- Nerve injury and regeneration
- Circular RNAs in diseases
- Sinusitis and nasal conditions
- RNA modifications and cancer
- Laser Applications in Dentistry and Medicine
- Mesenchymal stem cell research
- Bone Metabolism and Diseases
- Dental Radiography and Imaging
- Orthodontics and Dentofacial Orthopedics
- Neuropeptides and Animal Physiology
- Graphene and Nanomaterials Applications
- MicroRNA in disease regulation
- Bone Tissue Engineering Materials
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
Third Affiliated Hospital of Sun Yat-sen University
2018-2021
Sun Yat-sen University
2018-2021
MicroRNAs (miRNAs) have been widely demonstrated to interact with multiple cellular signaling pathways and participate in a wide range of physiological processes. Estradiol-17 β (E2) is the most potent prevalent endogenous estrogen that plays vital role promoting bone formation reducing resorption. Currently, little known about regulation miRNAs E2-induced osteogenic differentiation. In present study, primary marrow mesenchymal stem cells from rats (rBMSCs) were isolated incubated E2,...
Bone regeneration strategies rely on biomaterial constructs with stem cells or growth factors. By comparison, cell homing employ chemokines to recruit the host endogenous progenitor defect site support healing. In present study, we used a novel fluffy hydroxyapatite/polyacrylonitrile (HA/PAN) composite scaffold provide better three-dimensional culture microenvironment. These HA/PAN scaffolds loaded stromal cell-derived factor-1α (SDF-1α) provided diffusion-controlled SDF-1α release profile...