A5045226612- Metal complexes synthesis and properties
- Protein Interaction Studies and Fluorescence Analysis
- X-ray Diffraction in Crystallography
- Free Radicals and Antioxidants
- Crystallization and Solubility Studies
- Advanced Chemical Physics Studies
- Ferrocene Chemistry and Applications
- Crystallography and molecular interactions
- DNA and Nucleic Acid Chemistry
- Click Chemistry and Applications
- Organometallic Compounds Synthesis and Characterization
- Laser-induced spectroscopy and plasma
- Chemical Thermodynamics and Molecular Structure
- Photochemistry and Electron Transfer Studies
- Various Chemistry Research Topics
- Biotin and Related Studies
- Synthesis of Tetrazole Derivatives
- Nanomaterials for catalytic reactions
- Fullerene Chemistry and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Photosynthetic Processes and Mechanisms
- Advanced oxidation water treatment
- Vitamin C and Antioxidants Research
- Chemical Synthesis and Analysis
- Organometallic Complex Synthesis and Catalysis
Ardakan University
2016-2022
Isfahan University of Technology
2011-2019
Ardahan University
2016
A rare mononuclear Cu(II) complex, trans-[Cu(cip)2(OH)2]·2CH3OH·6H2O, where cip+/− is a zwitterionic form (+H2N–⋯–COO−) of ciprofloxacin, has been synthesized and characterized by spectroscopic methods X-ray crystallography. In vitro studies (UV-Vis spectroscopy, emission titration, voltammetric techniques, gel electrophoresis) show that the complex interacts with calf-thymus DNA (CT-DNA) via an intercalative binding mode. The microenvironment secondary structure BSA are changed in presence...
The interaction of a new cyclometallated Rh(<sc>iii</sc>) complex with DNA and BSA was investigated. three-layer ONIOM method employed to calculate the energy between complex.
The electronic structures and photoelectron spectra of several fat-soluble vitamins including A (all-<italic>trans</italic>-retinol its two derivatives, 13-<italic>cis</italic>-retinoic acid all-<italic>trans</italic>-retinoic acid), D<sub>2</sub>, D<sub>3</sub>, E (consisting α-tocopherol, β-tocopherol, γ-tocopherol δ-tocopherol) K were studied theoretically in this work.
A new oxidovanadium(IV) complex VO(L)(Jug) (HL = 5-methoxy-1,3-bis (1-methyl-1H-benzo[d]imidazol-2-yl)benzene, Jug juglone) was synthesized and characterized. Interactions of the V(IV) with calf thymus DNA (CT DNA) human serum albumin were studied using different techniques such as UV–vis fluorescence emission spectroscopy. The experimental results confirmed by molecular docking study. can efficiently cleave pUC19 in presence Hydrogen peroxide. Also, vitro cytotoxicity properties evaluated...
A Cu(II) complex, that is, [Cu(CNC-B3)(IM-B7)](PF6)2, 1, containing CNC-B3 (L2) = CNC–pincer–vitamin B3 and IM-B7 (L3) 1H-imidazole-1-methanamine-vitamin B7 conjugates, was developed as a potential chemotherapeutic agent for breast cancer cell lines. The complex brings about remarkable in vitro cytotoxicity comparison with cisplatin tamoxifen against MDA-MB-231 MCF-7 Interestingly, the considerably less toxic to MRC-5 normal cells. DNA/human serum albumin-binding capacity of confirmed by...
A part of signal transducer smoothened (SMO) protein including antitumor agent LY2940680. The site this was considered for the docking 716 ligands.
In this work, the study was performed with 37 gas-phase conformers of biotin and two biologically active in ligand-receptor complexes astavidin streptavidin. The ionization energies photoelectron spectra were calculated by methods: general-R symmetry-adapted cluster-configuration interaction (general-R-SAC-CI) method outer-valence Green's function (OVGF) method. spectrum each conformer using basis set D95 (df,pd) for both methods. simulated free molecules bioactive methods compared. Natural...
The new heteronuclear molybdocene-gold complex 1, [(η5-Cp)2MoII[(μ2-η2-dtc)2Nap]AuIII(LC)](PF6), (η5-Cp: η5-cyclopentadienyl, (dtc)2Nap: 2,7-bis(dithiocarbamate)naphthalene, LC: lidocaine) was synthesized and evaluated for biological activity. With the aim of assessing possible DNA-binding mode, interaction 1 with calf thymus DNA (CT DNA) investigated by UV spectroscopy, emission titration, viscosity measurement. Also, binding to human serum albumin (HSA) considered UV-Vis fluorescence...
Abstract A novel cyclometalated gold(iii) complex supported by chlorambucil coupled with phenylpyridine (CHL-N^C) and a hybrid of vitamin B1 dithiocarbamate (B1-DTC) the formula [(CHL-N^C)AuIII(B1-DTC)](Cl2), 1, was synthesized fully characterized using different techniques, including multinuclear NMR, mass spectrometry, elemental analysis. This is water-soluble stable in biological environment. new offers scaffold to explore properties complexes as an anticancer drug. The antiproliferative...
Green application of a high-nitrogen, zeolite-like, porous metal–organic framework, IFMC-1 (Institute Functional Material Chemistry), is reported for dye pollutant removal and wastewater treatment. The contained high-nitrogen-content ligand without an NH2 group (H3dttz), dimethylacetamide, Zn ion. synthesis H3dttz from diaminomaleonitrile was initiated after closure the triazole ring formation 4,5-dicyano-2H-1,2,3-triazole as intermediate material; thus, two tetrazole rings were obtained in...