A5027691017- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Gastroesophageal reflux and treatments
- Congenital Heart Disease Studies
- Gastric Cancer Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Eosinophilic Esophagitis
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Dysphagia Assessment and Management
- Congenital Diaphragmatic Hernia Studies
- Aortic Disease and Treatment Approaches
- Tracheal and airway disorders
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Helicobacter pylori-related gastroenterology studies
- Organ and Tissue Transplantation Research
- Trauma Management and Diagnosis
- Cardiac, Anesthesia and Surgical Outcomes
- Blood transfusion and management
- Coronary Artery Anomalies
- Signaling Pathways in Disease
- Pathogenesis and Treatment of Hiccups
- Potassium and Related Disorders
- Erythrocyte Function and Pathophysiology
Seattle Children's Hospital
2023-2024
University of Washington
2023-2024
United States Food and Drug Administration
2023
Boston Children's Hospital
2020-2023
Harvard University
2023
Trinity College Dublin
2019-2021
St. James's Hospital
2019-2021
Stanford Health Care
2020
Stanford University
2016-2020
Lucile Packard Children's Hospital
2018-2019
The genetic mechanisms underlying aortic stenosis (AS) and insufficiency (AI) disease progression remain unclear. We hypothesized that normal valves those with AS or AI all exhibit unique transcriptional profiles. Normal control (NC) were collected from non-matched donor hearts otherwise acceptable for transplantation (n = 5). Valves 5, each) patients undergoing surgical valve replacement. High-throughput sequencing of total RNA revealed 6438 differentially expressed genes (DEGs) vs. NC,...
To evaluate the short- and long-term outcomes of cardiac repair versus nonoperative management in patients with trisomy 13 18 congenital heart disease.
Data on the long-term symptom burden in patients surviving oesophageal cancer surgery are scarce. The aim of this study was to identify most prevalent symptoms and their interactions with health-related quality life.This a cross-sectional cohort who underwent 20 European centres between 2010 2016. Patients had be disease-free for at least 1 year. They were asked complete 28-symptom questionnaire single time point, year after surgery. Principal component analysis used assess clustering...
A 40-year-old male was referred for consideration of anti-reflux surgery.He had a history severe cyclical hiccups since 2008 lasting 7-10 days per episode and taking omeprazole (40 mg daily) heartburn.His initial endoscopy performed while hiccupping showed LA grade B erosive esophagitis.Highresolution esophageal manometry (HRM) he hiccuping mechanically defective lower sphincter (LES) complete absence peristalsis (total LES length: 1.3 cm [nmL 2.7-4.8];mean resting pressure: 4.4 mmHg 13-43...
The Yasui operation was introduced in 1987 for patients with 2 adequate ventricles, a ventricular septal defect, and aortic atresia or interrupted arch. Despite promising early outcomes, left outflow tract obstruction (LVOTO) remains long-term concern. purpose of this study is to report our institutional experience the operation.We retrospectively reviewed all undergoing between 1989 2021. Results are reported as median interquartile range (IQR).Twenty-five underwent (19 primary), at 11 days...