Mechanisms
  • Pregnancy and preeclampsia studies
  • Vitamin D Research Studies
  • Hormonal and reproductive studies
  • Growth Hormone and Insulin-like Growth Factors
  • Testicular diseases and treatments
  • Menstrual Health and Disorders
  • Uterine Myomas and Treatments
  • Sexual function and dysfunction studies
  • Systemic Lupus Erythematosus Research
  • Child Nutrition and Water Access
  • COVID-19 Clinical Research Studies
  • Ectopic Pregnancy Diagnosis and Management
  • Thyroid Disorders and Treatments

Damascus University
2016-2025

Taif University
2025

Al al-Bayt University
2023

Damascus Hospital
2012-2022

Qasyoun Private University
2021

Syrian Private University
2019

In subfertile women with poor ovarian reserve undergoing IVF does a mild stimulation strategy lead to comparable ongoing pregnancy rates in comparison conventional strategy?A leads similar as strategy.Women diagnosed are treated consisting of high-dose gonadotropins and pituitary downregulation long mid-luteal start GnRH-agonist protocol. Previous studies comparing low-dose GnRH-antagonist have been under powered their effectiveness is inconclusive.This open label multicenter randomized...

10.1093/humrep/dew282 article EN Human Reproduction 2016-11-05

Abstract Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age worldwide, and its related features like obesity, mental health issues hyperandrogenism may contribute to inadequately investigated problems such as sexual dysfunction (SD) lower urinary tract symptoms (LUTS). Therefore, this study examined impact PCOS on function (SF) Syrian by recruiting a total 178 age, whom 88 were diagnosed with according Rotterdam criteria 90 without...

10.1038/s41598-025-85544-8 article EN cc-by Scientific Reports 2025-01-06

Artificial Intelligence (AI), especially ChatGPT, is rapidly assimilating into healthcare, providing significant advantages in pharmacy practice, such as improved clinical decision-making, patient counselling, and drug information management. The adoption of AI tools heavily contingent upon practitioners' knowledge, attitudes, practices (KAP). This study sought to evaluate the knowledge pharmacists Saudi Arabia concerning utilization ChatGPT their daily activities. A cross-sectional was...

10.2147/iprp.s500689 article EN cc-by-nc Integrated Pharmacy Research and Practice 2025-03-01

Chromosomal rearrangements play a significant role in 50% of recurrent miscarriage cases. The incidence chromosomal abnormalities the population ranges from 1/625 to 1/1500. 2 most common types these are reciprocal and Robertsonian (Rob) translocation. Rob translocation can be found 1 1000 individuals is predominant type humans. This case highlights importance identifying such rare genetic patients with miscarriage. We report 27-year-old Syrian woman who presented at Orient Hospital...

10.1097/md.0000000000042128 article EN PubMed 2025-04-18

Problem: Syrian medical research synthesis lags behind that of neighboring countries. The war has exacerbated the situation, creating obstacles such as destroyed infrastructure, inflated clinical workload, and deteriorated training. Poor scientific writing skills have ranked first among perceived could be modified to improve conduct at every academic level. However, limited access personal physical resources in conflict areas consistently hampers implementation standard professional-led...

10.1080/10401334.2024.2332890 article EN Teaching and Learning in Medicine 2024-03-29

This study aims to investigate the effect of combining calcium and vitamin D supplements with metformin on menstrual cycle abnormalities, gonadotropins, IGF-1 system in D-deficient/insufficient PCOS women. is a randomized, placebo-controlled clinical trial. was performed Damascus University Obstetrics Gynecology Hospital Orient Hospital, Damascus, Syria. Forty women 25-OH-vitamin < 30 ng/ml were randomly assigned take either (1500 mg/daily) plus placebo or (1000 D3 (6000 IU/daily) orally for...

10.1155/2019/9680390 article EN cc-by Advances in Pharmacological Sciences 2019-07-01

Abstract Objective: The aim of this study was to evaluate the serum and follicular fluid levels Vascular Endothelial Growth Factor (VEGF) as possible predictive markers for IVF outcome in PCOS patients. Design: Prospective cross-sectional study. Materials Methods: Forty patients with 40 age weight matched control women were included All them enrolled program. Blood (FF) samples collected from all subjects on day oocyte retrieval. VEGF measured using enzyme linked immunosorbent assay (ELISA)....

10.1016/j.mefs.2015.11.001 article EN cc-by-nc-nd Middle East Fertility Society Journal 2015-12-13

Introduction Thyroid autoimmune (TAI) disease with a prevalence varying between 5 and 15%, represents the most common endocrine disorder in women reproductive age. Not only is TAI five to 10 folds more than men but also diseases often undiagnosed because it may be present without overt thyroid dysfunction for several years. Studies found an increased of referred fertility clinics compared normal population. In this analysis we aimed study among seeking care Damascus, Syria order understand...

10.7759/cureus.5315 article EN Cureus 2019-08-03

During the past three decades, growth charts have become one of principal tools for monitoring anthropometric development in individuals and populations as well. Growth references by CDC other countries been widely used our hospitals healthcare units clinical assessment children's development. The apparent overestimation underestimation many anthropometrics indicated need to construct own references. objective this study is establish national Syrian population 2-20-year-old.

