A5036321995- Innovative Microfluidic and Catalytic Techniques Innovation
- Biosensors and Analytical Detection
- Electrowetting and Microfluidic Technologies
- Genetics, Aging, and Longevity in Model Organisms
- Cell Image Analysis Techniques
- CRISPR and Genetic Engineering
- Parasitic Diseases Research and Treatment
- Microfluidic and Capillary Electrophoresis Applications
- Animal Behavior and Welfare Studies
- Advanced Sensor and Energy Harvesting Materials
- Cutaneous Melanoma Detection and Management
- Spaceflight effects on biology
- Food Supply Chain Traceability
- AI in cancer detection
- Quantum Dots Synthesis And Properties
- Parasite Biology and Host Interactions
- Fluid Dynamics and Heat Transfer
- Optical Coherence Tomography Applications
- Parasites and Host Interactions
- Electrohydrodynamics and Fluid Dynamics
- Interactive and Immersive Displays
- Modular Robots and Swarm Intelligence
- Electromagnetic Fields and Biological Effects
Iowa State University
2015-2021
Defense Acquisition Program Administration
2021
Precision swine production can benefit from autonomous, noninvasive, and affordable devices that conduct frequent checks on the well-being status of pigs. Here, we present a remote monitoring tool for objective measurement some behavioral indicators may help in assessing health welfare status-namely, posture, gait, vocalization, external temperature. The multiparameter electronic sensor board is characterized by laboratory measurements animal tests. Relevant are discussed implementing...
In paper microfluidics, the development of smart and versatile switches is critical for regulation fluid flow across multiple channels.
Among the different types of skin cancer, melanoma is considered to be deadliest and difficult treat at advanced stages. Detection earlier stages can lead reduced mortality rates. Desktop-based computer-aided systems have been developed assist dermatologists with early diagnosis. However, there significant interest in developing portable, at-home diagnostic which assess risk cancerous lesions. Here, we present a smartphone application that combines image capture capabilities preprocessing...
Infections from parasitic nematodes (or roundworms) contribute to a significant disease burden and productivity losses for humans livestock. The limited number of anthelmintics antinematode drugs) available today treat these infections are rapidly losing their efficacy as multidrug resistance in parasites becomes global health challenge. We propose an engineering approach discover anthelmintic drug combination that is more potent at killing wild-type Caenorhabditis elegans worms than four...
An open microfluidic system is presented to manipulate discrete droplets on plastic sheets by using controlled, mechanical agitations.
The ability to study bacteria at the single cell level has advanced our insights into microbial physiology and genetics in ways not attainable by studying large populations using more traditional culturing methods. To improve methods characterize cellular level, we developed a new microfluidic platform that enables cells be exposed metabolites gradient of concentrations. By designing low-cost, three-dimensional devices with adhesive tapes tailoring them for bacterial imaging, avoided...
In nature, several organisms possess a magnetic compass to navigate or migrate them desired locations. It is thought that these may use biogenic matter light-sensitive photoreceptors sense and orient themselves in fields. To unravel the underlying principles of magnetosensitivity magnetoreception, previous experiments have been conducted on bacteria, vertebrates, crustaceans, insects. this study, model organism, C. elegans, used test their response sensitivity static fields range 5 milli...
New combinations of existing antibiotics are being investigated to combat bacterial resilience. This requires detection technologies with reasonable cost, accuracy, resolution, and throughput. Here, we present a multi -drug screening platform for cultures by combining droplet microfluidics, search algorithms, imaging wide field view. We remotely alter the chemical microenvironment around cells test 12 resistant cell types chemicals. Fluorescence intensity readouts allow us infer resistance...
Today, the area of point-of-care diagnostics is synonymous with paper microfluidics where cheap, disposable, and on-the-spot detection toolkits are being developed for a variety chemical tests. In this work, we present novel application microfluidic paper-based analytical devices (microPADs) to study behavior small model nematode, Caenorhabditis elegans. We describe schemes microPAD fabrication on plastic substrates membranes created in agarose Pluronic gel. Methods demonstrated loading,...