Tomohiko Yamane

ORCID: 0000-0003-0955-4272
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About
Contact & Profiles
Research Areas
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer, Hypoxia, and Metabolism
  • Advanced MRI Techniques and Applications
  • Medical Imaging and Pathology Studies
  • Radiopharmaceutical Chemistry and Applications
  • MRI in cancer diagnosis
  • Cardiac Imaging and Diagnostics
  • Lymphoma Diagnosis and Treatment
  • Lanthanide and Transition Metal Complexes
  • Nanoplatforms for cancer theranostics
  • Advanced X-ray and CT Imaging
  • Cancer Treatment and Pharmacology
  • Gastric Cancer Management and Outcomes
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Dementia and Cognitive Impairment Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Lung Cancer Diagnosis and Treatment
  • Drug Transport and Resistance Mechanisms
  • Cancer, Lipids, and Metabolism
  • Cardiac tumors and thrombi
  • Cancer Research and Treatments
  • Alzheimer's disease research and treatments
  • Glioma Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations

Saitama Medical University
2015-2025

Kobe City Medical Center General Hospital
2022-2025

Saitama Medical University Hospital
2019-2023

Foundation for Biomedical Research and Innovation
2009-2016

Saitama International Medical Center
2015-2016

Universitätsklinikum Würzburg
2016

Institute for Biomedical Research and Innovation
2011-2014

University of Würzburg
2014

IHI Corporation (United States)
2013

Daiyukai General Hospital
2002-2008

Eribulin mesylate (eribulin) is a first-in-class halichondrin B-based microtubule dynamics inhibitor. To compare the anti-angiogenic activity of eribulin to that bevacizumab, we compared tumour vessel remodelling and reoxygenation between two agents. Patients with advanced breast cancer stage III/IV were eligible for study. assigned receive either or single-agent bevacizumab. Tissue concentrations oxyhaemoglobin (O2Hb) deoxyhaemoglobin (HHb), oxygen saturation (SO2) tumours before day 7...

10.1038/bjc.2016.122 article EN cc-by-nc-sa British Journal of Cancer 2016-05-01

To investigate the improvement of prognostication active bone metastatic burden by discriminating metastases from degenerative changes in hot foci, using skeletal standardized uptake values (SUVs) quantitative single photon emission tomography/computed tomography (SPECT/CT) patients with prostate cancer.We investigated 170 cancer who underwent SPECT/CT 99mTc-methylene-diphosphonate (MDP), through conjugate gradient reconstruction tissue zoning, attenuation, and scatter corrections applied,...

10.1186/s41824-017-0006-y article EN cc-by European Journal of Hybrid Imaging 2017-10-11

Purpose: Bevacizumab, an antibody against endothelial growth factor, is a key but controversial drug in the treatment of metastatic breast cancer. We, therefore, aimed to determine intrinsic resistance bevacizumab at physiologic and molecular levels advanced cancer using PET, dynamic contrast-enhanced MRI, diffuse optical spectroscopic imaging (DOSI), multiplex cytokine assays.Experimental Design: In total, 28 patients diagnosed with stage III/IV receiving single-agent for 1 week followed by...

10.1158/1078-0432.ccr-17-0874 article EN Clinical Cancer Research 2017-07-06

10.1007/s00259-009-1302-y article EN European Journal of Nuclear Medicine and Molecular Imaging 2009-11-13

<h3>BACKGROUND AND PURPOSE:</h3> The role of <sup>18</sup>F-FDG-PET in the diagnosis Alzheimer disease is increasing and should be validated. aim this study was to assess inter-rater variability interpretation images obtained Japanese Alzheimer9s Disease Neuroimaging Initiative, a multicenter clinical research project. <h3>MATERIALS METHODS:</h3> This analyzed 274 scans (67 mild disease, 100 cognitive impairment, 107 normal cognitive) as baseline for which were acquired with various types...

10.3174/ajnr.a3665 article EN cc-by American Journal of Neuroradiology 2013-08-01

This study aimed to evaluate the quality and associated quantitative values of bone single-photon emission computed tomography (SPECT) with without SwiftScan using a semiconductor camera equipped cadmium-zinc-telluride detector.

10.22038/aojnmb.2024.76919.1543 article EN PubMed 2025-01-01

Hypoxia is a key driver of cancer progression. We evaluated the prognostic impact 18F-fluoromisonidazole (FMISO) prior to treatment in patients with breast cancer.Forty-four stage II/III primary underwent positron emission tomography/computed 18F-fluorodeoxyglucose (FDG-PET/CT) and FMISO. After measurement by FDG-PET/CT, tissue-to-blood ratio (TBR) was obtained using FMISO-PET/CT. FMISO-TBR compared for correlation clinicopathological factors, disease-free survival (DFS), overall (OS)....

10.1186/s13058-018-0970-6 article EN cc-by Breast Cancer Research 2018-07-27
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