A5025849053- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- Lung Cancer Diagnosis and Treatment
- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- Molecular Biology Techniques and Applications
- Meningioma and schwannoma management
- Esophageal Cancer Research and Treatment
- Diet and metabolism studies
- Mycobacterium research and diagnosis
- Vascular Procedures and Complications
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Bacterial Identification and Susceptibility Testing
- Neurological Disease Mechanisms and Treatments
- Pituitary Gland Disorders and Treatments
- Gastric Cancer Management and Outcomes
- Vascular Tumors and Angiosarcomas
- Carbon and Quantum Dots Applications
- Phytochemical compounds biological activities
- Neurofibromatosis and Schwannoma Cases
- Chemotherapy-related skin toxicity
- Metabolomics and Mass Spectrometry Studies
- Retinopathy of Prematurity Studies
- Esophageal and GI Pathology
Capital Medical University
2021-2025
Johns Hopkins University
2021-2025
Johns Hopkins Medicine
2024-2025
Tongren Hospital
2021-2025
Peking Union Medical College Hospital
2013-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2024
Chongqing Public Health Medical Center
2024
Chongqing Medical University
2014-2024
Beijing Tongren Hospital
2021
Union Hospital
2021
Purpose To evaluate incidence and risk factors of peripherally inserted central catheter (PICC)-related complications in cancer patients. Methods A prospective, multicenter, cohort study patients with PICC insertion was performed from February 1, 2013 to April 24, 2014. All were monitored clinic until PICCs removed. The primary endpoint removal due complications. Patient-, catheter- insertion-related analyzed univariable multivariable logistic regression analysis identify significant...
To retrospectively review the efficacy of intermittent fasting 5:2 plus program (30% energy requirements on fast days and 70% nonfasting days) in Chinese patients with overweight or obesity. This retrospective cohort study evaluated weight loss outcomes treated 12 weeks clinic. Adults obesity participated plus, daily calorie restriction (70% every day) meal replacement day, partly provided high-protein replacement) programs for weeks. The primary objective was to compare three groups....
Background: Nutrition is important for the fetal developmental programming. Nutritional deficiency in early life could increase susceptibility to many aging-related disorders including cognitive decline. Keywords: Famine, malnutrition, life, risk factor, mild impairment, dementia.
Peripherally inserted central venous catheters (PICCs) are widely used in patients with cancer. Catheter usage is one of the risk factors for thromboembolism. We aimed to scrutinize incidence and PICC-related upper extremity thrombosis (UEVT) lung cancer receiving chemotherapy.We performed a retrospective cohort study PICC insertion undergoing chemotherapy. Symptomatic PICC-UEVT was diagnosed by ultrasound. The relationship between chemotherapeutic agent exposure evaluated. Patient-,...
This cohort study examines the prevalence and outcomes of misdiagnosing dermatomyositis or clinically amyopathic diagnosis.
To identify clinical incidence, risk factors and treatment of peripherally inserted central venous catheters (PICCs)-related upper extremity thrombosis (UEVT) in breast cancer patients undergoing chemotherapy.We performed a retrospective cohort study with PICC insertion chemotherapy. PICC-related UEVT was diagnosed by ultrasound. Patient-, catheter- insertion-related were analyzed univariable multivariable logistic regression to significant independent for UEVT. The incidence also analyzed.A...
This study aims to investigate the relationship between blood-based pathologies and established risk factors for cognitive decline in community-based population of Chongqing, a region with significant aging. A total 26,554 residents aged 50 years older were recruited. Multinomial logistic regression models applied assess cognition levels. Propensity score matching linear mixed effects used evaluate key circulating biomarkers. Shared distinct MCI dementia identified. Age, lower education,...
Mitochondrial neurogastrointestinal encephalopathy (MNGIE) is characterized by significant gastrointestinal dysmotility. Early and long-term nutritional therapy highly recommended. We report a case of MNGIE in patient who was undergoing nutrition therapy. The diagnosed with serious symptom fatty liver hyperlipidemia complications, along homozygous mutation the thymidine phosphorylase (TYMP) gene (c.217G > A). To our knowledge, this first such case. Herein, we describe preventive measures for...
Abstract Background This research aimed at exploring the mechanisms of alterations metabolites and pathways in T2D from perspective metabolomics transcriptomics, as well uncovering novel drug candidate for treatment. Methods Metabolites human plasma 42 patients 45 non‐diabetic volunteers were detected by liquid chromatography‐mass spectrometer (LC‐MS). Microarray dataset transcriptome was obtained Gene Expression Omnibus (GEO) database. Kyoto Encyclopedia Genes Genomes (KEGG) database used...
