A5032430288- Congenital Heart Disease Studies
- Neonatal Respiratory Health Research
- Cardiovascular Conditions and Treatments
- Non-Invasive Vital Sign Monitoring
- Hemodynamic Monitoring and Therapy
- Mechanical Circulatory Support Devices
- Optical Imaging and Spectroscopy Techniques
- Infant Development and Preterm Care
- Neuroscience of respiration and sleep
- Coronary Artery Anomalies
- Congenital heart defects research
- Congenital Diaphragmatic Hernia Studies
- Antibiotics Pharmacokinetics and Efficacy
- Child and Adolescent Psychosocial and Emotional Development
- Inflammatory Bowel Disease
- Microscopic Colitis
- Infant Health and Development
- Neonatal Health and Biochemistry
- Erythrocyte Function and Pathophysiology
- Adolescent and Pediatric Healthcare
- Maternal Mental Health During Pregnancy and Postpartum
- Pharmacogenetics and Drug Metabolism
- Chemical Reactions and Isotopes
- Vitamin D Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
Shaare Zedek Medical Center
2017-2025
Hebrew University of Jerusalem
2011-2025
Monash Children’s Hospital
2019-2022
Jerusalem College of Technology
2013
This study aimed to assess thermoregulation and humidity within the Skincubator-a novel, wearable skin-to-skin incubator designed attach caregiver. Preterm neonates (PN; born between 24 33 weeks gestational age [GA]) received care (SSC) either via Skincubator or traditional SSC (t-SSC) with continuous axillary temperature monitoring. Twenty PN were enrolled in treated Skincubator. One couple who consented during delivery subsequently revoked their consent baby was excluded from further...
Oxygen saturation in arterial blood (SaO₂) provides information about the performance of respiratory system. Non-invasive measurement SaO₂ by commercial pulse oximeters (SpO₂) make use photoplethysmographic pulses red and infrared regions utilizes different spectra light absorption oxygenated de-oxygenated hemoglobin. Because scattering optical path-lengths differ between two wavelengths, require empirical calibration which is based on extracted blood. They are still prone to error, because...
Introduction Several echocardiographic scoring systems have been developed to assess the severity of patent ductus arteriosus (PDA) shunting in preterm infants. Objective The objective this study was compare ability two different evaluate hemodynamic significance PDA and predict long-term PDA-associated morbidities. Subjects El-Khuffash cohort (previously described) derived from a multicenter, prospective, observational conducted tertiary neonatal intensive care units Ireland, Canada,...
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Personalized management of diseases by considering relevant patient features enables optimal treatment, instead according to an average patient. Precision hypertension is important, because both susceptibility complications and response treatment vary between individuals. While the use genomic proteomic personal for widespread precision not practical, other features, such as age, ethnicity, cardiovascular diseases, have been utilized in guidelines management. In medicine, more...
On average, arterial oxygen saturation measured by pulse oximetry (SpO2) is higher in hypoxemia than the true invasively (SaO2), thereby increasing risk of occult hypoxemia. In current article, measurements SpO2 on 17 cyanotic newborns were performed means a Nellcor oximeter (POx), based light with two wavelengths red and infrared regions (660 900 nm), novel POx, region (761 820 nm). The readings from POxs showed values invasive SaO2 readings, disparity increased decreasing SaO2. using...
To study paracetamol (PCM) use as first line therapy for significant patent ductus arteriosus (sPDA) closure, stratified by echocardiography.In this retrospective observational study, a prepublished score comprising PDA size and velocity, PDA:left pulmonary artery ratio, diastolic flow in main LPA, LA:Ao ratio left ventricular:aortic were included shunt severity. Successful closure was defined priori or ≥50% reduction score. Comparisons made between infants with sPDA who treated not...
The ductus arteriosus is a blood vessel that connects the pulmonary artery to descending aorta during fetal life and generally undergoes spontaneous closure shortly after birth. In premature neonates it often fails close (patent arteriosus-PDA), which can result in diversion of significant part left-ventricular cardiac output circulation. This left-to-right shunt may increase flow decrease systemic perfusion (hemodynamically PDA-hsPDA), lead severe neonatal morbidity. study objective was...
Background Cytochrome P450 1A2 (CYP1A2) is a cytochrome enzyme with pivotal role in hepatic drug metabolism. Data from CYP (−/−) mouse suggest that plays aspects of iron toxicity. The aim this study was to assess the activity relation load patients transfusion‐dependent β‐thalassaemia major. Methods 13 C‐methacetin continuous breath test performed on 30 consecutive measured by rate at which C substrate metabolized and exhaled expressed as percentage dose recovery ( PDR ) per hour. correlated...
The study aimed to assess the association of nucleated red blood cells (NRBC), a surrogate intrauterine hypoxia, and elevated pulmonic vascular resistance (E-PVR) oxygen requirement after minimally invasive surfactant therapy (MIST).Retrospective cohort preterm neonates that received MIST in single unit.NRBC were measured 65 75 (87%) administered during period. In total, 22 (34%) infants had pre-MIST echocardiography (ECHO).Neonates with NRBC (predefined as >5 × 109/L, n = 16) required...