Elemir Simko

ORCID: 0000-0003-0954-7398
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About
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Research Areas
  • Insect and Pesticide Research
  • Plant and animal studies
  • Insect and Arachnid Ecology and Behavior
  • Aquaculture disease management and microbiota
  • Clostridium difficile and Clostridium perfringens research
  • Viral gastroenteritis research and epidemiology
  • Animal health and immunology
  • Escherichia coli research studies
  • Veterinary Oncology Research
  • Veterinary Equine Medical Research
  • Physiological and biochemical adaptations
  • Bee Products Chemical Analysis
  • Virus-based gene therapy research
  • Bacterial Identification and Susceptibility Testing
  • Animal Virus Infections Studies
  • Respiratory viral infections research
  • Veterinary medicine and infectious diseases
  • Infectious Diseases and Mycology
  • Neonatal Respiratory Health Research
  • Metabolism and Genetic Disorders
  • Infant Nutrition and Health
  • Selenium in Biological Systems
  • Anesthesia and Pain Management
  • Cancer Research and Treatments
  • Orthopedic Infections and Treatments

University of Saskatchewan
2015-2025

Saskatchewan Ministry of Agriculture
2022

Government of Saskatchewan
2022

Agriculture and Agri-Food Canada
2022

Western University of Health Sciences
2000-2020

National Research Council Canada
2015

Institute for Biological Sciences
2015

Diagnostic Services Manitoba
2015

The University of Melbourne
2015

Cambridge University Press
2009

Necrotic enteritis, caused by Clostridium perfringens type A, is more prevalent in broilers fed wheat or barley diets than those a corn diet. We compared the effects of wheat, and on vitro proliferation C. A. Bacteria were inoculated into supernatants delivered from either digested non-digested barley, mixed with thioglycollate medium (1:3). Colony forming units counted following incubation for 6 h at 40°C. There no significant differences clostridial among diets. Bacterial was significantly...

10.1080/0307945021000024544 article EN Avian Pathology 2002-12-01

Feline mammary carcinoma is highly malignant and generally associated with a poor prognosis, although studies suggest the range of survival times in affected cats broad. Histologic grading these tumors achieved using Elston Ellis system, originally developed for human breast cancer. In cats, however, classification this method has variable prognostic value. Therefore, objectives study were (1) to evaluate system feline predominantly spayed population (2) determine whether modification or...

10.1177/0300985814543198 article EN Veterinary Pathology 2014-07-24

Abstract European foulbrood (EFB) is a disease of honey bee larvae caused by Melissococcus plutonius . In North America, oxytetracycline (OTC) approved to combat EFB though tylosin (TYL) and lincomycin (LMC) are also registered for use against American disease. Herein, we report characterize an OTC-resistant M. isolate from British Columbia, Canada, providing antimicrobial sensitivity the three antibiotics studying their abilities alter larval survival in vitro infection model. Specifically,...

10.1038/s41598-022-09796-4 article EN cc-by Scientific Reports 2022-04-07

The present study involved a comparative analysis of the effects purified flaxseed lignans, secoisolariciresinol diglucoside (SDG) and its aglycone metabolite (SECO), in hyperlipidaemic rats. For hypercholesterolaemia, female Wistars (six rats per group) were fed standard or 1 % cholesterol diet orally administered 0, 3 6 mg SDG/kg 1·6 3·2 SECO/kg body weight once daily for 4 weeks. Hypertriacylglycerolaemia was induced male Sprague–Dawley (ten by supplementing tap water with 10 fructose....

10.1017/s0007114508207488 article EN British Journal Of Nutrition 2009-02-16

Development of a successful in vitro rearing protocol has been essential for pesticide safety assessment immature honey bee workers under laboratory conditions. In contrast, testing drones is limited, part due to the lack protocols this reproductive caste. Considering that healthy are mating and reproduction queen, standardized necessary support studies, as well gain deeper understanding drone development. Using established workers, we modified days grafting pupal transfer, diet volume,...

10.1371/journal.pone.0314859 article EN cc-by PLoS ONE 2025-02-13

The majority of infections, including those caused by respiratory syncytial virus (RSV), occur at mucosal surfaces. As no RSV vaccine is available our goal to produce an effective subunit with adjuvant suitable for delivery and cross-presentation. A truncated secreted version the fusion (ΔF) protein formulated polyI : C, innate defence regulator peptide polyphosphazene, induced local systemic immunity, affinity maturation F-specific IgG, IgA virus-neutralizing antibodies, CD8 + T-cells in...

