Geronimo P. Tapia

ORCID: 0000-0003-1004-3189
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About
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Research Areas
  • Neurogenesis and neuroplasticity mechanisms
  • Adipose Tissue and Metabolism
  • Stress Responses and Cortisol
  • Nerve injury and regeneration
  • Regulation of Appetite and Obesity
  • Protein Tyrosine Phosphatases
  • Melanoma and MAPK Pathways
  • Neuroscience of respiration and sleep
  • Biochemical effects in animals
  • Ginger and Zingiberaceae research
  • Fibroblast Growth Factor Research
  • Neuroendocrine regulation and behavior

The University of Texas at El Paso
2021-2024

Recent studies indicate that central administration of oxytocin (OT) reduces body weight (BW) in high fat diet-induced obese (DIO) rodents by reducing energy intake and increasing expenditure (EE). Previous our lab have shown OT into the fourth ventricle (4V; hindbrain) elicits loss stimulates interscapular brown adipose tissue temperature (TIBAT) DIO rats. We hypothesized OT-elicited stimulation sympathetic nervous system (SNS) activation IBAT contributes to its ability activate BAT reduce...

10.3389/fddev.2024.1497746 article EN cc-by Frontiers in Drug Delivery 2024-12-03

Rodent studies indicate that impaired glucose utilization or hypoglycemia is associated with the cellular activation of neurons in medulla (Winslow, 1733) (MY), believed to control feeding behavior and counterregulation. However, such has been tracked primarily within hours challenge, rather than sooner, poorly mapped standardized brain atlases. Here, we report that, 15 min receiving 2-deoxy-d-glucose (2-DG; 250 mg/kg, i.v.), which can trigger glucoprivic behavior, marked elevations were...

10.3390/jcm12072483 article EN Journal of Clinical Medicine 2023-03-24

Abstract Recent studies indicate that central administration of oxytocin (OT) reduces body weight (BW) in high fat diet-induced obese (DIO) rodents by reducing energy intake and increasing expenditure (EE). Previous our lab have shown OT into the fourth ventricle (4V; hindbrain) elicits loss stimulates interscapular brown adipose tissue temperature (T IBAT ) DIO rats. We hypothesized OT-elicited stimulation sympathetic nervous system (SNS) activation contributes to its ability activate BAT...

10.1101/2024.09.12.612710 preprint EN public-domain bioRxiv (Cold Spring Harbor Laboratory) 2024-09-13

Abstract Rodent studies indicate that impaired glucose utilization or hypoglycemia is associated with cellular activation of neurons in the medulla ( Winslow, 1733 ) (MY) believed to control feeding behavior and counterregulation. However, such has been tracked primarily within hours challenge, rather than sooner, poorly mapped standardized brain atlases. Here, we report 15 min receiving 2-deoxy-D-glucose (2-DG; 250 mg/kg, i.v.), which can trigger glucoprivic behavior, marked elevations were...

10.1101/2022.08.30.504809 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-09-01

Abstract The rostral ventrolateral medulla (RVLM), a part of the medullary reticular formation, plays major role in several physiological responses, including cardiovascular and sympathetic nervous system functions. Although aging causes disturbances responses these systems, RVLM involvement age-related changes is not clear. Previous work using high-throughput gene expression analysis aged animals suggested that chemical neurotransmission-related genes might be downregulated with advancing...

10.1101/2022.12.14.520496 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-12-15

The rostral ventrolateral medulla (RVLM), a part of the medullary reticular formation, plays major role in several physiological responses, including cardiovascular and sympathetic nervous system functions. Although aging causes disturbances responses these systems, RVLM involvement age-related changes is not clear. Previous work on high-throughput gene expression analysis aged animals suggested that neurotransmission- synapse-related genes might be downregulated (Balivada S et al., 2017....

10.1096/fasebj.2021.35.s1.05093 article EN The FASEB Journal 2021-05-01
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