Prajwal Gyawali

ORCID: 0000-0003-0975-5576
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About
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Research Areas
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Blood properties and coagulation
  • Stroke Rehabilitation and Recovery
  • Adipokines, Inflammation, and Metabolic Diseases
  • Liver Disease Diagnosis and Treatment
  • Acute Ischemic Stroke Management
  • Lipoproteins and Cardiovascular Health
  • Physical Activity and Health
  • Cardiovascular and exercise physiology
  • Birth, Development, and Health
  • Diabetes Management and Research
  • Lipid metabolism and disorders
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Pregnancy and preeclampsia studies
  • Erythrocyte Function and Pathophysiology
  • Dialysis and Renal Disease Management
  • Tuberculosis Research and Epidemiology
  • Cardiac Health and Mental Health
  • Mental Health Treatment and Access
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Folate and B Vitamins Research
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Musculoskeletal pain and rehabilitation
  • Chronic Disease Management Strategies
  • Chronic Kidney Disease and Diabetes

Charles Sturt University
2012-2024

University of Southern Queensland
2020-2024

Novena University
2024

Hunter Medical Research Institute
2020-2023

Baker Heart and Diabetes Institute
2021

Australian Catholic University
2021

University of Newcastle Australia
2019-2021

Janssen (Switzerland)
2021

Florey Institute of Neuroscience and Mental Health
2021

Hunter New England Local Health District
2021

Background Cardiorespiratory fitness (CRF) is an important marker of current and future health status. The primary aim our study was to evaluate the impact a time-efficient school-based intervention on older adolescents’ CRF. Methods Two-arm cluster randomised controlled trial conducted in two cohorts (February 2018 February 2019 2020) New South Wales, Australia. Participants (N=670, 44.6% women, 16.0±0.43 years) from 20 secondary schools: 10 schools (337 participants) were Burn 2 Learn...

10.1136/bjsports-2020-103277 article EN cc-by-nc British Journal of Sports Medicine 2020-12-21

Stroke survivors report significant levels of psychological distress post stroke. To date, most studies conducted have focused on the relationship between stress and functional outcomes in acute phase However, no had considered role over chronic phase, where may continue to exert negative effects cognitive processes. Further, potentially modulatory variables, such as resilience, stroke has been understudied. The purpose this study was consider relationships resilience with long-term People...

10.3389/fneur.2020.00230 article EN cc-by Frontiers in Neurology 2020-04-22

ObjectiveWe have shown increased whole blood viscosity (WBV), decreased erythrocyte deformability, and aggregation in metabolic syndrome (MetS) our previous study. The objective of the study was to find out if altered hemorheology MetS is associated with chronic inflammation oxidative stress same subjects.MethodsOne hundred recruited participants were classified into three groups based on number components present following National Cholesterol Education Program, Adult Treatment Panel III...

10.1179/1351000214y.0000000120 article EN Redox Report 2014-12-12

Community health workers, also known as extension workers (HEWs), play an important role in promotion. This study evaluates HEWs’ knowledge, attitude, and self-efficacy for non-communicable diseases (NCD) HEWs (n = 203) completed a structured questionnaire on behaviour, NCD risk perception. Regression analysis was used to determine the association between perception with knowledge (high, medium, low), attitude (favourable/unfavourable) physical activity (sufficient/insufficient). higher were...

10.3390/ijerph20095642 article EN International Journal of Environmental Research and Public Health 2023-04-25

Introduction This trial aims to investigate the impact of a school-based physical activity programme, involving high-intensity interval training (HIIT), on physical, mental and cognitive health senior school students. Methods analysis The Burn 2 Learn (B2L) intervention will be evaluated using two-arm parallel group cluster randomised controlled with allocation occurring at level (to treatment or wait-list control). Schools recruited in two cohorts from New South Wales, Australia. aim...