10.1099/vir.0.058461-0 article EN Journal of General Virology 2013-10-18

Thiamethoxam, clothianidin, and imidacloprid are the most commonly used neonicotinoid insecticides on Canadian prairies. There is widespread contamination of nectar pollen with neonicotinoids, at concentrations which sublethal for honey bees (Apis mellifera Linnaeus).

10.1371/journal.pone.0190517 article EN cc-by PLoS ONE 2018-01-02

Mammary carcinomas and adenocarcinomas (MACs) are relatively common tumors in cats. The postexcisional survival period of affected cats is inversely proportional to tumor size, but the reported median periods for different size categories quite variable. This variability diminishes prognostic value data. In our study, with MACs greater than 3 cm diameter had a 12-month period, whereas those less 21-month period. Survival smaller ranged from 54 months; therefore, alone limited diameter....

10.1111/j.1751-0813.2002.tb11342.x article EN Australian Veterinary Journal 2002-12-01

Deformed wing virus (DWV) is a single-stranded RNA of honey bees ( Apis mellifera L.) transmitted by the parasitic mite Varroa destructor. Although DWV represents major threat to bee health worldwide, pathological basis infection not well documented. The objective this study was investigate clinicopathological and histological aspects natural in workers. Emergence worker observed 5 colonies that were clinically affected with newly emerged collected for histopathology. DWV-affected 2 times...

10.1177/0300985819834617 article EN Veterinary Pathology 2019-03-11

Neonicotinoid and fungicide exposure has been linked to immunosuppression increased susceptibility disease in honeybees (Apis mellifera). European foulbrood, caused by the bacterium Melissococcus plutonius, is a of honeybee larvae which causes economic hardship for commercial beekeepers, particular those whose colonies pollinate blueberries. We report first time Canada, an atypical variant M. plutonius isolated from blueberry-pollinating colony. With this isolate, we used vitro larval...

10.3390/insects11040252 article EN cc-by Insects 2020-04-17

Introduction Blueberry producers in Canada depend heavily on pollination services provided by honey bees ( Apis mellifera L.). Anecdotal reports indicate an increased incidence of European foulbrood (EFB), a bacterial disease caused Melissococcus plutonius, is compromising and colony health. Fungicidal products are commonly used blueberry production to prevent fungal diseases such as anthracnose botrytis fruit rot. Pesticide exposure has been implicated bee immunosuppression; however, the...

10.3389/fevo.2023.1073775 article EN cc-by Frontiers in Ecology and Evolution 2023-01-30

(1) Background: Microsporidiosis (nosemosis) is an intestinal disorder of adult honey bees caused by the microsporidian pathogens Vairimorpha apis and ceranae. In Canada, fumagillin approved antibiotic used to treat this disease. However, recommended dosage based on efficacy studies for V. apis, native pathogen in European bees. Since detection ceranae Apis mellifera, became more prevalent managed seems have replaced due yet unknown reasons. (2) Methods: This colony study investigated...

10.3390/life14030373 article EN cc-by Life 2024-03-12

The productivity and survival of honey bee ( Apis mellifera) colonies depend on queen health. Colony-level neonicotinoid exposure has negative effects reproductive fitness queens. However, it is unclear if the observed are a direct outcome toxicity or result from suboptimal care developing queens by exposed workers. aim this study was to evaluate larval survival, fitness, histopathology incremental doses (0, 5, 50 ng) thiamethoxam (THI) applied directly individual late larvae (7 days...

10.1177/03009858211031845 article EN cc-by-nc Veterinary Pathology 2021-07-16

A massive fish kill affecting exclusively common carp ( Cyprinus carpio carpio) in the St. Lawrence River, Québec, Canada, during summer of 2001 was investigated by use laboratory diagnostic methods and an attempt to experimentally induce disease. The ultimate causes mortality were opportunistic bacterial infections with Aeromonas hydrophila Flavobacterium sp. secondary immunosuppression induced physiologic (i.e., spawning) environmental high temperatures low water levels) stressors,...

10.1354/vp.43-3-302 article EN Veterinary Pathology 2006-05-01

A 10-year-old spayed female Golden Retriever was admitted with chronic lameness of the right hind limb. tibial plateau leveling osteotomy (TPLO) had been performed on this leg approximately three years previously. progressively growing soft tissue mass, affecting stifle, previously treated TPLO biopsied and found to be a histiocytic sarcoma. Previously proposed links between development neoplasia in stifle region presence synovitis, osteotomy, orthopaedic implants, specifically Slocum plate,...

10.3415/vcot-07-05-0054 article EN Veterinary and Comparative Orthopaedics and Traumatology 2008-01-01
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