A5084928452- Statistical Methods in Clinical Trials
- Statistical Methods and Bayesian Inference
- Advanced Causal Inference Techniques
- Optimal Experimental Design Methods
- Behavioral Health and Interventions
- Musculoskeletal pain and rehabilitation
- Health Systems, Economic Evaluations, Quality of Life
- Statistical Methods and Inference
- Smoking Behavior and Cessation
- Advanced Multi-Objective Optimization Algorithms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- School Health and Nursing Education
- Child and Adolescent Psychosocial and Emotional Development
- Obesity, Physical Activity, Diet
- Pain Management and Placebo Effect
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Economic and Environmental Valuation
- Neural and Behavioral Psychology Studies
- Health and Wellbeing Research
- Geriatric Care and Nursing Homes
- Bayesian Methods and Mixture Models
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Dementia and Cognitive Impairment Research
Maastricht University
2016-2025
Maastricht University Medical Centre
2005-2022
Institute of Directors
2012
Roessingh Research and Development
2005
Utrecht University
2003
Pierre Fabre (France)
1995
Mediolanum Farmaceutici (Italy)
1995
Radboud University Nijmegen
1989
The Verbal Learning Test (VLT; Rey, 1958) evaluates the declarative memory. Despite its extensive use, it has been difficult to establish normative data because test administration not uniform. purpose of present study was gather for VLT a large number (N = 1855) healthy participants aged 24-81 years, using procedure in which words be learned were presented either verbally or visually. results showed that performance decreased an age-dependent manner from early age. learning capacity younger...
The Stroop Color-Word Test was administered to 1,856 cognitively screened, healthy Dutch speaking participants aged 24 81 years. effects of age, gender, and education on test performance were investigated adequately stratify the normative data. results showed that especially speed-dependent scores (time complete a subtest), rather than accuracy measures (the errors made per sub-task), profoundly affected by demographic variables. In addition main variables, an Age Low Level Education...
Several cognitive-behavioral factors contribute to the persistence of pain disability in patients with chronic back pain. Fear-avoidance beliefs and fear movement/(re)injury particular have been shown be strong predictors physical performance disability. Patients reporting substantial pain-related might benefit from exposure vivo a set individually tailored, fear-eliciting, hierarchically ordered movements rather than more general graded activity.Six consecutive low who reported were...
Since pain-related fear may contribute to the development and maintenance of chronic low back pain (CLBP), an exposure in vivo treatment (EXP) was developed for CLBP patients. We examined effectiveness as well specific mediating mechanisms EXP versus operant graded activity (GA) directly 6 months post-treatment a multi-centre randomized controlled trial. In total, 85 patients suffering from disabling non-specific reporting at least moderate were randomly allocated or GA. It demonstrated that...
The Letter Digit Substitution Test (LDST) is based on earlier developed substitution tests (e.g., Symbol Test) but uses over-learned signs instead of the symbols used in other tests. written and oral versions LDST were administered to a large, cognitively screened sample (N = 1,858) adults aged 24 81 years. Age was most important predictor performance, females outperformed males. A low level education profoundly influenced performance: effect versus high performance comparable about 20 years...
Previous research has indicated that performance on verbal fluency tests (VFTs) is influenced by language and/or culture. Consequently, normative VFT data for English-speaking people cannot be used whom English not their first language. The aim of the present study was to provide Animal Naming, Profession and Letter M Naming (four-letter words beginning with letter ) VFTs Dutch-speaking populations, based a large sample ( N = 1856) healthy men women aged 24–81 years different educational...
PURPOSE To compare outcomes after laparoscopic versus open major liver resection (hemihepatectomy) mainly for primary or metastatic cancer. The outcome measure was time to functional recovery. Secondary included morbidity, quality of life (QoL), and those with cancer, margin status adjuvant systemic therapy. PATIENTS AND METHODS This a multicenter, randomized controlled, patient-blinded, superiority trial on adult patients undergoing hemihepatectomy. Patients were recruited from 16 hospitals...
A randomized trial was conducted to study the impact of individualized computer-generated nutrition information and additional effects iterative feedback on changes in intake fat, fruits, vegetables. Respondents experimental group received letters tailored their dietary intake, intentions, attitudes, self-efficacy expectations, self-rated behavior. After first letter, half behavior intentions. The control a single general letter format similar letters. Computer-tailored had significantly...
The Concept Shifting Test (CST) is a newly developed Trail Making Type test that measures concept shifting and executive functioning. purpose of the present study was to determine whether CST performance affected by age, gender, educational level, or handedness establish normal range performance. administered large sample (N = 1,794) cognitively intact adults (age 24 81 years). results showed superior in women, decreased with increased level education. Handedness did not affect Normative...
Background: The μ ‐opioid receptor gene ( OPRM1 ) codes for the receptor, which binds β ‐endorphin. A118G polymorphism in this affects ‐endorphin binding such that Asp40 variant (G allele) 3 times more tightly than common Asn40 (A allele). This study investigated influence of on cue reactivity after exposure to an alcoholic beverage male heavy drinkers. Methods: Participants were either homozygous A allele n =84) or carrying at least 1 copy G =24). All participants took part a cue‐reactivity...
The pretest-posttest control group design can be analyzed with the posttest as dependent variable and pretest covariate (ANCOVA) or difference between (CHANGE). These 2 methods give contradictory results if groups differ at pretest, a phenomenon that is known Lord's paradox. Literature claims ANCOVA preferable treatment assignment based on randomization questionable for preexisting groups. Some literature suggests paradox has to do measurement error in pretest. This article shows two new...
To investigated the effectiveness of an adherence intervention (AIMS) designed to fit HIV-clinics' routine care procedures.Through block randomization, patients were allocated or control group. The study included 2 months baseline measurement, 3 intervention, and 4 follow-up. HIV-nurses delivered a minimal ("adherence sustaining") scoring >95% at baseline, intensive improving") with <95% adherence. Control participants received high-quality usual care.Electronically monitored viral load.133...
Understanding the gap between people's intentions and actual health behavior is an important issue in psychology. Our aim this study was to investigate whether self-regulatory processes (monitoring goal progress responding discrepancies) mediate intention-behavior relation HIV medication adherence (Study 1) intensive exercise 2).In Study 1, questionnaire electronically monitored data were collected at baseline 3 months later from patients control arm of HIV-adherence intervention study. In...
Objectives: There is preliminary evidence for the efficacy of positive psychology interventions pain management. The current study examined effects an internet-based self-help program patients with chronic musculoskeletal and compared it cognitive-behavioral program. Materials Methods: A randomized controlled trial was carried out 3 conditions: internet-delivered program, waitlist control. total 276 were to 1 conditions posttreatment data obtained from 206 patients. Primary outcomes...
The present study aimed to develop norms for the Tampa Scale Kinesiophobia (TSK), a frequently used measure of fear movement/(re)injury. Norms were assessed TSK total score as well scores on previously proposed activity avoidance and somatic focus scales. Data from Dutch, Canadian, Swedish pain samples (N=3082). established using multiple regression obtain more valid reliable than can be obtained by subgroup analyses based age or gender. In Dutch (N=2236), diagnosis was predictive all More...
Laparoscopic left lateral sectionectomy (LLLS) has been associated with shorter hospital stay and reduced overall morbidity compared open (OLLS). Strong evidence not, however, provided.