A5086743856- Cytokine Signaling Pathways and Interactions
- Cancer Cells and Metastasis
- Prostate Cancer Treatment and Research
- TGF-β signaling in diseases
- Estrogen and related hormone effects
- Toxic Organic Pollutants Impact
- Coronary Interventions and Diagnostics
- Atherosclerosis and Cardiovascular Diseases
- Cosmology and Gravitation Theories
- Cardiac Imaging and Diagnostics
- Nuclear Receptors and Signaling
- Vitamin D Research Studies
- MicroRNA in disease regulation
- Medicinal Plant Pharmacodynamics Research
- Cancer, Stress, Anesthesia, and Immune Response
- Receptor Mechanisms and Signaling
- Cancer, Lipids, and Metabolism
- Cancer-related molecular mechanisms research
- DNA Repair Mechanisms
- Space Science and Extraterrestrial Life
- Cell Adhesion Molecules Research
- PI3K/AKT/mTOR signaling in cancer
- Protease and Inhibitor Mechanisms
- Cardiovascular Disease and Adiposity
- Spaceflight effects on biology
University of Münster
2016
Max Planck Institute for Molecular Biomedicine
2015
Czech Academy of Sciences, Institute of Biophysics
2009-2012
Abstract BACKGROUND Epithelial–mesenchymal transition (EMT) underlying cancer cell invasion and metastasis has been thoroughly studied in prostate cancer. Although EMT markers have clinically observed benign hyperplasia, molecular events the onset progression of cells not described. METHODS BPH‐1 was induced by TGF‐β1 treatment kinetics expression markers, regulators, selected miRNAs assessed western blotting quantitative RT‐PCR. RESULTS accompanied rapid up‐regulation SNAI2/Slug ZEB1...
The hyperlipidemic mouse model HypoE/SRBI<sup>−/−</sup> has been shown to develop occlusive coronary atherosclerosis followed by myocardial infarctions and premature deaths in response high-fat, high-cholesterol diet (HFC). However, the causal connection between atherosclerotic plaque rupture events arteries not investigated so far. objective of this study was assess whether diet-induced ruptures trigger atherothrombotic occlusions, resulting HFC-fed mice. <b>Methods:</b> mice were...
The plasticity of differentiated adult cells could have a great therapeutic potential, but at the same time, it is characteristic progression serious pathological states such as cancer and fibrosis. In this study, we report on application real-time noninvasive system for dynamic monitoring cellular plasticity. Analysis cell impedance profile recorded index using analyzer revealed its significant increase after treatment prostate epithelial with transforming growth factor-β1. Changes in were...