A5062095639- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Transplantation: Methods and Outcomes
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Cardiac pacing and defibrillation studies
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Coronary Artery Anomalies
- Acute Kidney Injury Research
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Cardiovascular Health and Risk Factors
- Central Venous Catheters and Hemodialysis
- Innovations in Medical Education
- Mitochondrial Function and Pathology
- Advanced battery technologies research
- Pericarditis and Cardiac Tamponade
- Health Policy Implementation Science
- Membrane-based Ion Separation Techniques
- Machine Learning in Healthcare
Lucile Packard Children's Hospital
2016-2024
Stanford University
2015-2024
Michigan Medicine
2022
C. S. Mott Children's Hospital
2022
University of Michigan
2022
Palo Alto University
2015-2020
Stanford Medicine
2020
Pediatrics and Genetics
2016
Boston Children's Hospital
2005-2014
Harvard University
2005-2014
Ventricular assist device (VAD) support for children with single ventricle (SV) heart disease remains challenging. We performed a single-center retrospective review of SV patients on VAD and examined survival to transplant using the Kaplan–Meier method. Patients transplanted were compared those who died support. Between 2009 2017, there 14 1,112 patient-days Stages palliation included pre-Glenn ( n = 5), Glenn Fontan 4). Eight (57%) successfully bridged at median 107 days. Deaths occurred...
To determine whether mortality differs between roller and centrifugal pumps used during extracorporeal membrane oxygenation in infants weighing less than 10 kg.Retrospective propensity-matched cohort study.All centers reporting to the Extracorporeal Life Support Organization.All patients kg supported on 2011-2016 within Organization Registry.Centrifugal pump recipients were propensity matched (1:1) based predicted probability of receiving a using demographic variables, indication for...
Objectives: To report on survival from a large multicenter cohort of neonates with hypoplastic left heart syndrome requiring extracorporeal membrane oxygenation–assisted cardiopulmonary resuscitation after stage 1 palliation operation. Design: Retrospective analysis data the Extracorporeal Life Support Organization registry (1998 through 2013). We computed to hospital discharge for (age < 30 d) who required oxygenation and evaluated factors associated mortality using multivariate logistic...
Purpose: Congenitally corrected transposition of the great arteries (CC-TGA) is a complex form congenital heart defect with numerous anatomic subgroups. The majority patients CC-TGA are excellent candidates for double-switch procedure. However, in absence an unrestrictive ventricular septal or subpulmonary stenosis, left ventricle (LV) may undergo involution and require retraining prior to double switch. purpose this study was review our experience having who required LV Methods: This...
In our retrospective multicenter study of patients 0 to 18 years age who survived extracorporeal life support (ECLS) between January 2010 and December 2018, we sought characterize the functional status scale (FSS) ECLS survivors, determine change in FSS from admission discharge, examine risk factors associated with development new morbidity unfavorable outcome. During period, there were 1,325 runs, 746 (56%) hospital discharge. Pediatric accounted for 56%. Most common indication was...
Objectives: Increased pulmonary dead space fraction (VD/VT) has been associated with prolonged mechanical ventilation after surgery for congenital heart disease. The association of VD/VT clinical outcomes in neonates undergoing stage 1 palliation single ventricle disease not reported. We describe changes VD/VT, differences based on shunt type (right to artery conduit vs modified Blalock-Taussing shunt) and postoperative patients palliation. Design: Retrospective chart review demographic,...
OBJECTIVES: Patients undergoing cardiac surgery using cardiopulmonary bypass have variable degrees of blood oxygen tension during surgery. Hyperoxia has been associated with adverse outcomes in critical illness. Data are not available regarding the association hyperoxia and infants bypass. We hypothesize that among surgery, is greater odds morbidity mortality. DESIGN: Retrospective study. SETTING: Single center at an academic tertiary children’s hospital. PATIENTS: All (< 1 yr) between...
Clinical effectiveness (CE) programs promote standardization to reduce unnecessary variation and improve healthcare value. Best practices for successful sustainable CE remain in question. We developed implemented our inaugural clinical pathway with the aim of incorporating lessons learned build a program at academic children's hospital.
Mechanical circulatory support (MCS), including ventricular assist device (VAD) support, is a leading cause of stroke in children; however, existing pediatric recommendations do not apply to many VAD patients. We sought develop multidisciplinary pathway improve timely and effective acute care examine the early performance expediting care. Stakeholders from heart failure, cardiac intensive care, neurology, interventional radiology, neuroradiology, neurosurgery, pharmacy, adult convened at...
Abstract Objectives To evaluate the incidence, severity, and outcomes of pulmonary hemorrhage in children with Alagille syndrome (AGS) undergoing cardiac catheterization, to find variables associated this population. Background Children AGS have a high incidence bleeding complications during invasive procedures. It has been our impression that catheterization‐associated is more common AGS, but there are no published data on topic. Methods This was retrospective single institution study...