A5061348488- Cystic Fibrosis Research Advances
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Tracheal and airway disorders
- Eosinophilic Esophagitis
- Gallbladder and Bile Duct Disorders
- Iron Metabolism and Disorders
- Healthcare cost, quality, practices
- Erythrocyte Function and Pathophysiology
- Potassium and Related Disorders
- Childhood Cancer Survivors' Quality of Life
- Stoma care and complications
- Cancer-related molecular mechanisms research
- Vascular Malformations and Hemangiomas
- Fibroblast Growth Factor Research
- Child and Adolescent Health
- Lymphatic Disorders and Treatments
- Autoimmune Bullous Skin Diseases
- Dysphagia Assessment and Management
- Sphingolipid Metabolism and Signaling
- Congenital Diaphragmatic Hernia Studies
- Metastasis and carcinoma case studies
- Child Nutrition and Feeding Issues
- Central Venous Catheters and Hemodialysis
- Cancer, Lipids, and Metabolism
Lucile Packard Children's Hospital
2025
Johns Hopkins University
2023-2024
Johns Hopkins All Children's Hospital
2023-2024
Stony Brook University
2021
Background Gastrointestinal (GI) disease in pediatric patients with cystic fibrosis (CF) is a growing concern the era of improved lung disease; however, true prevalence GI diagnoses, medical therapies, and frequency diagnostic therapeutic interventions this population have yet to be explored on multisystem scale. The aim present study was describe, among CF (PwCF) compared large cohort healthy controls, types 1) disorders; 2) medication use; 3) procedural interventions. Methods This...
Abstract Endoscopic vacuum‐assisted therapy offers an easier and safer alternative to thoracic surgery, self‐expanding stents, or esophageal clips has been shown be a promising technique for management of pediatric perforations. In this report, we present novel application percutaneous endoscopic gastrostomy‐assisted pull technique, wherein preexisting gastrostomy is reaccessed allow safe placement the vacuum sponge with more comfortable effective closure compared transnasal transoral...
Previous studies have demonstrated the safety of performing endoscopic retrograde cholangiopancreatography (ERCP) in pediatric population; however, few addressed outcomes children undergoing ERCP during acute pancreatitis (AP). We hypothesize that performed setting AP can be executed with similar technical success and adverse event profiles to those patients without pancreatitis. Using Pediatric Database Initiative, a multi-national multi-institutional prospectively collected dataset, we...
Protein-losing enteropathy (PLE) is a severe complication of the Fontan procedure that leads to systemic complications owing enteric protein loss. Hepatoduodenal lymphatic leakage resulting from increased pressure one such complication. We present case pediatric heart transplant patient who experienced refractory PLE symptoms requiring serial albumin infusions and exhibited into duodenum. Using diagnostic lymphangiography endoscopy, we identified affected area treated it successfully with...
Esophagitis dissecans superficialis (EsoDS) is a rare condition characterized by the shedding of superficial esophageal epithelium. Limited data exists on EsoDS in pediatric population. We present case 17-year-old female with chronic nausea and vomiting diagnosed EsoDS. Endoscopy revealed mucosal sloughing, histology confirmed esophagitis necrosis. underrecognized, its association psychoactive medications remains unclear. Fortunately, cases tend to resolve spontaneously without...
Breast cancer is a very heterogeneous disease, and ~30% of breast patients succumb to metastasis, highlighting the need understand mechanisms progression in order identify new molecular targets for treatment. Sphingosine kinase 1 (SK1) has been shown be upregulated with cancer, several studies have suggested its involvement and/or mostly based on cell studies. In this work we evaluated role SK1 development metastasis using transgenic model, mouse mammary tumor virus-polyoma middle...
A high-fat diet (HFD) and obesity are risk factors for many diseases including breast cancer. This is particularly important with close to 40% of the current adult population being overweight or obese. Previous studies have implicated that Mediterranean diets (MDs) partially protect against However, date, links between cancer progression not well defined. Therefore, begin define assess this, we used an isocaloric control (CD) two HFDs enriched either olive oil (OOBD, high in oleate,...
Mauer, Tian MD, MS; Trocchia, Carolena MD; Collard, Michael Chandler, Nicole M. Poulos, Nicholas Wilsey, MD Author Information