Highly enantioselective aerobic oxidative cross-coupling of 2-naphthols with broad substrate scope was achieved using an iron(salan) complex as the catalyst. Enantiomeric excesses products ranged from 87 to 95%. The reaction found be different that homocoupling under same conditions.

We examined the effects of six xanthones from pericarps mangosteen, Garcinia mangostana, on cell growth inhibition human leukemia line HL60. All displayed inhibitory effects. Among them, alpha-mangostin showed complete at 10 microM through induction apoptosis.

A cell growth inhibitory effect of drupanin and baccharin, ingredients propolis, was found in human cancer lines. These compounds induced apoptosis the cells characterized by morphological nucleosomal DNA fragmentation analysis. Their effects were less potent compared with that artepillin C, which is a known anticancer compound from propolis. Importantly, HL60 more sensitive to than Con A-stimulated peripheral blood lymphocytes, whereas potency C opposite drupanin.

When the blue-emitting crystals (<bold>1b</bold>) of Ag(<sc>i</sc>) complexes coordinated by <italic>o</italic>-bis(diphenylphosphino)benzene were ground, emitting color solid changes into green (<bold>1g</bold>). The <bold>1g</bold> returned to blue on either heating or recrystallization.

We examined the in vitro effects of benzophenone derivatives garcinol, isogarcinol, and xanthochymol on cell growth four human leukemia lines. All compounds exhibited significant suppression due to apoptosis mediated by activation caspase-3. A loss mitochondrial membrane potential was found garcinol- isogarcinol-induced apoptosis, but not xanthochymol-induced apoptosis. The inhibitory isogarcinol were more potent than that which is a well- known cytotoxic derivative.

An efficient synthetic method for the preparation of multisubstituted furans, thiophenes, and pyrroles using ynolates was developed. This novel formal [4 + 1] annulation by C2−C3 C3−C4 bond formations includes cycloaddition, cyclization, decarboxylation, dehydration as key steps.

Potassium niobate, KNbO3 (KN), ceramics were prepared by a modified conventional ceramic fabrication process to characterize their piezoelectric properties. The involving two-stage calcination (first stage at 600 °C and second 1000 °C) is very effective in obtaining KN with high density ratio >96% resistivity, ρ, of >1012 Ω·cm that are nondeliquescent. showed good properties terms the electromechanical coupling factor, k33, constant, d33, mechanical quality Qm, which 0.49, 91.7 pC/N, 325,...

The structural and spectroscopic properties of a Cu(I) complex bearing methylene-linked bis(N-heterocyclic carbene) ligand, [Cu2(μ-Me-mbim)2](PF6)2 were investigated. X-ray single crystal structure analysis revealed that the is binuclear similar to corresponding silver(I) complex. In [Cu2(μ-Me-mbim)2](PF6)2, cation–π interaction between copper adjacent carbene carbon observed. On other hand, copper–copper very weak in almost negligible solution. absorption spectrum methanol shows strong band...

Aluminum(salalen) complex 1 [salalen = half-reduced salen, salen N,N′-ethylenebis(salicylideneiminato)] was found to be a highly efficient catalyst for asymmetric oxidation of cyclic dithioacetals in the presence 30% hydrogen peroxide as an oxidant. In reaction series 2-substituted 1,3-dithianes bearing alkyl, alkenyl, alkynyl, and aryl groups substituent, trans-monoxides were obtained high yields with 19:1 → >20:1 dr (diastereomeric ratio) 98−99% ee (enamtiomeric excess). The nonsubstituted...

A few Fe–salan dimer complexes serve as catalysts for aerobic oxidative coupling (AOC) of 2-naphthols, but some others do not. X-Ray and cyclic voltammetry studies various revealed that the absence or presence double hydrogen bonding in dimers, oxidation potential monomeric species location resulting radical cation are critical factors catalytic activity iron–salan AOC.

We have developed the first general method for a stereoselective olefination of acylsilanes via ynolate anions to produce (Z)-beta-silyl-alpha,beta-unsaturated ester, which leads tri- and tetrasubstituted alkenes.

Potassium niobate, KNbO3 (KN), ceramics doped with manganese (Mn) were prepared by the conventional ceramic fabrication process to characterize their electrical properties. The difficulty in obtaining dense methods limits our knowledge of piezoelectricity this ceramic. In paper, an optimized for (over 95%) and nondeliquescent KN is described. Dielectric piezoelectric data are also presented. particular, fine properties obtained Mn-doped (KN+MnCO3x wt %: KN–Mn x), highest electromechanical...

Correlation between the photophysics and structures of three Ag(I)−bis(diphosphine) complexes ([Ag(dppbz)2]NO3 (1·NO3), [Ag(dppe)2]NO3 (2·NO3), [Ag(dppp)2]NO3 (3·NO3) (dppbz = 1,2-bis(diphenylphosphino)benzene, dppe 1,2-bis(diphenylphosphino)ethane, dppp 1,3-bis(diphenylphosphino)propane) has been investigated using temperature-dependent emission measurements electrochemical theoretical methods. All have relatively low oxidation potential, which allows metal-to-ligand charge transfer (MLCT)...

Aziridination of vinyl ketones using SESN(3) in the presence Ru(CO)-salen complex 1 provides enantiopure aziridinyl that can serve as useful chiral building blocks. A formal asymmetric synthesis (+)-PD 128907 was achieved an eight-step sequence via aziridination.

Stilbene derivatives, which are resveratrol (3,4',5-trihydroxy-trans-stilbene) oligomers ranging from monomer to tetramer, isolated Dipterocarpaceae plants were tested for their inhibitory effects against murine tyrosinase activity. The structure-activity relationships obtained in this study suggest that the double bond stilbene skeleton is critical inhibition, and also molecular size important potency.

Gnetol (2,3',5',6-tetrahydroxy-trans-stilbene), a naturally occurring compound particularly found in the genus Gnetum, had strong inhibitory effect on murine tyrosinase activity. (IC50, 4.5 microM) was stronger than kojic acid 139 as standard inhibitor for Moreover, gnetol significantly suppressed, melanin biosynthesis B16 melanoma cells.