A5084848134- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Retinal Imaging and Analysis
- Ocular Diseases and Behçet’s Syndrome
- Ophthalmology and Eye Disorders
- Craniofacial Disorders and Treatments
- Cerebrovascular and genetic disorders
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Health and Risk Factors
- Ocular Disorders and Treatments
- Intraocular Surgery and Lenses
- Cerebrovascular and Carotid Artery Diseases
- Dermatological and Skeletal Disorders
- Ocular Infections and Treatments
- Poisoning and overdose treatments
- Electroconvulsive Therapy Studies
- Cardiovascular Syncope and Autonomic Disorders
- Acute Ischemic Stroke Management
- Axon Guidance and Neuronal Signaling
- Vascular Malformations Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Ocular and Laser Science Research
Royal Bournemouth Hospital
2023-2025
University Hospitals Dorset NHS Foundation Trust
2023-2024
University College London
2022
Moorfields Eye Hospital
2022
Royal Derby Hospital
2021
Leicester Royal Infirmary
2019-2020
University Hospitals of Leicester NHS Trust
2019
University of Southampton
2018
University Hospital Southampton NHS Foundation Trust
2018
Importance X-linked retinitis pigmentosa (XLRP) is a severe cause of early-onset RP in male individuals, characterized by degeneration photoreceptors, an extinguished electroretinogram, and vision loss. Objective To assess the duration improvements retinal sensitivity associated with single, subretinal injection cotoretigene toliparvovec (BIIB112/AAV8-RPGR) gene therapy after vitrectomy surgery dosed eye over 12 months part 1 Clinical Trial Retinal Gene Therapy for Retinitis Pigmentosa Using...
Aims/Purpose: To present the annual rates of post‐intravitreal injection endophthalmitis at Royal Bournemouth Hospital (RBH) over an eight‐year period from 01/02/2016 until 31/01/2024. Methods: The total number intravitreal injections performed was identified retrospectively our electronic records. cases post‐injection were department's written logbook record. Results: Over above 8‐year‐period, a 13 identified. this 8‐year‐period 54,134. fluctuated minimum 0% (year 31/01/20217) to maximum...
Aim: Angioid streaks (ASs) are a rare retinal condition and compromise visual acuity when complicated with choroidal neovascularization (CNV). They represent crack-like dehiscences at the level of Bruch’s membrane. This objective narrative review aims to provide an overview pathophysiology, current treatment modalities, future perspectives on this condition. Materials Methods: A literature search was performed using “PubMed”, “Web Science”, “Scopus”, “ScienceDirect”, “Google Scholar”,...
Purpose: To describe long-term outcomes with intravitreal Bevacizumab for choroidal neovascularization secondary to Sorsby fundus dystrophy. Materials/methods: Observational case series. Results: Two sisters of the same family formally diagnosed dystrophy were followed-up 12 years. The elder sister (S1) presented significant decline in vision due her right eye (OD). She developed 3 years later left (OS). was treated injections on a pro-re-nata (PRN) until April 2015, when treat-and-extend...
To describe long term follow-up in a family with GUCY2D dominant cone dystrophy.Optical coherence tomography scans and fundus autofluorescence images were obtained. Flash pattern electroretinograms (ERGs) occipital reversal visual evoked potentials recorded.Two members of the same (father son) identified to have heterozygous R838C mutation gene. The father presented at age 45 bilateral bull's eye maculopathy temporal disc pallor. Over 13y serial follow up visits, progressed gradually into...
I am writing this letter to present three case series of choroidal neovascular (CNV) membrane after macular surgery, which responded poorly intravitreal injections anti-vascular endothelial growth factors (anti-VEGF).This is an observational series.The cases were identified from our electronic medical record (Medisoft).Visual acuity assessment and complete ophthalmic examination including multimodal imaging performed.Multimodal included color fundus photographs, optical coherence tomography...
Abstract Introduction: To describe an unusual case of binasal congruous hemianopia secondary to functional visual loss (FVL). Patient concerns: A 24 year-old male was referred originally by his optician at the Emergency Eye Department Leicester Royal Infirmary in October 2018 with field changes affecting nasal vision both eyes on routine eye examination. The patient reported ongoing headaches over last 6 weeks 8 associated simultaneous peripheral changes. He also rapid weight same period...
This is a case of bilateral and symmetric postoperative pseudophakic cystoid macular edema (CME) in patient with telangiectasia type 2 after uneventful subsequent cataract surgeries. An 80-year-old woman history had phacoemulsification procedures developed CME during the early periods, remarkably both eyes. The responded well to treatment topical antiinflammatory drops (combination steroids nonsteroidal drugs [NSAIDs] prescribed for right eye NSAIDs only left eye), resolved some months. To...
Vitreomacular traction (VMT) is an ocular condition which involves the vitreoretinal interface, and characterised as incomplete posterior vitreous detachment with residual adhesions of vi...
The aim of this article is to provide a concise synopsis Horizontal Gaze Palsy and Progressive Scoliosis syndrome give the ophthalmologist’s perspective. rare autosomal recessive genetic condition. It has been described in both consanguineous non-consanguineous families. caused by mutations round-about guidance receptor 3 (ROBO3) gene. Based on our literature review, date, roughly 100 patients with 55 gene have reported. age onset symptoms varies from 2 months up 60 years, but usually start...
Abstract Rationale: Horizontal Gaze Palsy and Progressive Scoliosis syndrome (HGPPS) is a very rare autosomal recessive disorder that has been reported mainly in consanguineous families. Our aim was to describe case of HGPPS pediatric patient. Patient concerns: A 3-year-old male child referred our ophthalmology clinic because squint since he 6 months old. His parents were concerned both eyes gradually became more esotropic over the past year. In addition, unable walk independently undergoing...