10.1186/s12887-022-03331-0 article EN cc-by BMC Pediatrics 2022-05-14

COVID-19 ignited a global pandemic that, in Syria, further strained nation and its healthcare system already ravaged by years of war sanctions. The first case Syria was reported on March 22, 2020, this is the study that aimed to describe clinical characteristics, comorbidities, prognosis patients Syria.Demographic data for cross-sectional prospective were collected with positive polymerase chain reaction tests who admitted Al Assad Mouwasat university hospitals between April 1 January 31...

10.1016/j.amsu.2022.103816 article EN Annals of Medicine and Surgery 2022-05-21

Introduction: Inhibin-B is glycoproteins of the transforming growth factor-β superfamily, produced almost exclusively by Sertoli cells and has been proposed as direct markers their function indirect spermatogenesis. Our objective was to evaluate predictive value serum levels an indicator presence testicular spermatozoa in non-obstructive azoospermia (NOA), compared with other such FSH volume. Material methods: A total 228 patients idiopathic (NOA) were recruited this prospective study....

10.1016/j.mefs.2016.05.001 article EN cc-by-nc-nd Middle East Fertility Society Journal 2016-06-26

Infertility is inadequately acknowledged as a problem in developing countries. Thyroid Autoimmunity (TAI) has been neatly investigated for its association with unfavorable pregnancy and reproductive consequences. We aim to evaluate Clinical Pregnancy Rate (CPR) primary outcome following In Vitro Fertilization/Intra Cytoplasmic Sperm Injection (IVF/ICSI) women (TAI).A Retrospective cohort study included 584 who underwent IVF/ICSI treatment between November 2012 April 2017 Orient Hospital,...

10.1016/j.amsu.2021.102473 article EN Annals of Medicine and Surgery 2021-06-09

Two unrelated men complaining of primary male infertility presented to Orient Hospital in Damascus city. Physical examination showed moderate hypoandrogenic features. Both were azoospermic. Hormone profiles revealed an elevation follicle-stimulating hormone one patient, but all the other hormones tested within normal limits for both patients. Further genetic analyses, including karyotype and microdeletions AZF region Y chromosome, Mild androgen insensitivity syndrome was expected two...

10.1136/bcr-2017-220361 article EN BMJ Case Reports 2017-06-28

AMH, is a member of the transforming growth factor (TGF-β) produced by granulosa cells with highest expression being in small antral follicles. Our objective to evaluate predictive value follicular AMH levels as an indicator IVF outcomes PCOS patients. A total 63 patients undergoing trail were recruited for this prospective case-control study. The classified into three groups: Group I: 43 Polycystic ovary syndrome (PCOS). II: 20 normo-ovulatory because male infertility (control group). III:...

10.1016/j.mefs.2012.12.005 article EN cc-by-nc-nd Middle East Fertility Society Journal 2013-02-05

Our objective was to investigate the existence of an optimal period for oocyte retrieval in regards clinical pregnancy occurrence after administration recombinant human chorionic gonadotropin (rhCG) (Ovitrelle®).We studied digital records 3362 middle eastern couples who underwent vitro fertilization (IVF) treatment between 2019 and 2021.Through statistical testing, we found that there is a significant positive correlation up 37th hour, where at hour provide most outcome, especially case...

10.1186/s12884-022-04412-9 article EN cc-by BMC Pregnancy and Childbirth 2022-03-07

Insulin like growth factor-1 (IGF-1) has been found to stimulate follicular development, estrogen and progesterone production oocyte maturation. This study aims detect the changes in fluid IGF-1 levels normo-ovulatory women undergoing vitro fertilization (IVF) cycle evaluate possibility of be a predictive marker for IVF outcome women. prospective cross-sectional was performed among 88 who were categorized according pregnancy (clinical pregnancy) into two groups: 55 pregnant 33 non-pregnant...

10.1016/j.mefs.2017.01.002 article EN cc-by-nc-nd Middle East Fertility Society Journal 2017-02-24

Obstetric morbidities represent a common hallmark manifestation of antiphospholipid syndrome (APS), with the recurrent loss pregnancy as main complication. The presence antibodies (APA) and its potential impact have not been established yet in infertile women seeking assisted reproduction technologies Syria.This study aims to determine prevalence anticardiolipin (aCL) lupus anticoagulation (LAC) their association age In vitro fertilization (IVF) outcomes large sample Syrian women.The...

10.1016/j.amsu.2021.102301 article EN Annals of Medicine and Surgery 2021-04-19

Gonadotropin-releasing hormone (GnRH) analogues are used to prevent premature luteinizing (LH) surge during In-Vitro Fertilization. However, the follicular fluid levels of Placental growth factor (FF PlGF), novel angiogenic factor, differ significantly between GnRH-agonist and GnRH-antagonist protocols. Thus, we compared IVF/ICSI outcomes their correlations with FF PlGF in polycystic ovary syndrome (PCOS) normo-ovulatory women different hyperstimulation

10.1016/j.amsu.2022.104096 article EN Annals of Medicine and Surgery 2022-06-25

<title>Abstract</title> <bold>Background:</bold> Infertility is an important health problem, affecting couples worldwide. Non -obstructive azoospermia the most severe form of azoospermia, which almost idiopathic or caused by different causes such as chemotherapy and genetic disorders. Testicular Fine needle aspiration (or sperm (TESA)) a simple, cost-effective less invasive than testicular extraction. <bold>Materials Methods:</bold> 320 Middle Eastern patients with NOA were recruited in this...

10.21203/rs.3.rs-3713322/v1 preprint EN cc-by Research Square (Research Square) 2024-01-05
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