A5101695611- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Restless Legs Syndrome Research
- Autism Spectrum Disorder Research
- Botulinum Toxin and Related Neurological Disorders
- Autoimmune Neurological Disorders and Treatments
- Advanced Topology and Set Theory
- Cardiovascular Function and Risk Factors
- Mathematics and Applications
- Advanced Differential Equations and Dynamical Systems
- Glycogen Storage Diseases and Myoclonus
- Sleep and Wakefulness Research
- Neurological and metabolic disorders
- Prion Diseases and Protein Misfolding
- Iterative Learning Control Systems
- Fuzzy Logic and Control Systems
- Neurobiology of Language and Bilingualism
- Voice and Speech Disorders
- Pleural and Pulmonary Diseases
- Advanced Algebra and Logic
- Ultrasound in Clinical Applications
- Neural Networks and Applications
- Cerebrospinal fluid and hydrocephalus
- Fetal and Pediatric Neurological Disorders
Illinois Institute of Technology
2025
The Alfred Hospital
2008-2019
Monash University
2012-2018
University of California, San Diego
2013
Baker Heart and Diabetes Institute
2012
University College London
2011
National Hospital for Neurology and Neurosurgery
2011
St Vincent's Hospital
2003
Aberystwyth University
1928
Abstract Sphincter electromyography (spEMG) is often used as an ancillary test when multiple system atrophy (MSA) suspected. Our aim was to determine the clinical features associated with spEMG being performed, influence of result on final diagnosis, and its utility a investigation. A retrospective audit all cases in Queen Square Brain Bank between 1989 2002 performed. The diagnostic accuracy were compared patients whom performed those it not. From 845 sets complete records, we identified 37...
The transcription factor ΔFosB is a mediator of maladaptive neuroplasticity in animal models Parkinson's disease (PD) and L-DOPA-induced dyskinesia. Using an antibody that recognizes all known isoforms FosB ΔFosB, we have examined the expre
A number of cognitive abnormalities have been identified as putative diagnostic markers in neurodegenerative parkinsonism based on statistically significant differences between diseases. The effect sizes these frequently not reported, making practical interpretation the results difficult. objective this study was to assess potential contribution testing diagnosis parkinsonian disorders by quantifying size previously differentiating features. Medline search 1038 articles. Nineteen studies...
Abstract Levodopa‐carbidopa intestinal gel (LCIG) is an effective treatment for Parkinson disease. Initiating therapy involves initial naso‐jejunal (NJ) titration phase. The NJ phase prolonged with significant morbidity. aim of this study to assess the impact proceeding without on resource utilisation and outcomes patients. Twenty‐five patients were started LCIG using existing levodopa equivalent dose (LED). We recorded change in LED, length hospital stay, readmission rates use outpatient...
Sleep benefit (SB) in Parkinson's disease refers to improved motor symptoms upon waking despite an entire night without medications. Although it was first proposed 30 years ago, this phenomenon proved difficult investigate, and its true prevalence underlying mechanisms remain unclear.This study aimed identify quantify SB through measurement of function using a validated smartphone application characteristics that predicted SB.Ninety-two patients recruited from 2 Movement Disorder Services...
To evaluate the proportion of Parkinson's disease (PD) patients identified as having advanced (APD) according to physician's judgement in Australia.This cross-sectional, non-interventional observational study was performed movement disorder clinics from 18 countries. Results Australia are presented. Participants included consecutive adults with PD attending routine clinical visits, or inpatients, who could speak English. The primary outcome diagnosed APD via physician judgement.100 were...
SUMMARY The neurofibrillary tau pathology of progressive supranuclear palsy (PSP) has been associated with a number different clinical syndromes that all ultimately lead to death and disability within 6–10 years. In 1964, Steele, Richardson Olszewski predicted the classic syndrome they had described was specific topographic distribution PSP–tau neurodegeneration other may occur if brain regions were affected. spectrum disease related is indeed broader than 40 years ago. addition form PSP...
Abstract The clinical and electrophysiological aspects of a case where brainstem reticular reflex myoclonus was related to an enlarging pontine lesion are described. It had the unusual characteristic being evoked by sustained up gaze left gaze. © 2003 Movement Disorder Society
The notion of absorbent ordered filters in implicative semigroups is introduced, and its fuzzification considered. Relations among (fuzzy) or- dered filters, positive are stated. extensionproperty for established. Conditions to be provided. notions normal/maximal fuzzy complete introduced their properties investigated.
<h3>Objectives</h3> To describe the clinical features and disease severity in a prospectively studied cohort with orthostatic tremor (OT). <h3>Methods</h3> Patients fulfilling diagnostic criteria for OT completed questionnaire regarding characteristics, medication response, fall frequency use of gait aids. isolation were classified Primary OT, while those additional neurological signs OT-plus. Interviews identified domains inclusion new Impact Profile (OTIP). Forty-seven items across...
Objective: To describe the clinical features of orthostatic tremor (OT) in a first ever prospectively studied cohort and to develop disease specific questionnaire quantifying impact on patients’ function quality life. Background: OT is rare condition characterized by unsteadiness standing with an associated 13–18Hz leg tremor, few therapeutic options. There are no established, objective markers severity. Design/Methods: Patients fulfilling diagnostic criteria for completed regarding...