- Drug-Induced Hepatotoxicity and Protection
- Chemotherapy-induced organ toxicity mitigation
- Sleep and Wakefulness Research
- Phytochemicals and Medicinal Plants
- Nephrotoxicity and Medicinal Plants
- Circadian rhythm and melatonin
- Advances in Cucurbitaceae Research
- Antibiotic Use and Resistance
- Sleep and related disorders
- Cholinesterase and Neurodegenerative Diseases
- High Altitude and Hypoxia
- Respiratory and Cough-Related Research
- Natural Antidiabetic Agents Studies
- Helicobacter pylori-related gastroenterology studies
- Physical Activity and Health
- Garlic and Onion Studies
- Ethnobotanical and Medicinal Plants Studies
- Fungal Plant Pathogen Control
- Chemotherapy-induced cardiotoxicity and mitigation
- Childhood Cancer Survivors' Quality of Life
- Phytochemistry and Biological Activities
- Natural Compound Pharmacology Studies
- Liver Disease Diagnosis and Treatment
- Pharmaceutical Quality and Counterfeiting
- Exercise and Physiological Responses
Mekelle University
2012-2021
Background: Societies in developing countries use traditional medicine as alternatives for management of pain and inflammation. The plant Cucumis ficifolius has been used Ethiopia to treat many ailments including inflammation pain. objective this study was evaluate the antinociceptive anti-inflammatory activities crude root extract solvent fractions C. ficifolius. Methods: analgesic activity evaluated with acetic acid-induced writhing, hot plate, formalin-induced paw licking tests. effect...
Globally, cardiovascular diseases (CVDs) are becoming the major cause of death. Urtica simensis is one endogenous plant which treats a wide range disease conditions including heart diseases. However, there limited information on safety and efficacy plant.To evaluate in vitro antioxidant, vivo cardioprotective activity crude extract solvent fractions leaves cyclophosphamide-induced myocardial injury.The extract, aqueous hexane fraction was evaluated based anatomical, biochemical...
Context . Croton macrostachyus Hochst. ex Delile ( Euphorbiaceae ) has been used in traditional medicine to manage heart failure and other diseases Ethiopia. Objective To evaluate the antioxidant cardioprotective activities of stem bark extract solvent fractions on cyclophosphamide‐induced cardiotoxicity rats. Materials Methods DPPH free radical scavenging assay method was determine activity whereas Sprague‐Dawley rats were activity. Except for normal control, all groups subjected...
Cyclophosphamide is an alkylating antineoplastic agent and its major limitation injury to normal tissue, leading multiple organ toxicity, including kidney, heart, liver reproductive toxicity. Croton macrostachyus (Euphorbiaceae) has been used in Ethiopian traditional medicine manage renal diseases.The present study aims assess the protective effect of stem bark extract solvent fractions on cyclophosphamide-induced nephrotoxicity rats.Nephrotoxicity was induced using cyclophosphamide 200...
Exercise induces several cardiorespiratory and hematological changes in the body. In spite of latest advancements exercise physiology, effects time-of-day on these quantities remained inconclusive. A total 2070 potential citations were identified through PubMed, MEDLINE, SPORTDiscus, EMBASE, Physical Education index Google Scholar searches. Based eligibility criteria, 17 studies for analysis. Using random effect model, overall pooled erythrocytes were, RBC= Std. MD= 0.35(95% CI, -0.008 to...