To present clinical results regarding the treatment of patients with age-related macular degeneration (neovascular form) after implementation a 'virtual' type follow-up in single retina service centre.Retrospective study based on records Leicester Royal Infirmary Retina department. Two periods were compared, 2-year period 2011-2012 and following one 2012-2013 when clinics model applied Primary outcomes as follows: time between two appointments, or number significant (>15 letters) improvement...

To determine the time-dependent toxicity of Trypan blue at 0.06% concentration in cultured human trabecular meshwork cells.Human cells vitro were exposed to and acute was evaluated. Cells for 5, 30, 60 s 15, min a commercially available preparation (Vision Blue; DORC International Zuidland, The Netherlands). Morphology observed by phase-contrast microscopy cell viability measured using Hoechst 33342 (Intergen; Purchase, NY, USA) propidium iodide assays percentage living dead...

The occurrence and severity of corneal oedema after phacoemulsification is dependent on the integrity endothelial cells. function these cells affected by diabetes mellitus consequently behaviour cornea in diabetic patients special interest.To compare frequency two age-matched groups diabetics non that underwent cataract surgery Ophthalmology Department Xanthi General Hospital Greece.A retrospective case control study was conducted a fashion. Patients were assessed regarding at three...

To evaluate the clinical effectiveness and analyze outcomes of a treat-and-extend (T&E) treatment regimen with ranibizumab for wet age-related macular degeneration (ARMD) in real life settings over first 2 years (24 months) treatment.Retrospective analysis visual acuity, spectral domain optical coherence tomography (SD-OCT) parameters burden data 56 eyes 54 unselected naive patients diagnosed exudative ARMD. Monthly injections were offered until no signs disease activity such as...

To determine the long-term functional and anatomical outcome of idiopathic uveitic cystoid macular edema (UCME).A longitudinal retrospective study was undertaken medical records patients with UCME. All individuals were examined in uveitis Service at Moorfields Eye Hospital. The main measures change visual acuity UCME diverse time points.A total 109 eyes (92 patients) included analysis. Mean follow-up 60 ± 45 months (median, 48 months). logarithm minimum angle resolution 1 month after...

To investigate the effect of binocularity on long-term visual acuity in patients who have undergone bilateral implantation a presbyopia-correcting diffractive multifocal intraocular lens (IOL).Twenty (9 men and 11 women) with an average age 70 ± 7 years (range: 56 to 78 years) underwent IOL (AcrySof IQ ReSTOR IOL, SN60D3; Alcon Laboratories, Inc., Fort Worth, TX). Uncorrected was measured monocularly binocularly 26 6 months following second eye 17 40 months) using University Crete...

L- and M-cone driven on- off- ERG responses their interactions were examined using full field stimuli with sawtooth temporal profiles. The effects of frequency contrast studied. recordings obtained from 21 trichromatic, 1 protanopic, deuteranopic subjects. ERGs to L-cone increments decrements resembled those increments, respectively (i.e., the opposite polarity). Temporal had little effect on implicit times. All response components varied linearly contrast. When stimulated simultaneously,...

Conventional medical curriculum is the rule of teaching in Greek Medical Schools. students are often taught irrelevant details with little or no reference to their potential clinical significance. Alternatively, integrated warrants that complete material covered by each faculty member not considering areas personal expertise. The aim this study was evaluate implementation ophthalmic training.The main outcome measures retrospective were a) comments and recommendations made anonymously...

To investigate the possible toxic effect of air exposure for an in vitro model primary human corneal endothelial cells (HCECs).Primary HCECs were isolated from donor rings and cultivated at 37°C 5% CO2 95% humidified air. Six groups HCEC cultures set up, 4 samples enclosed each group: group 1 consisted which exposed to 30 minutes. Group 2 hour, 3 hours, 6 5 12 24 hours.Three hours after exposure, morphology was still intact; however, a few within monolayer appeared enlarged exhibited...

Collagen cross-linking using UV-A irradiation combined with the photosensitizer riboflavin is a new technique for treating progressive keratoconus. The purposes of this study were to examine whether primary human corneal keratocytes (HCKs) are capable expressing and secreting fibronectin tissue transglutaminase (tTgase), an enzyme extracellular matrix protein, tTgase increased after treatment HCK cells (RFUV-A), thus providing another possible physiological mechanism pathway.Cell cultures...

To study the incidence and risk factors for retinal pigment epithelium tears following intravitreal anti-vascular endothelial growth factor (VEGF) injections.Retrospective longitudinal study. 4027 anti-VEGF injections in 628 patients (676 eyes) choroidal neovascularisation associated with age related macular degeneration a period of 18 months were studied.Seventeen (mean 83.95±5.84) developed tears. The rate was 0.4%. Fibrovascular detachment (PED) previously observed all cases. In 88 %...

AbstractDiscoid lupus erythematosus is a common form of chronic cutaneous erythematosus, an autoimmune inflammatory disease that affects most the human organs, including skin, kidneys, joints, heart and lungs. We describe 45‐year‐old Caucasian woman with 21‐year history eyelid redness irritation. She had been treated antibiotics, steroids hygiene, therapy resulted to brief periods relief symptoms. In last 12 months, her symptoms seemed have exacerbated, despite administration local therapy....

Background andobjectives: The aim of this study was to examine via electron microscopy the lens epithelial cells in age-related cataracts and compare findings between patients with without exfoliation syndrome, Greek population. Materials Methods: Twenty-one cataracts, older than 60 years, were included study. Eleven them also suffered from syndrome. Anterior capsules, obtained during phacoemulsification, examined a transmission microscope. Results: In all cases, ultrastructural features...

Purpose To evaluate the alterations in morphology and elemental composition of reusable phacoemulsification tips after cleaning sterilization. Setting John A. Moran Eye Center, Salt Lake City, Utah, USA. Design Experimental study. Methods For main experiment, 2 types needles were studied. One tip each type underwent 1, 2, 3 autoclave sterilizations with use detergents followed by thorough rinsing sterile water between cycles. Another set same procedure but without rinsing. Subsequently,...

Purpose To assess the ultrastructural morphologic changes in surface's micro-roughness for single-use and multiple-use phaco tips after multiple phacoemulsification cycles an ex vivo animal model. Setting John A. Moran Eye Center Utah Nanofab, College of Engineering, University Utah, Salt Lake City, USA. Design Experimental study. Methods Eight types were studied using identical experimental protocol. Two each type used to emulsify porcine cataractous lenses moderate hardness 2 minutes. This...