Steven Williams

ORCID: 0000-0003-4299-1941
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About
Contact & Profiles
Research Areas
  • Functional Brain Connectivity Studies
  • Advanced MRI Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Schizophrenia research and treatment
  • Neural and Behavioral Psychology Studies
  • Neuroscience and Neuropharmacology Research
  • Autism Spectrum Disorder Research
  • Prion Diseases and Protein Misfolding
  • EEG and Brain-Computer Interfaces
  • Neural dynamics and brain function
  • Obsessive-Compulsive Spectrum Disorders
  • Alzheimer's disease research and treatments
  • Neurological disorders and treatments
  • Neuroscience and Music Perception
  • Medical Imaging Techniques and Applications
  • Mental Health Research Topics
  • Eating Disorders and Behaviors
  • Pain Management and Placebo Effect
  • Treatment of Major Depression
  • Atomic and Subatomic Physics Research
  • Attention Deficit Hyperactivity Disorder
  • Dementia and Cognitive Impairment Research
  • Psychosomatic Disorders and Their Treatments
  • Diet and metabolism studies
  • Neurobiology of Language and Bilingualism

King's College London
2016-2025

Cornell University
2014-2025

Wellcome Centre for Human Neuroimaging
2015-2025

Weill Cornell Medicine
2022-2025

New York University
2005-2025

University of Edinburgh
2021-2025

DeKalb County Board of Health
2020-2025

Aberystwyth University
2024

Aims Community College
2024

10X Genomics (United States)
2022-2024

Abstract This paper concerns the spatial and intensity transformations that are required to adjust for confounding effects of subject movement during functional MRI (fMRI) activation studies. An approach is presented models, removes, movement‐related artifacts from fMRI time‐series. predicated on observation extant even after perfect realignment. Movement‐related can be divided into those a function position object in frame reference scanner due previous scans. second component depends...

10.1002/mrm.1910350312 article EN Magnetic Resonance in Medicine 1996-03-01

Watching a speaker’s lips during face-to-face conversation (lipreading) markedly improves speech perception, particularly in noisy conditions. With functional magnetic resonance imaging it was found that these linguistic visual cues are sufficient to activate auditory cortex normal hearing individuals the absence of sounds. Two further experiments suggest cortical areas not engaged when an individual is viewing nonlinguistic facial movements but appear be activated by silent meaningless...

10.1126/science.276.5312.593 article EN Science 1997-04-25

OBJECTIVE: Functional magnetic resonance imaging (MRI) was used to investigate the hypothesis that attention deficit hyperactivity disorder (ADHD) is associated with a dysfunction of prefrontal brain regions during motor response inhibition and timing. METHOD: Generic activation seven adolescent boys ADHD compared nine comparison subjects equivalent in sex, age, IQ while they were performing stop task, requiring planned response, timing sensory cue. RESULTS: The hyperactive adolescents...

10.1176/ajp.156.6.891 article EN American Journal of Psychiatry 1999-06-01

Neuropsychological studies report more impaired responses to facial expressions of fear than disgust in people with amygdala lesions, and vice versa Huntington's disease. Experiments using functional magnetic resonance imaging (fMRI) have confirmed the role response fearful faces implicated anterior insula disgust. We used fMRI extend these perception from both vocal expressions. Consistent neuropsychological findings, types stimuli activated amygdala. Facial caudate-putamen; did not...

10.1098/rspb.1998.0506 article EN Proceedings of the Royal Society B Biological Sciences 1998-10-07

Although high-functioning individuals with autistic disorder (i.e. autism and Asperger syndrome) are of normal intelligence, they have life-long abnormalities in social communication emotional behaviour. However, the biological basis difficulties is poorly understood. Facial expressions help shape behaviour, we investigated if people show neurobiological differences from controls when processing facial expressions. We used functional MRI to investigate brain activity nine adults (mean age ±...

10.1093/brain/123.11.2203 article EN Brain 2000-11-01

<h3>Aim</h3> To evaluate the association between serum levels of complement component (C) 3, C4 and C1q visual field (VF) loss in patients with primary angle closure glaucoma (PACG). <h3>Methods</h3> In this prospective cohort study, a total 308 PACG were included. The followed up every 6 months (at least 2 years), clinical examination VF testing. Based on their sex age, subjects stratified into male female subgroups, by age at &lt;60 ≥60 years per subgroup. <h3>Results</h3> One hundred...

10.1212/wnl.57.4.632 article EN Neurology 2001-08-28

<h3>Background</h3> Depression is associated with interpersonal difficulties related to abnormalities in affective facial processing. <h3>Objectives</h3> To map brain systems activated by sad affect processing patients depression and identify functional correlates of antidepressant treatment symptomatic response. <h3>Design</h3> Two groups underwent scanning twice using magnetic resonance imaging (fMRI) during an 8-week period. The event-related fMRI paradigm entailed incidental recognition...

10.1001/archpsyc.61.9.877 article EN Archives of General Psychiatry 2004-09-01

Abstract Two questions arising In the analysis of functional magnetic resonance imaging (fMRI) data acquired during periodic sensory stimulation are: i) how to measure experimentally determined effect in fMRI time series; and ii) decide whether an apparent is significant Our approach first fit a series regression model, including sine cosine terms at (fundamental) frequency experimental stimulation, by pseudogeneralized least squares (PGLS) each pixel image. Sinusoidal modeling takes account...

10.1002/mrm.1910350219 article EN Magnetic Resonance in Medicine 1996-02-01

Perceptions of speech in the absence an auditory stimulus (auditory verbal hallucinations) are a cardinal feature schizophrenia. Functional neuroimaging provides powerful means measuring neural activity during hallucinations, but results from previous studies have been inconsistent. This may reflect acquisition small numbers images each subject and confounding effects patients actively signaling when hallucinations occur.We examined 6 with schizophrenia who were experiencing frequent using...

10.1001/archpsyc.57.11.1033 article EN Archives of General Psychiatry 2000-11-01

Abstract Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and heterogeneous with multiple contributors to its pathophysiology, including vascular dysfunction. The recently updated AD Research Framework put forth by the National Institute on Aging–Alzheimer's Association describes biomarker‐based pathologic definition of focused amyloid, tau, neuronal injury. In response this article, here we first discussed that dysfunction is an important early event in...

10.1016/j.jalz.2018.07.222 article EN Alzheimer s & Dementia 2019-01-01
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