Jacob T. Ramsey

ORCID: 0000-0003-0966-3292
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About
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Research Areas
  • Pediatric Hepatobiliary Diseases and Treatments
  • Congenital Anomalies and Fetal Surgery
  • Inflammation biomarkers and pathways
  • Apelin-related biomedical research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Atherosclerosis and Cardiovascular Diseases

Vanderbilt University Medical Center
2021

Objective: Animal models of atherosclerosis are used extensively to interrogate molecular mechanisms in serial fashion. We tested whether a novel systems biology approach integration preclinical data identifies pathways and regulators human disease. Approach Results: Of 716 articles published ATVB from 1995 2019 using the apolipoprotein E knockout mouse study atherosclerosis, were extracted 360 unique studies which gene was experimentally perturbed impact plaque size or composition analyzed...

10.1161/atvbaha.121.317071 article EN Arteriosclerosis Thrombosis and Vascular Biology 2021-11-11
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