A5058749372- RNA modifications and cancer
- Moringa oleifera research and applications
- Ferroptosis and cancer prognosis
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- Diverse Scientific Research Studies
- Antibiotic Resistance in Bacteria
- MicroRNA in disease regulation
- Pharmaceutical and Antibiotic Environmental Impacts
- Phytochemicals and Antioxidant Activities
- Phytochemistry and Bioactivity Studies
- Identification and Quantification in Food
- Fungal Biology and Applications
- Advanced biosensing and bioanalysis techniques
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Bioinformatics and Genomic Networks
- Cancer, Lipids, and Metabolism
University of Rajshahi
2019-2023
University of Toyama
2022-2023
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death globally. The mechanisms underlying development HCC are mostly unknown till now.The main goal this study was to identify potential drug target proteins and agents for treatment HCC.The publicly available three independent mRNA expression profile datasets were downloaded from NCBI-GEO database explore common differentially expressed genes (cDEGs) between control samples using Statistical LIMMA approach....
Abstract Cervical cancer (CC) is considered as the fourth most common women globally.that shows malignant features of local infiltration and invasion into adjacent organs tissues. There are several individual studies in literature that explored CC-causing hub-genes (HubGs), however, we observed their results not so consistent. Therefore, main objective this study was to explore hub HubGs (hHubGs) might be more representative compare single based HubGs. We reviewed 52 published articles found...
Nowadays, the spread of antibiotic-resistant Escherichia coli (E. coli) from food animals to humans is considered be a serious public health problem. The aim study was determine prevalence multidrug-resistant ESBL-producing E. isolated beef and sheep meat. A total 400 meat samples (200 200 sheep) were randomly collected different slaughterhouses wet markets in Habiganj, Sylhet, Moulvibazar Sunamganj districts Sylhet division Bangladesh. Among samples, 136 (90 46 sheep). Disc diffusion...
Angiotensin Converting Enzyme (ACE) regulates blood pressure.ACE converts angiotensin I to II which binds with its receptors and through a cascade of reactions constrict vesels, consequently results in increased pressure, called hypertension.Inhibition ACE activity is considered as an useful therapeutic target that reduce hypertension.Moringa oleifera leaves have traditionally been used Ayurvedic medicine for their antihypertensive effect Moringa was reported on spontaneously hypertensive...
Cancer is one of the vital causes morbidity and mortality worldwide recognized as second most leading cause death.Considering side effects high cost synthetic anticancer drugs, plant might act a source novel agents with better host safety.In this investigation, Moringa oleifera leaves methanolic extract (MOLME) was subjected to evaluate its antiproliferative effect molecular mechanism in Ehrlich ascites carcinoma (EAC) cells Swiss albino mice.MOLME inhibited EAC cell growth approximately 64%...
Background: Adverse side effects of currently available therapies against cancer, leads scientists to find effective compounds from natural sources. Objective: In the present study, stem-bark Mycelia champaca is subjected evaluate its antiproliferative effect Ehrlich Ascites Carcinoma (EAC) cells. To date, anti-proliferative M. bark extract EAC cell line has not been reported elsewhere. Therefore, we intended investigate potential cells in vivo. Methods: vivo anticancer activity was...
Naturally occurring ribozymes with a modular architecture are promising platforms for construction of RNA nanostructures because redesign enables their oligomerization. The resulting can exhibit the catalytic function parent ribozyme in an assembly dependent manner. In this study, we designed and constructed open-form oligomers bimolecular form RNase P ribozyme. were analyzed biochemically by atomic force microscopy (AFM).
The multimolecular assembly of three-dimensionally structured proteins forms their quaternary structures, some which have high geometric symmetry. size and complexity protein structures often increase in a hierarchical manner, with simpler, smaller serving as units for larger structures. In this study, we exploited oligomerization ribozyme cyclic trimer to achieve ribozyme-based RNA assembly. By installing kissing loop (KL) interacting one-, two-, or three-unit molecules the trimer,...