A5065927560- Hemophilia Treatment and Research
- Blood Coagulation and Thrombosis Mechanisms
- Chronic Myeloid Leukemia Treatments
- Primary Care and Health Outcomes
- Orthopaedic implants and arthroplasty
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Healthcare cost, quality, practices
- Musculoskeletal Disorders and Rehabilitation
- Healthcare Quality and Management
- Innovations in Medical Education
- Coaching Methods and Impact
- Mentoring and Academic Development
- Healthcare Policy and Management
- Cardiac Health and Mental Health
Beaumont Hospital
2024
Multiple Sclerosis Society
2016-2020
Severe haemophilia is associated with major psychological and economic burden for patients, caregivers, the wider health care system. This has been quantified documented a number of European countries in recent years. However, few studies have taken standardised methodology across multiple simultaneously, sought to amalgamate all three levels severe disease. The overall aim 'Cost Haemophilia Europe: Socioeconomic Survey' (CHESS) study was capture annualised psychosocial five countries. A...
Joint damage remains a major complication associated with haemophilia and is widely accepted as one of the most debilitating symptoms for persons severe haemophilia. The aim this study to describe how complications such target joints influence health-related quality life (HRQOL).Data on hemophilia patients without inhibitors were drawn from 'Cost Haemophilia across Europe - Socioeconomic Survey' (CHESS) study, cost-of-illness assessment in A B five European countries (France, Germany, Italy,...
Target joints are a common complication of severe haemophilia. While factor replacement therapy constitutes the majority costs in haemophilia, relationship between target and non drug-related direct (NDDCs) has not been studied. Data on haemophilia patients without inhibitors was drawn from 'Cost Haemophilia across Europe – Socioeconomic Survey' (CHESS) study, cost assessment A B five European countries (France, Germany, Italy, Spain, United Kingdom) which 139 specialists provided...
Purpose: Congenital hemophilia A and B are bleeding disorders characterized by deficiency of factors VIII IX, respectively. This study aimed to collect health-related quality-of-life (HRQoL) health-utility data from patients with differing disease severity. Methods: Individuals aged ≥12 years living in France or the UK completed a series questionnaires, including EQ-5D-3L -5L SF-36 version 2. Association demographic clinical variables was explored using linear regression, comparison Pearson...
Clinical severity and impact of haemophilia on quality life have been generally considered to be lower for B (HB) compared with A (HA) patients.To compare annual bleeding rate (ABR), target joint development health-related (HRQoL) between adult (≥18 years) severe HA HB patients using recent data from the Cost Haemophilia in Europe: a Socioeconomic Survey (CHESS) study.Multivariate generalized linear models (GLM) were constructed assess relationship type, ABR, HRQoL (derived EQ-5D index...
Abstract Background Muscle strengthening exercises have the potential to improve outcomes for boys with haemophilia, but it is unclear what types of exercise might be benefit. We elicited views health‐care professionals, and their families create assess a home‐based muscle programme. Objective To design develop programme professionals aimed at improving musculoskeletal health, refine intervention by engaging haemophilia (Study 1). Following delivery, qualitatively evaluate feasibility...
Introduction Haemophilia is a rare, inherited disorder in which blood does not clot normally, resulting bleeding into joints and muscles. Long-term consequence disabling joint pain, stiffness, muscle weakness, atrophy reduced mobility. The purpose of this proposed feasibility randomised controlled trial (RCT) to test the an age-appropriate physiotherapy intervention designed improve strength, posture way boys use their during walking everyday activities. Methods analysis A small-scale...
Describes how the Buckinghamshire Medical Audit Advisory Group have approached introduction of medical audit in primary care. Outlines original facilitator model, which proved so successful encouraging initiatives coronary heart disease prevention, is now being used to encourage and promote quality using techniques. Explores use cycle emphasizes importance teamwork enabling change occur. special personal professional skills required work increasingly complex dynamic arena care, with a...
Abstract Background/Introduction Cardiac rehabilitation (CR) is an outpatient chronic disease management model recommended in clinical practice guidelines for patients with all forms of atherosclerotic cardiovascular diseases (ASCVD). Nutrition counselling a core component the prevention non-communicable including disease. While striving to deliver care line guidelines, it equally important communicate nutritional information accessible way which accommodates varying degrees health literacy....