A5074579779- Genetic Mapping and Diversity in Plants and Animals
- Chromosomal and Genetic Variations
- Animal Genetics and Reproduction
- Genetic diversity and population structure
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- RNA Research and Splicing
- Evolution and Genetic Dynamics
- Molecular Biology Techniques and Applications
- DNA and Nucleic Acid Chemistry
- Genomics and Chromatin Dynamics
- Animal Ecology and Behavior Studies
- DNA Repair Mechanisms
- Sperm and Testicular Function
Institute of Cytology and Genetics
2018-2023
Novosibirsk State University
2018-2023
Siberian Branch of the Russian Academy of Sciences
2021
Federal Scientific Center for Animal Husbandry named after Academician L.K. Ernst
2019
Introduction: Meiotic recombination is one of the major sources genetic diversity. Understanding cytogenetic basis for rate alterations essential to explain patterns variation observed between different groups species. Common degu (Octodon degus) a South American rodent speciose and highly chromosomal variable Ctenohystrica clade, on which relatively few studies have been carried out. It has mostly bi-armed karyotype, making it an interesting model research. Methods: Using immunolocalization...
Hybrid sterility is an important step in the speciation process. Hybrids between dwarf hamsters Phodopus sungorus and P. campbelli provide a good model for studies cytological genetic mechanisms of hybrid sterility. Previous hybrids detected multiple abnormalities spermatogenesis high frequency dissociation X Y chromosomes at meiotic prophase. In this study, we found that autosomes males females underwent paring recombination as normally their parental forms did. The male showed...
Closely related mammalian species often have differences in chromosome number and morphology, but there is still a debate about how these relate to reproductive isolation. To study the role of rearrangements speciation, we used gray voles Alexandromys genus as model. These high level polymorphism substantial karyotypic divergence. We investigated testis histology meiotic behavior captive-bred colonies maximowiczii, mujanensis, two races evoronensis, their interracial interspecies hybrids,...
The formation of hybrid sterility is an important stage speciation. voles the genus Microtus , which most speciose rodents, provide a good model for studying cytological mechanisms sterility. “ mystacinus ” group subgenus (2 n = 54) comprising several recently diverged forms with unclear taxonomic status are especially interesting. To resolve and kermanensis we crossed both rossiaemeridionalis M. alone arvalis “obscurus” transcaspicus examined reproductive performance their F1 hybrids. All...
Amplified sequences constitute a large part of mammalian genomes. A chromosome 1 containing 2 (up to 50 Mb) homogeneously staining regions (HSRs) separated by small inverted euchromatic region is present in many natural populations the house mouse (<i>Mus musculus musculus</i>). The HSRs are composed long-range repeat cluster, <i>Sp100-rs</i>, with length 100 kb. In order understand organization and function meiotic chromosomes, we examined synapsis recombination male...
Benefits and costs of meiotic recombination are a matter discussion. Because breaks allele combinations already tested by natural selection generates new ones unpredictable fitness, high rate is generally beneficial for the populations living in fluctuating or rapidly changing environment costly stable environment. Besides genetic benefits costs, there cytological effects recombination, both positive negative. Recombination necessary chromosome synapsis segregation. However, it involves...
Hybridization of domestic animal breeds with their wild relatives is a promising method for increasing the genetic diversity farm animals. Resource populations derived from hybridization various sheep mouflon and argali are an important source breeding material. The karyotypes differ Robertsonian translocation, which occurred in common ancestor (Ovis aries) due to centric fusion chromosomes 5 11 (O. ammon) into chromosome 3 sheep. It known that heterozygosity translocation can lead synapsis,...