A5070893028- Sepsis Diagnosis and Treatment
- Immune Response and Inflammation
- MicroRNA in disease regulation
- Advanced Battery Materials and Technologies
- T-cell and B-cell Immunology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Colorectal Cancer Screening and Detection
- Alzheimer's disease research and treatments
- Cancer-related molecular mechanisms research
- Heart Rate Variability and Autonomic Control
- Circular RNAs in diseases
- RNA Research and Splicing
- Hematological disorders and diagnostics
- Supercapacitor Materials and Fabrication
- Intensive Care Unit Cognitive Disorders
- Parathyroid Disorders and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Advancements in Battery Materials
- Cardiovascular and exercise physiology
- Renal function and acid-base balance
Sun Yat-sen Memorial Hospital
2017-2023
Sun Yat-sen University
2017-2023
Fujian Normal University
2022
Chinese Academy of Sciences
2022
Fujian Institute of Research on the Structure of Matter
2022
Abstract Natural pathogens, such as viruses, often induce T-dependent and T-independent Ab responses. However, the activation differentiation of Ag-specific B cells under these conditions had not been examined in detail. In this study, we used bacterial phage Qβ-derived virus-like particles (Qβ-VLPs) an immunogen to examine phases response mice. Using Qβ-specific cell labeling enrichment methods developed were able characterize rare Surprisingly, found that Qβ-VLPs could Bcl-6 expression...
MicroRNAs have become pivotal modulators in the pathogenesis of Alzheimer's disease. MiR-338-5p is associated with neuronal differentiation and neurogenesis, expressed aberrantly patients cognitive dysfunction. However, its role potential mechanism involved disease remain to be elucidated. Herein, we showed that expression miR-338-5p decreased APP/PS1 mice, accompanied by elevation level amyloid β, which indicated a reverse relationship between progression miR-338-5p. In addition, lentiviral...
Objective. The prognostic value of the red cell distribution width (RDW) in patients with sepsis-induced acute respiratory distress syndrome (ARDS) is still elusive. This study aimed at determining whether RDW a indicator ARDS. Methods. retrospective cohort included 1161 datasets were acquired from Medical Information Mart for Intensive Care III database. locally weighted scatter-plot smoothing technique, Cox regression, Kaplan-Meier estimator, and subgroup analysis carried out to evaluate...
Sepsis is common in intensive care units and has a high mortality rate; yet, its pathogenesis treatment remain unclear. Recent studies have shown that long non-coding RNA plasmacytoma variant translocation 1 (lncRNA-PVT1) plays pro-inflammatory role immune-related inflammatory diseases. Therefore, we investigated whether lncRNA-PVT1 an important effect the response of sepsis.Quantitative real-time PCR (RT-qPCR) was employed for detection lncRNA-PVT1, interleukin 1β (IL-1β), tumor necrosis...
Introduction Sepsis is a life-threatening complication resulting from dysregulated host response to serious infection, of which bacteria are the most common cause. A rapid differentiation gram negative (G - )/gram positive + ) pathogens facilitates antibiotic treatment, in turn improves patients’ survival. Methods We performed prospective, observational study adult patients intensive care unit (ICU) and underwent analysis peripheral blood lymphocyte subsets, cytokines other clinical indexes....