A5057785560- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Autism Spectrum Disorder Research
- Child Abuse and Trauma
- Stress Responses and Cortisol
- Child Nutrition and Feeding Issues
- Child Development and Digital Technology
- Genetics and Neurodevelopmental Disorders
- Eating Disorders and Behaviors
- Suicide and Self-Harm Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Lipid Membrane Structure and Behavior
- Migration, Health and Trauma
- Behavioral and Psychological Studies
- Children's Physical and Motor Development
- Field-Flow Fractionation Techniques
- Substance Abuse Treatment and Outcomes
- Functional Brain Connectivity Studies
- Obsessive-Compulsive Spectrum Disorders
- Posttraumatic Stress Disorder Research
- Schizophrenia research and treatment
- LGBTQ Health, Identity, and Policy
- thermodynamics and calorimetric analyses
- Bipolar Disorder and Treatment
- Personality Disorders and Psychopathology
Uppsala University
2016-2025
Karolinska Institutet
2016-2025
Uppsala University Hospital
2025
Stockholm Health Care Services
2019-2025
UiT The Arctic University of Norway
2022-2023
Centre for Arctic Gas Hydrate, Environment and Climate
2022-2023
University of Gothenburg
2022
Karlstad Central Hospital
2022
National Institute for Environmental Studies
2022
Icahn School of Medicine at Mount Sinai
2022
The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of new treatments, as many may only be effective in particular subgroups. Precision medicine approaches aim overcome this challenge by combining pathophysiologically based treatments stratification biomarkers that predict which treatment most beneficial for individuals. However, so far, we have no single validated biomarker ASD. This due fact...
The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). current paper describes clinical characteristics of LEAP cohort and examines age, sex IQ differences in ASD core symptoms common co-occurring psychiatric symptoms. A companion overall design experimental protocol outlines strategy identify stratification biomarkers. From six research centres four countries, we...
Abstract Only a small number of studies have assessed structural differences between the two hemispheres during childhood and adolescence. However, existing findings lack consistency or are restricted to particular brain region, specific feature, relatively narrow age range. Here, we investigated associations asymmetry as well sex in one largest pediatric samples date ( n = 4265), aged 1–18 years, scanned at 69 sites participating ENIGMA (Enhancing NeuroImaging Genetics through...
Abstract Background In Attention-deficit/hyperactivity disorder (ADHD) the transition from childhood to adolescence encompass changes in symptom manifestation and related challenges. Given potential negative impact of ADHD on adolescents, increased risk for dropping out treatment, there is a need understand more about how adolescents experience their condition. The aim this study was explore adolescents’ perceptions it live with ADHD. Methods Twenty (15–17 years old, 12 girls) diagnosed who...
Alterations in social cognition (SC) are hypothesized to underlie communication and interaction challenges autism spectrum disorder (ASD). The aetiological underpinnings driving this association remain unclear. We examined SC 196 twins with ASD, other neurodevelopmental disorders or typical development using the naturalistic Movie for Assessment of Social Cognition. Autism its severity were assessed Diagnostic Observation Schedule-2, autistic traits Responsiveness Scale-2. Using within...
Atypical sensory processing is prevalent across neurodevelopmental conditions and a key diagnostic criterion of autism spectrum disorder. It may have cascading effects on the development adaptive functions. However, its unique contribution to functioning genetic/environmental influences this link are unclear. In clinically enriched twin sample ( n = 289, 60 diagnosed with disorder), we investigated associations between quadrants Adult/Adolescent Sensory Profile (low registration,...
Eating disorder (ED) symptoms have been associated with different types of traumatic events, such as exposure to sexual and physical violence, emotional abuse. However, the relation between ED community violence (CVE) is underexplored, despite latter's adverse effects on many aspects adolescent functioning. The primary aim this study was evaluate CVE in adolescents, while also investigating potential mediating moderating roles posttraumatic stress (PTS) symptoms, gender, ethnicity. Data were...
Psychotic-like experiences (PLEs), such as delusions and hallucinations, are regarded to occur along a spectrum be present also in non-help-seeking individuals from the general population. However, it remains unclear whether occurrence of PLEs is unique risk factor for future or symptom psychopathology. In this study, we investigated during adolescence predict adulthood. A community-based cohort 1146 young adolescents (mean age, 14.38 years) were assessed then reassessed 6 years later 20.15...
Background Enuresis is a common disorder in the school-age period, and often associated with variety of behavioral, psychological, social problems. While early studies suggested an association between enuresis delinquent behavior, there has been no recent research assessing prevalence its comorbid psychopathology young offenders. The aim this study was to therefore assess psychiatric comorbidity incarcerated Methods past current assessed using semi-structured interview self-reports from 366...
