A5057231354- Microbial Community Ecology and Physiology
- Food composition and properties
- Methane Hydrates and Related Phenomena
- Polysaccharides Composition and Applications
- Genomics and Phylogenetic Studies
- Anaerobic Digestion and Biogas Production
- Microbial Metabolites in Food Biotechnology
- Bacteriophages and microbial interactions
- Plant and animal studies
- RNA modifications and cancer
- Insect and Arachnid Ecology and Behavior
- Polar Research and Ecology
- Ovarian cancer diagnosis and treatment
- Cryospheric studies and observations
- Enzyme Production and Characterization
- Biofuel production and bioconversion
- Insect and Pesticide Research
- Liver Disease Diagnosis and Treatment
- Climate change and permafrost
- Endometrial and Cervical Cancer Treatments
- Gut microbiota and health
- Nanocomposite Films for Food Packaging
- Microbial Fuel Cells and Bioremediation
- Genomics, phytochemicals, and oxidative stress
- Intraperitoneal and Appendiceal Malignancies
Lanzhou University
2021-2025
Xinjiang Medical University
2019-2025
First Affiliated Hospital of Xinjiang Medical University
2019-2025
Beijing University of Civil Engineering and Architecture
2024-2025
Global Health Research Center of Central Asia
2025
First Affiliated Hospital of Harbin Medical University
2025
Max Planck Institute for Terrestrial Microbiology
2017-2024
Shandong Academy of Sciences
2018-2024
Qilu University of Technology
2018-2024
Jiangsu University
2024
Abstract Microbial and viral communities transform the chemistry of Earth's ecosystems, yet specific reactions catalyzed by these biological engines are hard to decode due absence a scalable, metabolically resolved, annotation software. Here, we present DRAM (Distilled Refined Annotation Metabolism), framework translate deluge microbiome-based genomic information into catalog microbial traits. To demonstrate applicability across diverse genomes, evaluated performance on defined, in silico...
Summary Syntrophic interaction occurs during anaerobic fermentation of organic substances forming methane as the final product. H 2 and formate are known to serve electron carriers in this process. Recently, it has been shown that direct interspecies transfer ( DIET ) for syntrophic CH 4 production from ethanol acetate. Here, we constructed paddy soil enrichments determine involvement butyrate oxidation production. The results showed was significantly accelerated presence nano Fe 3 O all...
Abstract Neonatal cholestasis is a potentially life-threatening condition requiring prompt diagnosis. Mutations in several different genes can cause progressive familial intrahepatic cholestasis, but known cannot account for all cases. Here we report four individuals from two unrelated families with neonatal and mutations NR1H4 , which encodes the farnesoid X receptor (FXR), bile acid-activated nuclear hormone that regulates acid metabolism. Clinical features of severe, persistent -related...
To determine whether the addition of cisplatin-based chemotherapy (CT) to pelvic radiation therapy (RT) will improve survival early-stage, high-risk patients with cervical carcinoma.
X-linked acrogigantism (X-LAG) is a new syndrome of pituitary gigantism, caused by microduplications on chromosome Xq26.3, encompassing the gene GPR101, which highly upregulated in tumors. We conducted this study to explore clinical, radiological, and hormonal phenotype responses therapy patients with X-LAG syndrome. The included 18 (13 sporadic) microduplication Xq26.3. All sporadic cases had unique duplications inheritance pattern two families was dominant, all Xq26.3 duplication carriers...
Abnormal metabolism and uncontrolled angiogenesis are two important characteristics of malignant tumors. The occurrence both events involves many key molecular changes including miRNA. However, EBV encoded miRNAs rarely mentioned as capable regulating tumor angiogenesis. Here, we reported that one the by EBV, EBV-miR-Bart1-5P, can significantly promote nasopharyngeal carcinoma (NPC) cell glycolysis induces in vitro vivo. Mechanistically, EBV-miR-Bart1-5P directly targets α1 catalytic subunit...
Glycerol-plasticized high-amylose corn starch/konjac glucomannan (HCS/KGM) composite films incorporated with various concentrations of β-cyclodextrin (β-CD) were prepared and investigated for structural, mechanical, physical properties. The results X-ray diffraction, attenuated total reflectance Fourier transform infrared spectroscopy, thermogravimetric analyses, scanning electron microscopy indicated that β-CD excluded from the polymer chains aggregated to form crystals during film...
Caloric excess and sedentary lifestyles have led to an epidemic of obesity, metabolic syndrome, non-alcoholic fatty liver disease (NAFLD). The objective this study was investigate the mechanisms underlying high fat diet (HFD)-induced NAFLD, explore NRF2 activation as a strategy alleviate NAFLD.
The association between sleep-related disorders and inflammation has been demonstrated in previous studies. systemic immune-inflammation index (SII) is a novel inflammatory based on leukocytes, but its relationship with disorder unclear. We aimed to investigate the SII nationally representative nonhospitalized sample.Data were obtained from 2005-2008 National Health Nutrition Examination Survey (NHANES). Exposure variables included self-reported disorders, such as sleep duration, problems,...
Maintaining ideal cardiovascular health (CVH) is believed to have potential anti-aging benefits. The American Heart Association (AHA) recently updated the "Life's Essential 8 (LE8)" metrics measure CVH, but its connection with protein klotho still unclear. We aimed explore relationship between and serum in a nationally representative US middle-aged older population. A cross-sectional study. National Health Nutrition Examination Survey (2007−2016). total of 9457 participants. Ideal CVH scores...
Glioblastomas multiforme (GBM) are the most frequently occurring malignant brain cancers. Treatment for GBM consists of surgical resection and subsequent adjuvant radiation therapy chemotherapy. Despite this, patient survival is limited to 12-15 months, researchers continually trying develop improved options. Insulin-like growth factor 2 mRNA-binding protein (Imp2) known be upregulated in many cancers regulate signaling activity insulin-like (IGF2). However, relatively little about its role...
Propionate is one of the major intermediary products in anaerobic decomposition organic matter wetlands and paddy fields. Under methanogenic conditions, propionate decomposed through syntrophic interaction between proton-reducing propionate-oxidizing bacteria H(2)-consuming methanogens. Temperature an important environmental regulator; yet its effect on oxidation has been poorly understood. In present study, we investigated a rice field soil at 15°C 30°C. [U-(13)C]propionate (99 atom%) was...
De novo missense variants in CDK13 have been described as the cause of syndromic congenital heart defects seven individuals ascertained from a large cardiovascular malformations cohort. We aimed to further define phenotypic and molecular spectrum this newly disorder. To minimise ascertainment bias, we recruited nine additional with pathogenic clinical research exome laboratory sequencing cohorts. Each individual underwent dysmorphology exam comprehensive medical history review. demonstrate...