A5008298503- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Dementia and Cognitive Impairment Research
- Pharmaceutical studies and practices
- Frailty in Older Adults
- Chronic Disease Management Strategies
- Schizophrenia research and treatment
- Geriatric Care and Nursing Homes
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmacy and Medical Practices
- Patient Safety and Medication Errors
- Intensive Care Unit Cognitive Disorders
- Emergency and Acute Care Studies
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical Economics and Policy
- Mental Health Treatment and Access
- Patient Satisfaction in Healthcare
- Safe Handling of Antineoplastic Drugs
- Innovations in Medical Education
- Balance, Gait, and Falls Prevention
- Nonlinear Differential Equations Analysis
- advanced mathematical theories
- Palliative Care and End-of-Life Issues
The University of Sydney
2016-2025
Northern Sydney Local Health District
2015-2025
Royal North Shore Hospital
2015-2024
The University of Queensland
2024
National Health and Medical Research Council
2016-2020
UNSW Sydney
2017
Keogh Institute for Medical Research
2016
The potential harms of some medications may outweigh their benefits (inappropriate medication use). Despite recommendations to avoid the use potentially inappropriate (PIMs) in older adults, prevalence PIM is high different settings including residential aged care. However, it remains unclear what costs these are this setting. main objective study was determine PIMs adults living A secondary examine if there a difference home-like model care compared an Australian standard Participants...
Background: Anticholinergic and sedative (ACh-Sed) medications are commonly prescribed for older adults associated with adverse events. Objectives: (1) To investigate perspectives of health care practitioners (HCPs) surrounding deprescribing (withdrawal) ACh-Sed in adults; (2) to assess HCPs’ on the design implementation a report patient’s exposure using Drug Burden Index (DBI) pharmacological tool. Methods: This was qualitative study focus groups purposive samples accredited pharmacists...
Objective Medication-related burden (MRB) is a negative experience with medicine, which may impact on psychological, social, physical and financial well-being of an individual. This study describes the development initial validation instrument specifically designed to measure MRB functioning well-being—the Medication-Related Burden Quality Life (MRB-QoL) tool. Methods An pool 76-items for MRB-QoL was generated. The link survey sent sample consumers living at least one chronic medical...
Abstract Anticholinergic medications are frequently used in older adults to manage a wide range of chronic diseases. burden associated with the use multiple anticholinergic effects is cumulative within an individual, and particularly susceptible adverse these medications. These include dry mouth resulting poor oral health, constipation, urinary retention confusion. Use has been impaired cognitive physical function, increased risk falls, vascular events hospitalisation. Consideration...
Psychotropic medications have been associated with many adverse outcomes in older people living residential care. Home-like models of care may be preferable to traditional and we hypothesized that this model impact on the prevalence psychotropic medications. The objectives were to: 1) examine associations between quality life adults facilities a high cognitive impairment dementia 2) determine if there was difference which provide small group home-like compared 'standard model'...
Abstract Cumulative exposure to anticholinergic and sedative medications has been associated with worsening physical function in older adults. We evaluated the feasibility of measuring using wearable devices explored impact reducing medication burden a pilot study community-dwelling adults aged 60 years older. Evaluations included 10-meter walk test (10MWT), Short Physical Performance Battery (SPPB), mini-BESTest. Two participants/month were recruited one clinic 2022. The five participants...
Objectives (i) To develop a version of the revised Patients’ Attitude Towards Deprescribing ( rPATD ) questionnaire for people with mild cognitive impairment (MCI) and mild‐to‐moderate dementia cog); (ii) to capture beliefs attitudes this population their carers about deprescribing through pilot study. Methods First, cog was modified from tested in small group participants MCI or dementia, then, we conducted study carers’ . Results Twenty‐one 11 carer (forming dyads) participated Eighty‐one...
The Goal-directed Medication Review Electronic Decision Support System (G-MEDSS) assesses and reports a patient's goals, attitudes to deprescribing Drug Burden Index (DBI) score, measure of cumulative exposure anticholinergic sedative medications. This study evaluated the effect implementing G-MEDSS in home medicines reviews (HMRs) on DBI clinical outcomes.A cluster-randomised trial was performed across Australia. Accredited pharmacists were randomised into intervention (G-MEDSS with usual...
Abstract Background Pharmacists involvement in residential aged care facilities has traditionally been limited to that of an external contractor providing medication reviews, or supply. Aim To explore Australian pharmacists’ interest and perceived preparedness work as on-site pharmacists care. Method National cross-sectional anonymous online survey open for two weeks (September 17th October 1st 2022) consisting Likert-type, multiple choice selection questions. were recruited using a broad...
Implementation of the Drug Burden Index (DBI) as a risk assessment tool in clinical practice may facilitate deprescribing. The purpose this study is to evaluate how comprehensive intervention bundle using DBI impacts (i) proportion older inpatients with at least one DBI-contributing medication stopped or dose reduced on discharge, compared admission; and (ii) changes deprescribing different classes during hospitalisation. This before-and-after was conducted an Australian metropolitan...
Our aim in this research was to establish whether integrating an electronically generated calculation and report on the Drug Burden Index (DBI) Home Medicines Review (HMR) setting is accurate, feasible useful risk assessment tool assess of anticholinergic sedative medications; intervention DBI together with HMR associated a reduced use medications older community-dwelling adults Australia.An interventional feasibility study conducted. Accredited clinical pharmacists (APs) were recruited...