A5100374894- Animal Disease Management and Epidemiology
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- Plant Virus Research Studies
- Vector-Borne Animal Diseases
- Horticultural and Viticultural Research
- Plant-Microbe Interactions and Immunity
- Plant and Fungal Interactions Research
- Viral Infectious Diseases and Gene Expression in Insects
- Plant Stress Responses and Tolerance
- Fermentation and Sensory Analysis
- Polysaccharides and Plant Cell Walls
- Viral Infections and Vectors
- Monoclonal and Polyclonal Antibodies Research
- Garlic and Onion Studies
- Cryptography and Data Security
- Fungal Biology and Applications
- Insect-Plant Interactions and Control
- Plant Pathogens and Fungal Diseases
- Phytochemicals and Antioxidant Activities
- Pesticide Residue Analysis and Safety
- Food Quality and Safety Studies
- Aluminum toxicity and tolerance in plants and animals
- Gut microbiota and health
- Plant Disease Resistance and Genetics
Guangzhou University of Chinese Medicine
2025
Guangdong Provincial Hospital of Traditional Chinese Medicine
2025
Henan Provincial People's Hospital
2025
Institute of Soil Science
2023-2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
Lanzhou University
2022-2023
Yunnan Agricultural University
2010-2023
Guangxi Medical University
2023
Shandong Agricultural University
2020-2023
African swine fever is a lethal hemorrhagic disease of pigs caused by virus (ASFV), which greatly threatens the pig industry in many countries. Deletion virulence-associated genes to develop live attenuated ASF vaccines considered be promising strategy. A recent study has revealed that A137R gene deletion results ASFV attenuation, but underlying mechanism remains unknown. To elucidate regulating virulence, an mutant with deleted (ASFV-ΔA137R) was generated based on wild-type HLJ/2018 strain...
ABSTRACT Many viruses trigger the type I interferon (IFN) pathway upon infection, resulting in transcription of hundreds interferon-stimulated genes (ISGs), which define antiviral state host. Classical swine fever virus (CSFV) is causative agent classical (CSF), a highly contagious viral disease endangering pig industry many countries. However, anti-CSFV ISGs are poorly documented. Here we screened 20 that commonly induced by IFNs against CSFV lentivirus-delivered cell lines, identification...
ABSTRACT Classical swine fever virus (CSFV) is the causative agent of classical (CSF), a highly contagious, economically important viral disease in many countries. The E rns and E2 envelope glycoproteins are responsible for binding to entry into host cell by CSFV. To date, only one cellular receptor, heparan sulfate (HS), has been identified as being involved CSFV attachment. HS also present on surface various cells that nonpermissive Hence, there must be another receptor(s) unidentified...
African swine fever is a lethal hemorrhagic disease of global concern that caused by virus (ASFV). Despite extensive research, there exist relevant gaps in knowledge the fundamental biology viral life cycle.
As one of the most serious diseases in grape, downy mildew caused by Plasmopara viticola is a worldwide grape disease. Much effort has been focused on improving susceptible grapevine resistance, and wild resistant species are important for germplasm improvement commercial cultivars. Using yeast two-hybrid screen followed series immunoprecipitation experiments, we identified voltage-dependent anion channel 3 (VDAC3) protein from Vitis piasezkii 'Liuba-8' as an interacting partner VpPR10.1...
Negative plant-soil feedback (NPSF) due to the buildup of soilborne pathogens in soil is a major obstacle sustainable agricultural systems. Beneficial rhizosphere microfloras are recruited by plants, and mediating this has become strategic priority manipulate plant health. Here, we found that foliar infection Panax notoginseng Alternaria panax changed from negative positive. Foliar modified microbial community reversed direction pathogen Ilyonectria destructans beneficial microbes, including...
The capsid (C) protein of the Flaviviridae family members is involved in nucleocapsid formation and virion assembly. However, influence C protein-interacting partners on outcome pestivirus infections poorly defined. In this study, hemoglobin subunit beta (HB) was identified as a protein-binding by glutathione S-transferase pulldown subsequent mass spectrometry analysis PK-15 cells, which are permissive cells for classical swine fever virus (CSFV). Coimmunoprecipitation confocal microscopy...
The downy mildew disease in grapevines is caused by Plasmopara viticola. This poses a serious threat wherever viticulture practiced. Wild Vitis species showing resistance to P. viticola offer promising pathway develop new grapevine cultivars resistant which will allow reduced use of environmentally unfriendly fungicides. Here, transmission and scanning microscopy was used compare the responses three genotypes V. davidii var. cyanocarpa, piasesezkii pseudoreticulata suceptible vinifera...
Zinc deficiency could lead to a dynamic variation in gut microbial composition and function animals. However, how zinc affects the microbiome school-age children remains unclear. The purpose of this study was profile shifts with deficiency, determine whether such are associated dietary intake. A survey, anthropometric measurements, serum tests were performed on 177 children, 67 selected explore community using amplicon sequencing. School-age suffered from poor diversity insufficient food...
To develop a rational and standardized traditional Chinese medicine (TCM) good practice recommendation (GPR) methodology model that guides the formulation of recommendations grounded in clinical experience. We adopted an exploratory sequential mixed-method to by coding systematically collected literature on TCM guidelines related GPR using best-fit framework synthesis. Then based real-world data (published guidelines), saturation tests, structural rationality validation, discriminability...
In this study, we aimed to determine the transcriptomic profile of plasma cell mastitis (PCM) and elucidate its underlying mechanisms using nanopore sequencing technology (ONT). Through comparisons analyses redundantly removed transcripts with known reference genome annotations, identified 39,408 novel 20,980 genes. By exploring full-length transcriptome data, characterized selective splicing, polyadenylation events, simple sequence repeat (SSR) site information, which enhanced our...
Classical swine fever (CSF) is a highly contagious disease of caused by classical virus (CSFV). For decades the has been controlled in China modified live vaccine (C-strain) genotype 1. The emergent 2 strains have become predominant past years that are genetically distant from strain. Here, we aimed to evaluate current infectious status CSF, and for this purpose 24 isolates CSFV were identified different areas during 2016–2018. Phylogenetic analysis NS5B, E2 full genome revealed new...
N(pro) is a multifunctional autoprotease unique to pestiviruses. The interacting partners of the protein classical swine fever virus (CSFV), pestivirus, have been insufficiently defined. Using yeast two-hybrid screen, we identified poly(C)-binding 1 (PCBP1) as novel partner CSFV and confirmed this by coimmunoprecipitation, glutathione S-transferase (GST) pulldown, confocal assays. Knockdown PCBP1 small interfering RNA suppressed growth, while overexpression promoted growth. Furthermore,...
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease associated with progressive joint damage and disability. There lack of effective methods in the treatment RA currently. Many clinical trials have proved that traditional Chinese medicine (TCM) has obvious advantages RA. In this systematic review, we intend to evaluate efficacy safety TCM for active RA.We will search PubMed, Cochrane Library, Embase, Web Science, National Knowledge Infrastructure Database, Wanfang Data,...
This study investigated the fermentation performances and aroma compositions of synthetic grape juice that was fermented by four indigenous non-Saccharomyces yeast isolates were obtained from Shangri-La wine region (China): Meyerozyma guilliermondii (AD-58), Saccharomycopsis vini (BZL-28), Saturnispora diversa (BZL-11), Wickerhamomyces anomalus (DR-110), in comparison to those Saccharomyces cerevisiae (EC1118). The yeasts showed a lower fermentative capacity conversion rate sugar alcohol,...