The purpose of this study is to compare the effectiveness double phototherapy versus single conventional in decreasing serum bilirubin levels jaundiced neonates. Forty-two preterm infants who were less than 37 weeks' gestational age and 2000 g birthweight with nonhemolytic jaundice alternately assigned (n = 19) (Biliblanket, Ohmeda irradiance 33 35 microW/cm2/nm addition combination three or four special blue white lamps 7 9 microW/cm2/nm) 23) based on elevated first week life. Phototherapy...
Objective To evaluate the nutrition risks in Chinese elderly adults community and provide basis for malnutrition prevention.Methods The study population comprised of aged 60 years or older selected from communities. A stratified multi-stage cluster sampling method was used to investigate rural urban areas with structured questionnaire. Nutrition Screening Initiative (NSI) checklist screen nutritional status. Analyses were according age,gender,different regions,rural areas,and income.Results...
Introduction This pilot exploratory study aimed to compare the health-related quality of life (HRQOL) among patients diagnosed with different types cancer receiving peripherally inserted central catheters (PICCs). Methods A multicenter cross-section PICCs was performed from February 1, 2013 April 24, 2014. The primary objective this HRQOL in type PICC. examined based on European Organisation for Research and Treatment Cancer Quality-of-Life Questionnaire-Core 30 (EORTC QLQ-C30). Multiple...
Background: The Michigan Risk Score (MRS) was the only predicted score for peripherally inserted central venous catheters (PICC) associated upper extremity thrombosis (UEVT). Age-adjusted D-dimer increased efficiency UEVT. There were no external validations in an independent cohort. Method: A retrospective study of adult patients with PICC insertion performed. primary objective to evaluate performance MRS and age-adjusted estimating risk PICC-related symptomatic sensitivity, specificity...
Abstract Background Malnutrition is common in cancer patients. The NUTRISCORE a newly developed cancer-specific nutritional screening tool and was validated by comparison with the Patient-Generated Subjective Global Assessment (PG-SGA) Screening Tool (MST) Spain. We aimed to evaluate performance of NUTRISCORE, MST, PG-SGA estimating risk malnutrition Chinese Methods Data from an open parallel multicenter cross-sectional study 29 clinical teaching hospitals 14 cities were used. Cancer...
Background: Peripherally inserted central catheters (PICCs) are performed for medium and long term intravenous therapy. The most recent guidelines recommend the use of ultrasound-guided venipuncture to reduce surgery-related complications. In years, bedside ultrasound has also been used as evidence accuracy in tip navigation positioning. This paper is aimed investigate using with ultrasonic technique intracavitary electrocardiogram during catheterization, suggest a feasible safe standardized...
Abstract Rationale: Peripherally inserted central catheters (PICC), normally located at the lower 1/3rd of superior vena cava (SVC) and cavo-atrial junction, are commonly used in cancer patients. Persistent left (PLSVC) is a vascular anomaly, patients with which seldom research was reported about PICC implanted. After obtaining written informed consent, we present case where two successful insertions were performed 50-year-old female patient PLSVC right SVC. Patients concerns: The had...
This study analyzes two kinds of surgical methods for the treatment optic pathway gliomas (OPGs) in intraorbital segment, as well outcomes OPGs.The clinical data 86 patients with OPGs treated our center was analyzed retrospectively, and symptoms, methods, follow-up results were recorded.For nerve sheath incision performed to remove a tumor while retaining Group 1 (n=36). The simultaneously removed without group 2 (n=50). effects design on post-surgical outcome are: One patient (1/36, 2.8%)...
VEXAS (vacuoles, E1-enzyme, X-linked, autoinflammatory, somatic) syndrome is a recently characterized autoinflammatory condition driven by myeloid cell dysregulation. We report two patients with concurrent diagnoses of and autoimmune blistering diseases – pemphigus vulgaris dermatitis herpetiformis highlighting previously undescribed association between innate immune dysregulation autoantibody-mediated skin diseases.
Ulcerative colitis (UC) patients often suffer from impaired nutritional conditions. However, there are few studies focused on muscle loss in UC as well its impact therapeutic response. This study aimed to investigate the prevalence of myopenia hospitalized with active UC, analyze relationship between body composition including both skeletal and fat clinical characteristics, explore association response vedolizumab.
15577 Background: Gemcitabine monotherapy is currently accepted as a standard first-line treatment of unresectable pancreatic cancer. However, the prognosis patients with cancer still remains dismal. We performed phase II study combination chemotherapy S-1, oral fluorouracil progrug tegafur combined two modulators, 5-chloro-2, 4-dihydroxypyridine and potassium oxonate, plus gemcitabine in chemo-naïve locally advanced or metastatic to evaluate efficacy toxicity prospectively. Methods:...