10.1136/bmjopen-2018-026029 article EN cc-by-nc BMJ Open 2019-05-01

Circadian rhythms are evolutionarily programmed biological that primarily entrained by the light cycle. Disruption of circadian is an important risk factor for several metabolic disorders. Photoperiod defined as total duration exposure in a day. With extended use indoor/outdoor light, smartphones, television, computers, and social jetlag people exposed to excessive artificial at night increasing their photoperiod. Importantly long photoperiod not limited any geographical region, season, age,...

10.1016/j.metabol.2023.155770 article EN cc-by Metabolism 2023-12-29

Whole blood viscosity (WBV) is the intrinsic resistance to flow developed due frictional force between adjacent layers of flowing blood. Elevated WBV an independent risk factor for stroke. Poor microcirculation elevated can prevent adequate perfusion brain and might act as important secondary hypoperfusion in acute ischaemic In present study, we examined association with basal cerebral assessed by CT Confirmed ischemic stroke patients (n = 82) presenting hours were recruited from single...

10.1007/s10072-021-05666-5 article EN cc-by Neurological Sciences 2021-10-20

Whole-blood viscosity (WBV) depends on vascular geometry and blood physiological constituents. Diabetes mellitus, hypertension, dyslipidemia obesity – the major components of metabolic syndrome (MetS) can independently affect vessels microcirculation. MetS is state oxidative stress systemic inflammation. Pro-oxidant inflammatory cytokines induce endothelial dysfunction. Morphological alterations erythrocytes could be a consequence decreased deformability, These events altogether lead to...

10.2217/clp.12.65 article EN Clinical Lipidology 2012-12-01

Binod Kumar Yadav, M.Sc., Rajesh Gupta, B.Sc., Prajwal Gyawali, Rojeet Shrestha, Bibek Poudel, Manoj Sigdel, and Bharat Jha, M.Sc.. Korean J Lab Med 2011;31:95-7. https://doi.org/10.3343/kjlm.2011.31.2.95

10.3343/kjlm.2011.31.2.95 article EN cc-by-nc Annals of Laboratory Medicine 2011-04-01

High sensitivity C-reactive protein (hsCRP) has been associated with metabolic syndrome (MetS) and its components. Several studies have suggested hsCRP to be used as a marker for the primary prevention of cardiovascular diseases. So, we aimed evaluate association between levels components MetS in diabetic non-diabetic population.

10.7860/jcdr/2014/8085.4522 article EN cc-by-nc-nd JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2014-01-01

The prediabetes and cardiovascular complications studies proposes to develop a screening protocol for diabetes risk, strategies holistic management amongst others. Over 500 participants were recruited in the first 2 years of rural community research screening. Specific this report, various published findings reviewed. objective is summarize outcomes itemize limitations as they constitute basis future directions. Affordability availability are major confounding behavioural change wheel...

10.1186/s13104-017-3017-7 article EN cc-by BMC Research Notes 2017-12-01

The present study compares the association of Metabolic Syndrome (MetS) with hemorheological parameters, oxidative stress, inflammation and peripheral arterial disease markers. 100 participants were recruited divided into three groups on basis absence or presence MetS its components. Odds ratio for correctly predicting was highest erythrocyte aggregation followed by deformability. ROC curve analysis demonstrated that all components significantly classified participants. Area Under Curve...

10.3233/ch-152033 article EN Clinical Hemorheology and Microcirculation 2016-11-04

Introduction: Preeclampsia is a pregnancy-specific complication that significantly contributes to maternal and perinatal morbidity mortality worldwide, even more so in developing countries such as Nepal. The potential contribution of dyslipidemia elevated levels oxidized low-density lipoprotein (oxLDL) the pathogenesis preeclamptic pregnancies has been observed several studies. aim this study was compare lipid profile parameters particularly oxLDL between healthy also correlate with other...

10.2147/ijwh.s117850 article EN cc-by-nc International Journal of Women s Health 2016-10-01
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