A5003435827- Genetics, Aging, and Longevity in Model Organisms
- Birth, Development, and Health
- Spaceflight effects on biology
- Animal Behavior and Reproduction
- Circadian rhythm and melatonin
- Telomeres, Telomerase, and Senescence
- Genetic and phenotypic traits in livestock
- Insect-Plant Interactions and Control
- Insect symbiosis and bacterial influences
- Sperm and Testicular Function
- Zoonotic diseases and public health
- Bat Biology and Ecology Studies
- bioluminescence and chemiluminescence research
- Mosquito-borne diseases and control
- Insect and Pesticide Research
- Fish Ecology and Management Studies
- Evolutionary Psychology and Human Behavior
- 3D Printing in Biomedical Research
- Wildlife Ecology and Conservation
- Neuroendocrine regulation and behavior
- Biocrusts and Microbial Ecology
- Evolutionary Game Theory and Cooperation
University of Edinburgh
2020-2025
Uppsala University
2018-2019
is an important model for antiviral immunity in arthropods, but very few DNA viruses have been described from the family Drosophilidae. This deficiency limits our opportunity to use natural host-pathogen combinations experimental studies, and may bias understanding of
Abstract Classical theory maintains that ageing evolves via energy trade-offs between reproduction and survival leading to accumulation of unrepaired cellular damage with age. In contrast, the emerging new postulates because deleterious late-life hyper-function reproduction-promoting genes excessive biosynthesis in late-life. The uniquely predicts optimizing nutrient-sensing molecular signaling adulthood can simultaneously postpone increase Darwinian fitness. Here, we show reducing...
Early-life adversity influences adult fitness across vertebrate species. In polygynous systems with intense intrasexual competition, males may be more sensitive to conditions experienced during development. However, the importance of different aspects early-life environment and how their effects differ between sexes remains poorly understood. Here, we used a long-term study wild Soay sheep characterize in terms weather, infection risk, resource competition maternal investment, test...
Understanding within-population variation in aging rates across different phenotypic traits is a central focus of biogerontological studies. Early evolutionary models predict that natural selection acts to cause all deteriorate simultaneously. However, observations provide evidence for widespread patterns asynchronous laboratory and populations. Recent verbal put forth explain such argue because senescence costly fitness, should are most important fitness senesce slower than less related...
Telomere length (TL), typically measured across a sample of blood cells, has emerged as an exciting potential marker physiological state and the costs investment in growth reproduction within evolutionary ecology. While there is mounting evidence from studies wild vertebrates that short TL predicts raised subsequent mortality risk, relationship between reproductive less clear cut, previous report both negative positive associations. In this study, we examined different aspects maternal...
Early- versus late-life trade-offs are a central prediction of life-history theory that expected to shape the evolution ageing. While ageing is widely observed in wild vertebrates, evidence early-late influence rates remains limited. Vertebrate reproduction complex, multi-stage process, yet few studies have examined how different aspects early-life reproductive allocation performance and Here, we use longitudinal data from 36-year study Soay sheep show predicts trait-dependent manner....
Telomere length (TL) is a biomarker hypothesized to capture evolutionarily and ecologically important physiological costs of reproduction, infection immunity. Few studies have estimated the relationships among status, immunity, TL fitness in natural systems. The hypothesis that short telomeres predict reduced survival because they reflect costly consequences immune investment remains largely untested. Using longitudinal data from free-living Soay sheep population, we tested whether leucocyte...
Abstract Early-life adversity influences adult fitness across a range of vertebrates. In polygynous systems with intense intrasexual competition, males may be more sensitive to conditions experienced during growth and development. However, the relative importance different aspects early environment how their effects differ between sexes remain poorly understood. Here, we used long-term study wild Soay sheep characterise early-life in terms weather, infection, resource competition maternal...
Abstract Drosophila melanogaster is an important model for antiviral immunity in arthropods, but very few DNA viruses have been described from the family Drosophilidae. This deficiency limits our opportunity to use natural host-pathogen combinations experimental studies, and may bias understanding of virome. Here we report fourteen detected a metagenomic analysis approximately 6500 pool-sequenced , sampled 47 European locations between 2014 2016. These include three new Nudiviruses,...
Abstract Classical theory maintains that ageing evolves via energy trade-offs between reproduction and survival leading to accumulation of unrepaired cellular damage with age. In contrast, the emerging new postulates because deleterious late-life hyper-function reproduction-promoting genes excessive biosynthesis in late-life. The uniquely predicts optimizing nutrient-sensing molecular signalling adulthood can simultaneously postpone increase Darwinian fitness. Here we show reducing...