Few studies have addressed gender differences in autism relation to functioning and across cultures. We aimed explore functional from a multidisciplinary, global perspective using the International Classification of Functioning, Disability, Health. Perceptions among professionals high-income countries middle-income were examined based on qualitative survey data N = 225 professionals. Of these, n 131 provided information autism. Thirty-two reported perceiving no differences. Remaining...
Autism spectrum disorder is associated with sensory processing alterations, such as hyper- and hypo-responsiveness. Twin studies are scarce in this field, but they necessary order to disentangle the genetic environmental contributions association. Furthermore, it unclear how different neurodevelopmental/psychiatric conditions contribute altering processing. We investigated association between autistic traits/autism diagnosis alterations twins ( N = 269), using adult/adolescent profile, which...
<h3>Importance</h3> Increasing numbers of transgender and gender diverse children adolescents have been referred to identity clinics in Sweden the past decade, previous studies found an association between media attention referral counts. Whether tone stories is associated with referrals not yet known. <h3>Objective</h3> To investigate whether positive or negative coverage on issues counts child adolescent clinics. <h3>Design, Setting, Participants</h3> In this cross-sectional study, were...
Background and purpose: There is limited data on the real-world management of incidental pulmonary nodules (IPN). In this article, we review current practices adherence to international guidelines in Nordic countries. Materials methods: This non-interventional, observational survey study based an online consisting 13 questions. total, 32 hospitals responded survey, with 11 from Denmark, 10 Sweden, 7 Norway, 4 Finland, resulting overall response rate 86% (32/37). These institutions reported...
Background: Attention-deficit/hyperactivity disorder (ADHD) is linked to high levels of perceived stress in adult populations. Thus, it not surprising that managing techniques are being included treatment protocols for adults with ADHD. There is, however, a paucity studies on adolescents ADHD.Aims: This study aims explore how ADHD perceive and experience (and stressors) using qualitative approach.Methods: Explorative interviews were conducted 20 (Mean age: 16.30) diagnosed conjunction group...
Physical activity (PA) during adolescence is associated with a wide range of health benefits, including lower levels internalizing and externalizing problems. Although the association between PA mental has been established, there are few prospective studies investigating if internalizing/externalizing symptoms remains after adjustment for baseline occurrence such symptoms, those exploring any sex-specific pattern association. Swedish adolescents (N = 1428; mean age 14.38 years) were assessed...
The aim of this study was to examine the validity Gender Dysphoria (GD) diagnoses in Swedish National Patient Register (NPR), discuss different register-based definitions GD and investigate incidence trends. We collected data on all individuals with registered between 2001 2016 as well coverage NPR. regarded gender confirming medical intervention (GCMI) one proxy for a clinically valid diagnosis calculated positive predictive value (PPV) receiving GCMI increasing number diagnoses. assessed...
Background: Many children and adolescents experience violent events which can be associated with negative consequences for their development, mental health, school, social functioning. However, findings between settings on the role of gender have been inconsistent. This study aimed to investigate cross-country differences in relationship community violence exposure (CVE) school functioning a sample youths from three countries. Methods: A self-report survey was conducted among students (12–17...
This study investigated the association between autism and self-reported eating problems influence of gender on association, in a sample adolescent adult twins (N = 192). Autistic traits diagnosis were associated with both total specific problems, including selective sensory sensitivity during mealtimes. Interaction effects indicated stronger autistic females, as well more difficulties social contexts among females. In within-pair analyses, where unmeasured confounders genes shared...
Abstract We examined perceived stress and sleep problems in adolescent ADHD whether this varies as a function of presentation sex. Further, we mapped structural associations between symptoms, comorbid stress, problems. Participants were 306 adolescents aged 13–19 years (66.8% females, 193 had an diagnosis, 113 controls). Parents rated all other constructs self-rated. Adolescents with elevated levels Girls reported the highest stress. Emotional symptoms mediated effect inattention whereas...
Emotion dysregulation (ED) is common in attention-deficit/hyperactivity disorder (ADHD) and often results adverse outcomes. However, ED has been suggested as a transdiagnostic construct, why the specific association between ADHD when adjusting for other mental health conditions needs further investigation. It also important to determine aetiological basis of inform theoretical conceptualization ADHD. This study used co-twin control design, including sample dizygotic (DZ) monozygotic (MZ)...
One strategy to combat antimicrobial resistance is the discovery of new classes antibiotics. Most antibiotics will at some point interact with bacterial membrane either interfere its integrity or cross it. Reliable and efficient tools for determining dissociation constant binding (KD) partitioning coefficient between aqueous- phases (KP) are therefore important discovering optimizing hits. Here we demonstrate that microscale thermophoresis (MST) can be used label-free measurement KD by...