Clarissa L. B. Frandsen

ORCID: 0000-0003-0956-9765
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About
Contact & Profiles
Research Areas
  • Ovarian function and disorders
  • Ovarian cancer diagnosis and treatment
  • Reproductive Biology and Fertility
  • Pituitary Gland Disorders and Treatments
  • Colorectal Cancer Screening and Detection
  • Assisted Reproductive Technology and Twin Pregnancy
  • Cancer Risks and Factors
  • Glioma Diagnosis and Treatment
  • Genetic factors in colorectal cancer
  • Cardiovascular and exercise physiology
  • Colorectal Cancer Surgical Treatments
  • Endometrial and Cervical Cancer Treatments
  • Muscle metabolism and nutrition
  • Physical Activity and Health
  • Reproductive System and Pregnancy
  • Meningioma and schwannoma management
  • Reproductive Health and Technologies

Danish Cancer Society
2022-2025

Gentofte Hospital
2023-2025

Steno Diabetes Centers
2025

University of Copenhagen
2025

Herlev Hospital
2022-2024

Cancer Institute (WIA)
2024

Copenhagen University Hospital
2022

Most previous studies found an elevated risk of endometrial cancer among women with polycystic ovary syndrome (PCOS). However, these had highly varying methods for ascertainment PCOS diagnoses and limitations such as few exposed short follow-up. In this cohort study, we investigated the association between born in Denmark January 1, 1940, December 31, 1993 (n = 1 719 121). Data including covariates, were derived from nationwide registers. We used Cox proportional hazards regression models to...

10.1093/aje/kwae061 article EN American Journal of Epidemiology 2024-05-16

Abstract An association between polycystic ovary syndrome (PCOS) and epithelial ovarian tumors is biologically plausible as conditions inherent to PCOS such excessive androgenic hormones, reproductive factors obesity are also risk for these hormone‐sensitive tumors. However, previous studies have showed conflicting results various methodological limitations. This population‐based cohort study investigates the includes all women born in Denmark January 1, 1940 December 31, 1993 (n = 1 719...

10.1002/ijc.34574 article EN International Journal of Cancer 2023-06-26

In response to M. Naylor's valuable critique of our study "Polycystic Ovary Syndrome and Endometrial Cancer Risk: Results from a Nationwide Cohort Study," we recognize the merit in suggested areas. We that including information on hormone therapy may have added understanding relationship between polycystic ovary syndrome (PCOS) endometrial cancer risk. further acknowledge importance frequency gynecological visits, which treated as mediator rather than confounder, given its role reflecting...

10.1093/aje/kwaf026 article EN American Journal of Epidemiology 2025-03-04

Abstract Objective To examine the separate and combined effects of low-volume high-intensity interval training (HIIT) walking compared with no on insulin sensitivity skeletal metabolic capacity in individuals prediabetes. Design Individuals were randomized to: (1) control (no exercise), (2) HIIT (3 × 20 s's cycle sprint 3 times weekly), (3) + (walking >10 000 steps/day), or (4) for 12 weeks. Methods Insulin was assessed by an oral glucose tolerance test at baseline end-of-trial....

10.1093/ejendo/lvaf004 article EN European Journal of Endocrinology 2025-03-27

<title>Abstract</title> <bold>Purpose</bold>: Although some reproductive and metabolic characteristics of polycystic ovary syndrome (PCOS) are known risk factors for breast cancer, the evidence regarding a potential association between PCOS cancer is scarce. In this population-based cohort study including all 1 719 452 women born in Denmark 1940 1993, we investigated cancer. <bold>Methods</bold>: diagnoses, covariates, migrations vital status were obtained from national population- health...

10.21203/rs.3.rs-3921144/v1 preprint EN cc-by Research Square (Research Square) 2024-02-06

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.99.p93 article EN Endocrine Abstracts 2024-05-06

Abstract Study question Is polycystic ovary syndrome (PCOS) associated with epithelial ovarian cancer and borderline tumors? Summary answer Overall, no association between PCOS tumors was seen, however, we observed an increased risk of among postmenopausal women PCOS. What is known already Few studies have investigated the tumors. In general, reported conflicting results, possibly due to methodological differences varying confounder adjustments. For cancer, most associations, while two for...

10.1093/humrep/dead093.012 article EN Human Reproduction 2023-06-01

Abstract Study question Is the use of fertility drugs among infertile women associated with tumors central nervous system (CNS)? Summary answer The most specific types is not an increased risk CNS overall. What known already Few previous studies have investigated association between and tumors. Studies reported inconsistent results regarding assisted reproductive technologies such as in vitro fertilization (IVF). No various drugs. design, size, duration Retrospective population-based cohort...

10.1093/humrep/deac104.097 article EN Human Reproduction 2022-06-29
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